AP-2 recruitment to synaptotagmin stimulated by tyrosine-based endocytic motifs

Science

Volumn 285, Issue 5431, 1999, Pages 1268-1271

  Haucke, Volker ^a   De Camilli, Pietro ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; MEMBRANE PROTEIN; PROTEIN SUBUNIT; SYNAPTOTAGMIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENDOCYTOSIS; GOLGI COMPLEX; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; RAT;

ADAPTOR PROTEIN COMPLEX ALPHA SUBUNITS; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; BINDING SITES; CALCIUM-BINDING PROTEINS; CATTLE; CELL MEMBRANE; CHO CELLS; CLATHRIN; COATED PITS, CELL-MEMBRANE; CRICETINAE; ENDOCYTOSIS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; NERVE TISSUE PROTEINS; NEURONS; OLIGOPEPTIDES; PHOSPHOLIPASE D; PROTEIN BINDING; RATS; RECOMBINANT FUSION PROTEINS; SYNAPTIC MEMBRANES; SYNAPTOTAGMINS; TYROSINE;

EID: 0033588035     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.285.5431.1268     Document Type: Article

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36. We thank T. F. Martin (University of Wisconsin) for the antiserum to the C2B domain of synaptotagmin, R. Jahn (Max-Planck Institute, Goettingen) for monoclonal antibodies to synaptotagmin I, and members of the De Camilli lab for discussions. Supported by grants from the NIH (NS36252 and CA46128) to P.D.C. and a fellowship from the Human Frontier Science Program to V.H.