Tyrosine decaging leads to substantial membrane trafficking during modulation of an inward rectifier potassium channel

Journal of General Physiology

Volumn 117, Issue 2, 2001, Pages 103-118

  Tong, Yanhe ^a   Brandt, Gabriel S ^b   Li, Ming ^a   Shapovalov, George ^a   Slimko, Eric ^a   Karschin, Andreas ^c   Dougherty, Dennis A ^b   Lester, Henry A ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b California Institute of Technology   (United States)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Clathrin; Endocytosis; Ion channel; Kir2.1; Unnatural amino acids

Indexed keywords

ADAPTOR PROTEIN; CLATHRIN; DYNAMIN; MALEIMIDE DERIVATIVE; MEMBRANE PROTEIN; POTASSIUM CHANNEL; THIOL; TYROSINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME ACTIVATION; MEMBRANE TRANSPORT; NONHUMAN; OOCYTE; POTASSIUM CURRENT; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; XENOPUS;

EID: 0035003359     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.117.2.103     Document Type: Article

References (62)

1. Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes
2. Protein kinase C regulation of cardiac calcium channels expressed in Xenopus oocytes
3. Neurotrophin receptors: A window into neuronal differentiation
4. Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts
5. Caged regulators of signaling pathways
6. Light-activated proteins
7. Induction of mutant dynamin specifically blocks endocytic-coated vesicle formation
8. A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
9. Site-specific, photochemical proteolysis applied to ion channels in vivo
10. Number of subunits comprising the epithelial sodium channel
11. Activation of protein tyrosine kinase PYK2 by the mI muscarinic acetylcholine receptor
12. Ligand-induced endocytosis of the EGF receptor is blocked by mutational inactivation and by microinjection of anti-phosphotyrosine antibodies
13. AP-2 recruitment to synaptotagmin stimulated by tyrosine-based endocytic motifs
14. +/glucose cotransporter expression by protein kinases in Xenopus laevis oocytes
15. Tyrosine phosphorylation of the Kv1.3 potassium channel
16. Association of Src tyrosine kinase with a human potassium channel mediated by SH3 domain
17. 2 and its stabilization by Gβγ
18. Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadate
19. 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif
20. + channels expressed in Xenopus oocytes
21. Regulation of potassium channels by protein kinases
22. Linking cargo to vesicle formation: Receptor tail interactions with coat proteins
23. Primary structure and functional expression of a mouse inward rectifier potassium channel
24. Modulation of ion channels by protein phosphorylation. How the brain works
25. An intermediate state of the GABA transporter GAT1 revealed by simultaneous voltage clamp and fluorescence
26. + channel in the presence of Src tyrosine kinase
27. Caged peptides and proteins: New probes to study polypeptide function in complex biological systems
28. Flash decaging of tyrosine sidechains in an ion channel
29. + channels by β-adrenergic stimulation via cAMP-dependent protein kinase
30. Effects of PS1 deficiency on membrane protein trafficking in neurons
31. Neuronal Kit channels differentially couple to PDZ proteins of the PSD-95/SAP90 family
32. A general-method for site-specific incorporation of unnatural amino-acids into proteins
33. Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells
34. In vivo incorporation of unnatural amino acids into ion channels in a Xenopus oocyte expression system
35. The medium subunits of adaptor complexes recognize distinct but overlapping sets of tyrosine-based sorting signals
36. A structural explanation for the recognition of tyrosine-based endocytotic signals
37. Effects of the protein tyrosine phosphatase inhibitor phenylarsine oxide on excision-activated calcium channels in Lymnaea neurons
38. Caged cysteine and thiophosphoryl peptides
39. Syntaxin IA inhibits regulated CFTR trafficking in Xenopus oocytes
40. Second messengers, trafficking-related proteins, and amino acid residues that contribute to the functional regulation of the rat brain GABA transporter GAT1
41. Novel method for evaluation of the oligomeric structure of membrane proteins
42. Apoptosis but not other activation events is inhibited by a mutation in the transmembrane domain of T cell receptor β that impairs CD3ζ association
43. TrkB activation by BDNF inhibits the G protein gated inward rectifier Kir3 by tyrosine phosphorylation of the channel
44. + channels
45. An engineered Tetrahymena tRNAGIn for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression
46. A putative vacuolar cargo receptor partially colocalizes with AtPEP12p on a prevacuolar compartment in Arabidopsis roots
47. Growth factor signaling by receptor tyrosine kinases
48. The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis
49. Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2
50. Functional analysis of immunoreceptor tyrosine-based activation motif (ITAM)-mediated signal transduction: The two YxxL segments within a single CD3ζ-ITAM are functionally distinct
51. Insulin-like growth factor 1 receptor-mediated endocytosis in Xenopus laevis oocytes. A role for receptor tyrosine kinase activity
52. CFTR-dependent membrane insertion is linked to stimulation of the CFTR chloride conductance
53. Identification and characterisation of Xenopus moesin, a Src substrate in Xenopus laevis oocytes
54. Modulation of a voltage-activated potassium channel by peptide growth factor receptors
55. Mutations in human dynamin block an intermediate stage in coated vesicle formation
56. Receptor protein-tyrosine kinases and their signal transduction pathways
57. +-ATPase in oocytes of Xenopus laevis
58. Analysis of immunoreceptor tyrosinobased activation motif (ITAM) binding to ZAP-70 by surface plasmon resonance
59. Acute suppression of inwardly rectifying Kir2.1 channels by direct tyrosine kinase phosphorylation
60. NMDA channel regulation by channel-associated protein tyrosine kinase Src
61. A method for determining the unitary functional capacity of cloned channels and transporters expressed in Xenopus laevis oocytes