Functional analysis of immunoreceptor tyrosine-based activation motif (ITAM)-mediated signal transduction: The two YxxL segments within a single CD3ζ-ITAM are functionally distinct

European Journal of Immunology

Volumn 27, Issue 8, 1997, Pages 2001-2009

  Sunder Plassmann, Raute ^a,b   Lialios, Paye ^b   Madsen, Mari ^b   Koyasu, Shigeo ^a,b,c   Reinherz, Ellis L ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c KEIO UNIVERSITY   (Japan)

Author keywords

Ca2+; CD3s immunoreceptor tyrosine based activation motif; Interleukin 2; JCaM1.6; p56(lck); ZAP70

Indexed keywords

ALANINE; CALCIUM ION; CD3 ANTIGEN; INTERLEUKIN 2; LEUCINE; LYMPHOCYTE RECEPTOR; PHOSPHOLIPASE C; TYROSINE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CALCIUM MOBILIZATION; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD3; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-2; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MICE; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PHOSPHOPEPTIDES; PHOSPHORYLATION; POINT MUTATION; PROTEIN-TYROSINE KINASES; RECEPTORS, IMMUNOLOGIC; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TYROSINE; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 0030739987     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.1830270826     Document Type: Article

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