An updated topographical model for phosphodiesterase 4 (PDE4) catalytic site

Quantitative Structure-Activity Relationships

Volumn 20, Issue 1, 2001, Pages 17-22

  Fossa, Paola ^a   Menozzi, Giulia ^a   Mosti, Luisa ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

DISCO; HINT; PDE4 selective inhibitors; Pharmacophoric model

Indexed keywords

BINDING ENERGY; DISEASES; ESTERS; NUCLEOTIDES;

CATALYTIC SITES; CLINICAL STUDY; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES; DISCO; HINT; PHARMACOPHORIC MODEL; PHOSPHODIESTERASE 4-SELECTIVE INHIBITOR; PHOSPHODIESTERASE-4; PRECLINICAL STUDIES; SELECTIVE INHIBITORS;

ENZYMES;

PHOSPHODIESTERASE IV; ROLIPRAM;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; MOLECULAR MODEL; PRIORITY JOURNAL; RECEPTOR AFFINITY;

EID: 0034993413     PISSN: 09318771     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3838(200105)20:1<17::AID-QSAR17>3.0.CO;2-X     Document Type: Article

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