Molecular genetic bases of Salmonella entry into host cells

Molecular Microbiology

Volumn 20, Issue 2, 1996, Pages 263-271

  Galán, Jorge E ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN;

CELL ADHESION; CELL INVASION; EPITHELIUM CELL; MOLECULAR GENETICS; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN SECRETION; REVIEW; SALMONELLA; SHIGELLA;

ANIMALS; CHROMOSOMES, BACTERIAL; HUMANS; SALMONELLA;

EID: 0029879556     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2958.1996.tb02615.x     Document Type: Review

References (43)

1. Altmeyer, R.M., McNern, J.K., Bossio, J.C., Rosenshine, I., Finlay, B.B., and Galán, J.E. (1993) Cloning and molecular characterization of a gene involved in Salmonella adherence and invasion of cultured epithelial cells. Mol. Microbiol 7: 89-98.
2. Behlau, I., and Miller, S.J. (1993) A Pho-P-repressed gene promotes Salmonella typhimurium invasion of epithelial cells. J Bacteriol 175: 4475-4484.
3. Collazo, C., and Galán, J.E. (1996) Requirement of exported proteins for secretion through the invasion-associated Type III system in Salmonella typhimurium. Infect Immun, in press.
4. Collazo, C.M., Zierler, M.K., and Galán, J.E. (1995) Functional analysis of the Salmonella typhimurium invasion genes invI and invJ and identification of a target of the protein secretion apparatus encoded in the inv locus. Mol Microbiol 15: 25-38.
5. 1 ATPase family of proteins. J Bacteriol 176: 4501-4510.
6. Elsinghorst, E.A., Baron, L.S., and Kopecko, D.J. (1989) Penetration of human intestinal epithelial cells by Salmonella: molecular cloning and expression of Salmonella typhi invasion determinants in Escherichia coli. Proc Natl Acad Sci USA 86: 5173-5177.
7. Ernst, R.K., Domboski, D.M., and Merrick, J.M. (1990) Anaerobiosis, Type 1 fimbriae, and growth phase are factors that affect invasion of Hep-2 cells by Salmonella typhimurium. Infect Immun 58: 2014-2016.
8. Finlay, B.B. (1994) Molecular and cellular mechanisms of Salmonella pathogenesis. Curr Top Microbiol 192: 163-185.
9. Galán, J.E. (1994) Salmonella entry into mammalian cells: different yet converging signal transduction pathways? Trends Cell Biol 4: 196-199.
10. Galán, J.E. (1995) Molecular and cellular bases of Salmonella entry into non-phagocytic cells. Curr Top Microbiol Immunol 209: 43-60.
11. Galán, J.E., and Curtiss, III, R. (1989) Cloning and molecular characterization of genes whose products allow Salmonella typhimurium to penetrate tissue culture cells. Proc Natl Acad Sci USA 86: 6383-6387.
12. Galán, J.E., and Curtiss, III, R. (1990) Expression of Salmonella typhimurium genes required for invasion is regulated by changes in DNA supercoiling. Infect Immun 58: 1879-1885.
13. Galán, J.E., Ginocchio, C., and Costeas, P. (1992) Molecular and functional characterization of the Salmonella typhimurium invasion gene invA: homology of InvA to members of a new protein family. J Bacteriol 17: 4338-4349.
14. Ginocchio, C. (1994) Characterization of the Salmonella typhimurium invasion genes invA and invE. Thesis, State University of New York at Stony Brook, USA.
15. Ginocchio, C., and Galán, J.E. (1995) Functional conservation among members of the Salmonella typhimurium InvA family of proteins. Infect Immun 63: 729-732.
16. Ginocchio, C., Pace, J., and Galán, J.E. (1992) Identification and molecular characterization of a Salmonella typhimurium gene involved in triggering the internalization of salmonellae into cultured epithelial cells. Proc Natl Acad Sci USA 89: 5976-5980.
17. Ginocchio, C., Olmsted, S.B., Wells, C.L., and Galán, J.E. (1994) Contact with epithelial cells induces the formation of surface appendages on Salmonella typhimurium. Cell 76: 717-724.
18. Groisman, E.A., and Ochman, H. (1993) Cognate gene clusters govern invasion of host epithelial cells by Salmonella typhimurium and Shigella flexneri. EMBO J 12: 3779-3787.
19. Hensel, M., Shea, J.E., Gleeson, C., Jones, M.D., Dalton, E., and Holden, D.W. (1995) Simultaneous identification of bacterial virulence genes by negative selection. Science 269: 400-403.
20. Hermant, D., Ménard, R., Arricau, N., Parsot, C., and Popoff, M.Y. (1995) Functional conservation of the Salmonella and Shigella effectors of entry into epithelial cells. Mol Microbiol 17: 781-789.
21. Jones, B.D., and Falkow, S. (1994) Identification and characterization of a Salmonella typhimurium oxygen-regulated gene required for bacterial internalization. Infect Immun 62: 3745-3752.
22. Kaniga, K., Bossio, J.C., and Galán, J.E. (1994) The Salmonella typhimurium invasion genes invF and invG encode homologues to the PulD and AraC family of proteins. Mol Microbiol 13: 555-568.
23. Kaniga, K., Tucker, S.C., Trollinger, D., and Galán, J.E. (1995a) Homologues of the Shigella invasins IpaB and IpaC are required for Salmonella typhimurium entry into cultured cells. J Bacteriol 177: 3965-3971.
24. Kaniga, K., Trollinger, D., and Galán, J.E. (1995b) Identification of two targets of the type III secretion system encoded in the inv and spa loci of Salmonella typhimurium that share homology to IpaD and IpaA proteins. J Bacteriol 177: 7078-7085.
25. Lee, C.A., and Falkow, S. (1990) The ability of Salmonella to enter mammalian cells is affected by bacterial growth state. Proc Natl Acad Sci USA 87: 4304-4308.
26. Lee, C.A., Jones, B.D., and Falkow, S. (1992) Identification of a Salmonella typhimurium invasion locus by selection of hyperinvasive mutants. Proc Natl Acad Sci USA 89:1847-1851.
27. Li, J., Ochman, H., Groisman, E.A., Boyd, E.F., Salomon, F., Nelson, K., and Selander, R.K. (1995) Relationship between evolutionary rate and cellular location among the Inv/Spa invasion proteins of Salmonella enterica. Proc Natl Acad Sci USA 92: 7252-7256.
28. Ménard, R., Sansonetti, P.J., and Parsot, C. (1994a) The secretion of the Shigella flexneri Ipa invasins is induced by the epithelial cell and controlled by IpaB and IpaD. EMBO J 13: 5293-5302.
29. Ménard, R., Sansonetti, P.J., Parsot, C., and Vasselon, T. (1994b) The IpaB and IpaC invasins of Shigella flexneri associate in the extracellular medium and are partitioned in the cyoplasm by a specific chaperone. Cell 79: 515-529.
30. Mills, D.B., Bajaj, V., and Lee, C.A. (1995) A 40 kilobase chromosomal fragment encoding Salmonella typhimurium invasion genes is absent from the corresponding region of the Escherichia coli K-12 chromsome. Mol Microbiol 15: 749-759.
31. Miras, I., Hermant, D., Arricau, N., and Popoff, M.Y. (1995) Nucleotide sequence of iagA and iagB genes involved in invasion of HeLa cells by Salmonella enterica subsp. enterica ser. Typhi. Res Microbiol 146: 17-20.
32. Parsot, C., Ménard, R., Gounon, P., and Sansonetti, P.J. (1995) Enhanced secretion through the Shigella flexneri Mxi-Spa translocon leads to assembly of extracellular proteins into macromolecular structures. Mol Microbiol 16: 291-300.
33. Pegues, D.A., Hantman, M.J., Behlau, I., and Miller, S.I. (1995) PhoP/PhoQ transcriptional repression of Salmonella typhimurium invasion genes: evidence for a role in protein secretion. Mol Microbiol 17: 169-181.
34. Rosqvist, R., Magnusson, K.E., and Wolf-Watz, H. (1994) Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells. EMBO J 13: 964-972.
35. Rosqvist, R., Hakansson, S., Forsberg, Å., and Wolf-Watz, H. (1995) Functional conservation of the secretion and translocation machinery for virulence proteins of yersiniae, salmonellae and shegellae. EMBO J 14: 4187-4195.
36. Salmond, G.P.C., and Reeves, P.J. (1993) Membrane traffic wardens and protein secretion in Gram-negative bacteria. Trends Biochem Sci 18: 7-12.
37. Stone, B.J., Garcia, C.M., Badger, J.L., Hassett, T., Smith, R.I.F., and Miller, V. (1992) Identification of novel loci affecting entry of Salmonella enteritidis into eukaryotic cells. J Bacteriol 174: 3945-3952.
38. Straley, S.C., Skrzypek, E., Plano, G.V., and Bliska, J.B. (1993) Yops of Yersinia spp. pathogenic for humans. Infect Immun 61: 3105-3110.
39. Watarai, M., Tobe, T., Yoshikawa, M., and Sasakawa, C. (1995a) Contact of Shigella with host cells triggers release of Ipa invasins and is an essential function of invasiveness. EMBO J 14: 2461-2470.
40. Watarai, M., Tobe, T., Yoshikawa, M., and Sasakawa, C. (1995b) Disulphide oxireductase activity of Shigella flexneri is required for release of Ipa proteins and invasion of epithelial cells. Proc Natl Acad Sci USA 92: 4927-4931.
41. Wattiau, P., Bernier, B., Deslée, P., Michiels, T., and Cornelis, G.R. (1994) Individual chaperones required for Yop secretion by Yersinia. Proc Natl Acad Sci USA 91: 10493-10497.
42. Wattiau, P., Woestyn, S., and Cornelis, G.R. (1996) Customized secretion chaperones in pathogenic bacteria. Mol Microbiol 20: 255-262.
43. Zierler, M., and Galán, J.E. (1995) Contact with cultured epithelial cells induces the secretion of the Salmonella typhimurium invasion protein InvJ. Infect Immun 63: 4024-4028.