Salmonella pathogenicity islands encoding type III secretion systems

Microbes and Infection

Volumn 3, Issue 7, 2001, Pages 549-559

  Hansen Wester, Imke ^a   Hensel, Michael ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Intracellular pathogenesis; Invasion; Salmonella pathogenicity islands; Type III secretion systems

Indexed keywords

BACTERIAL PROTEIN;

BACTERIAL VIRULENCE; CELL DIVISION; CELL INTERACTION; EVOLUTION; GENE EXPRESSION REGULATION; GENETIC CODE; GENETIC ORGANIZATION; INTESTINE EPITHELIUM CELL; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SECRETION; PROTEIN STRUCTURE; REVIEW; SALMONELLA ENTERICA; SURVIVAL;

SALMONELLA; SALMONELLA ENTERICA;

EID: 0034971522     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(01)01411-3     Document Type: Review

References (66)

1. Typhoid fever and other salmonellosis: A continuing challenge
2. How Salmonella became a pathogen
3. Salmonella pathogenicity islands: Big virulence in small packages
4. Molecular genetic bases of Salmonella entry into host cells
5. Salmonella pathogenicity island 2
6. Molecular basis of Salmonella-induced enteritidis
7. Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches
8. Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes
9. The varied lifestyles of intracellular pathogens within eukaryotic vacuolar compartments
10. Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent
11. Inhibition of macrophage phagosome-lysosome fusion by Salmonella typhimurium
12. Salmonella typhimurium activates virulence gene transcription within acidified macrophage phagosomes
13. The unique trafficking pattern of Salmonella typhimurium-containing phagosomes in murine macrophages is independent of the mechanism of bacterial entry
14. Cloning and molecular characterization of genes whose products allow Salmonella typhimurium to penetrate tissue culture cells
15. Simultaneous identification of bacterial virulence genes by negative selection
16. The Salmonella typhimurium invasion genes invF and invG encode homologues of the AraC and PulD family of proteins
17. Cognate gene clusters govern invasion of host epithelial cells by Salmonella typhimurium and Shigella flexneri
18. Salmonella typhimurium secreted invasion determinants are homologous to Shigella Ipa proteins
19. PhoP/PhoQ transcriptional repression of Salmonella typhimurium invasion genes: Evidence for a role in protein secretion
20. A 40 kb chromosomal fragment encoding Salmonella typhimurium invasion genes is absent from the corresponding region of the Escherichia coli K-12 chromosome
21. Identification of a virulence locus encoding a second type III secretion system in Salmonella typhimurium
22. Type III protein secretion systems in bacterial pathogens of animals and plants
23. Supramolecular structure of the Salmonella typhimurium type III protein secretion system
24. Salmonella typhimurium encodes a putative iron transport system within the centisome 63 pathogenicity island
25. The genetic basis of tetrathionate respiration in Salmonella typhimurium
26. The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
27. Direct nucleation and bundling of actin by the SipC protein of invasive Salmonella
28. Role of the S. typhimurium actin-binding protein SipA in bacterial internalization
29. A secreted protein tyrosine phosphatase with modular effector domains in the bacterial pathogen Salmonella typhimurium
30. A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion
31. SopE, a secreted protein of Salmonella dublin, is translocated into the target eukaryotic cell via a sip-dependent mechanism and promotes bacterial entry
32. A substrate of the centisome 63 type III protein secretion system of Salmonella typhimurium is encoded by a cryptic bacteriophage
33. Identification of a pathogenicity island required for Salmonella enteropathogenicity
34. A secreted effector protein of Salmonella dublin is translocated into eukaryotic cells and mediates inflammation and fluid secretion in infected ileal mucosa
35. SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase
36. S. typhimurium encodes an activator of Rho GTPases that induces membrane ruffling and nuclear responses in host cells
37. Identification of SopE2, a Salmonella secreted protein which is highly homologous to SopE and involved in bacterial invasion of epithelial cells
38. Identification of SopE2 from Salmonella typhimurium, a conserved guanine nucleotide exchange factor for Cdc42 of the host cell
39. Influence of the Salmonella typhimurium pathogenicity island 2 type III secretion system on bacterial growth in the mouse
40. Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival
41. Genes encoding putative effector proteins of the type III secretion system of Salmonella pathogenicity island 2 are required for bacterial virulence and proliferation in macrophages
42. Identification of a pathogenicity island required for Salmonella survival in host cells
43. Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase
44. pH-dependent secretion of SseB, a product of the SPI-2 type III secretion system of Salmonella typhimurium
45. A Salmonella virulence protein that inhibits cellular trafficking
46. Salmonella typhimurium leucine-rich repeat proteins are targeted to the SPI1 and SPI2 type III secretion systems
47. The ability of Salmonella to enter mammalian cells is affected by bacterial growth state
48. Identification and characterization of a Salmonella typhimurium oxygen-regulated gene required for bacterial internalization
49. Expression of Salmonella typhimurium genes required for invasion is regulated by changes in DNA supercoiling
50. Co-ordinate regulation of Salmonella typhimurium invasion genes by environmental and regulatory factors is mediated by control of hilA expression
51. Fluorescence-based isolation of bacterial genes expressed within host cells
52. Environmental regulation of Salmonella pathogenicity island 2 gene expression
53. Unravelling the mysteries of virulence gene regulation in Salmonella typhimurium
54. hilA is a novel ompR/toxR family member that activates the expression of Salmonella typhimurium invasion genes
55. 2+ as an extracellular signal: Environmental regulation of Salmonella virulence
56. PhoP/PhoQ: Macrophage-specific modulators of Salmonella virulence?
57. Transcriptional activation of Salmonella typhimurium invasion genes by a member of the phosphorylated response-regulator superfamily
58. Salmonella SirA is a global regulator of genes mediating enteropathogenesis
59. OmpR regulates the two-component system SsrA-SsrB in Salmonella pathogenicity island 2
60. Mutations in Salmonella pathogenicity island 2 (SPI2) genes affecting transcription of SPI1 genes and resistance to antimicrobial agents
61. Analysis of the boundaries of Salmonella pathogenicity island 2 and the corresponding chromosomal region of Escherichia coli K-12
62. Naturally occurring deletions in the centisome 63 pathogenicity island of environmental isolates of Salmonella spp
63. Distribution of pathogenicity islands in Salmonella spp
64. Functional analysis of ssaJ and the ssaK/U operon, 13 genes encoding components of the type III secretion apparatus of Salmonella pathogenicity island 2
65. Molecular and functional analysis indicates a mosaic structure of Salmonella pathogenicity island 2
66. Isolation of a temperate bacteriophage encoding the type III effector protein SopE from an epidemic Salmonella typhimurium strain