Heterologous facilitation of G protein-activated K+ channels by β- adrenergic stimulation via cAMP-dependent protein kinase

Journal of General Physiology

Volumn 115, Issue 5, 2000, Pages 547-557

  Müllner, Carmen ^a   Vorobiov, Dimitry ^b   Bera, Amal Kanti ^b   Uezono, Yasuhito ^b,c   Yakubovich, Daniel ^b   Frohnwieser Steinecker, Bibiane ^a   Dascal, Nathan ^b   Schreibmayer, Wolfgang ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b TEL AVIV UNIVERSITY   (Israel)

^c UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Cardiomyocytes; G protein activated inwardly rectifying K+ channels; Heterologous facilitation; Protein kinase A; Xenopus

Indexed keywords

ACETYLCHOLINE; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NYSTATIN; POTASSIUM CHANNEL;

ADRENERGIC SYSTEM; ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HEART ATRIUM; HEART MUSCLE CELL; NONHUMAN; OOCYTE; PATCH CLAMP; RAT; XENOPUS;

ACETYLCHOLINE; ADRENERGIC BETA-AGONISTS; ANIMALS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GENE EXPRESSION; HEART ATRIA; ION CHANNEL GATING; ISOPROTERENOL; ISOQUINOLINES; MEMBRANE POTENTIALS; MUSCLE FIBERS; MYOCARDIUM; OOCYTES; PHOSPHORYLATION; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, BETA; SULFONAMIDES; THIONUCLEOTIDES; VASODILATOR AGENTS; XENOPUS LAEVIS;

EID: 0342858980     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.115.5.547     Document Type: Article

References (34)

1. Anderson, M.P., H.A. Berger, D.P Rich, R.J. Gregory, A.E. Smith, and M.J. Welsh. 1991. Nucleoside triphosphates are required to open the CFTR chloride channel. Cell. 67:775-784.
2. 1 subunit of heterotrimeric G proteins. FEBS Lett. 439:115-120.
3. αs in Xenopus oocytes. FEBS Lett. 444:78-84.
4. 2+ channel modulation by 8-bromocyclic AMP in cultured heart cells. Nature. 304:462-464.
5. + currents in rat serotonergic neurones. J. Physiol. 496:129-137.
6. Cheng, S.H., D.P. Rich, J. Marshall, R.J. Gregory, M.W. Welsh, and A.E. Smith. 1991. Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel. Cell. 66:1027-1036.
7. KACh. J. Biol. Chem. 273:5271-5278.
8. Daaka, Y., L.M. Luttrell, and R.J. Lefkowitz. 1997. Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A. Nature. 390:88-91.
9. + channels. Cell. Signal. 9:551-573.
10. + channel: expression cloning and molecular properties. Proc. Natl. Acad. Sci. USA.90:10235-10239.
11. Dascal, N., and I. Lotan. 1992. Expression of exogenous ion channels and neurotransmitter receptors in RNA-injected Xenopus oocytes. In Methods in Molecular Neurobiology. Vol. 13. A. Longstaff and P. Revest, editors. Humana Press, Totowa, NJ. 205-225.
12. βγ subunits in Xenopus oocytes. J. Gen. Physiol. 105: 421-439.
13. Frohnwieser, B., L.-Q. Chen, W. Schreibmayer, and R.G. Kallen. 1997. Modulation of the human cardiac sodium channel α-subunit by cAMP and the responsible sequence domain. J. Physiol. 498:309-318.
14. + channel subunit that permits GIRK1 expression of IKACh currents in oocytes. Neuron. 16:423-429.
15. + channels. FEBS Lett. 405:291-298.
16. + channel composed of Kv1.1 and Kvβ1.1 subunits modulated by G protein βγ subunits. EMBO (Eur. Mol. Biol. Organ.) J. 18:1245-1256.
17. + channel via cyclic AMP-dependent protein kinase in atrial cells. Circ. Res. 67:1292-1298.
18. + channel determined by construction of multimeric cDNAs. Neuron. 9:861-871.
19. + channel (GIRK) expressed in Xenopus oocytes. J. Physiol. 505:13-22.
20. Murray, R., and E. Spiegel. 1961. Theory and Problems of Statistics. McGraw-Hill Book Co., New York, NY. 167-184.
21. Nargeot, J., J.M. Nerbonne, J. Engels, and H.A. Lester. 1983. Time course of the increase in myocardial slow inward current after photochemically generated concentration jump of intracellular cyclic AMP. Proc. Natl. Acad. Sci. USA. 80:2395-2399.
22. Pitcher, J.A., N.J. Freedman, and R.J. Lefkowitz. 1998. G protein-coupled receptor kinases. Annu. Rev. Biochem. 67:653-692.
23. 2+ current. Nature. 298:576-578.
24. IC subunit. FEBS Lett. 384:189-192.
25. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. 2nd ed. CSH Press, New York, NY.
26. + channel by G-protein alpha-subunits. Nature. 380:624-627.
27. Schreibmayer, W., H.A. Lester, and N. Dascal. 1994. Voltage clamp of Xenopus laevis oocytes utilizing agarose-cushion electrodes. Pflügers Arch. 426:453-458.
28. + channel, GIRK, in Xenopus oocytes. J. Gen. Physiol. 109:477-490
29. + channel. J. Biol. Chem. 271:30524-30528.
30. s-derived bg subunits. J. Physiol. 514:413-423.
31. Trautwein, W., J. Taniguchi, and A. Noma. 1982. The effect of intracellular cyclic nucleotides and calcium on the action potential and acetylcholine response of isolated cardiac cells. Pflügers Arch. 392:307-314.
32. Uezono, Y., J. Bradley, C. Min, N.A. McCarty, M. Quick, J.R. Riordan, C. Chavkin, K. Zinn, H.A. Lester, and N. Davidson. 1993. Receptors that couple to 2 classes of G proteins increase cAMP and activate CFTR expressed in Xenopus oocytes. Receptors Channels, 1:233-241.
33. + current in cat atrial myocytes. Circ. Res. 77:565-574.
34. Wellner-Kienitz, M.C., K. Bender, B. Brandts, T. Meyer, and L. Pott. 1999. Antisense oligonucleotides against receptor kinase GRK2 disrupt target selectivity of β-adrenergic receptors in atrial myocytes. FEBS Lett. 451:279-283.