Recent advances in opioid pharmacology

Current Opinion in Anaesthesiology

Volumn 14, Issue 4, 2001, Pages 405-410

  Dahan, Albert ^a   Kest, Benjamin ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIAMORPHINE; DRUG METABOLITE; GLYCOPROTEIN P; MORPHINE; NOCICEPTIN RECEPTOR; OPIATE;

DRUG EFFECT; DRUG POTENCY; DRUG TOLERANCE; HUMAN; HYPERALGESIA; PAIN; PHARMACODYNAMICS; PRIORITY JOURNAL; PRURITUS; RESPIRATION DEPRESSION; REVIEW; SEX DIFFERENCE;

EID: 0034941977     PISSN: 09527907     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001503-200108000-00005     Document Type: Review

References (55)

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2. Altered nociceptive neuronal circuits after neonatal peripheral inflammation
3. Evidence that postoperative pain is a mediator of the tumor-promoting effects of surgery in rats
4. Pain, plasticity, and premature birth: A prescription for permanent suffering?
5. Gender differences in opioid-mediated analgesia: Animal and human studies
6. Sex differences in thermal nociception and morphine antinociception in rodents depend on genotype
7. Sex-related differences in the antinociceptive effects of opioids: Importance of rat genotype, nociceptive stimulus intensity, and efficacy at the mu opioid receptor
8. Gender affects report of pain and function after arthoscopic anterior cruciate ligament reconstruction
9. Sex differences in morphine analgesia: An experimental study in healthy volunteers
10. Sex differences in morphine-induced ventilatory depression reside within the peripheral chemoreflex loop
11. Does opioid analgesia show a gender preference for females?
12. Brainstem pain modulating circuitry is sexually dimorphic with respect to mu and kappa opioid receptor function
13. A comparison of morphine analgesic tolerance in male and female mice
14. Sex differences in thermoregulation after acute and chronic morphine administration in mice
15. Morphine tolerance after chronic intra-cerebroventricular injection in male and female mice
16. Lack of analgesic activity of morphine-6-glucuronide after short-term intravenous administration in healthy volunteers
17. Preemptive intravenous morphine-6-glucuronide is ineffective for postoperative pain relief
18. Preemptive hyperalgesia, not analgesia?
19. Analgesic action of i.v. morphine-6-glucuronide in healthy volunteers
20. Randomized placebo-controlled trial of the activity of the morphine glucuronides
21. Retention of heroin and morphine-6β-glucuronide analgesia in a new line of mice lacking exon 1 of MOR-1
22. Morphine and morphine-6β-glucuronide-induced feeding are differentially reduced by G-protein α-subunit antisense probes in rats
23. Lack of crosstolerance between morphine and morphine-6-glucuronide as revealed by locomotor activity
24. Opioid effect on breathing frequency and thermogenesis in mice lacking exon 2 of the μ-opioid receptor gene
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26. Agonistic effects of the opioid buprenorphine on the nociceptin/OFQ receptor
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29. Opiate modulating properties of nociceptin/orphanin FQ
30. Effects of supraspinal orphanin FQ/nociceptin
31. The nociceptin/orphanin FQ receptor antagonist
32. Effects of pre-emptively administered nociceptin on the development of thermal hyperalgesia induced by two models of experimental mononeuropathy in the rat
33. Nociceptin/orphanin FQ in spinal nociceptive mechanisms under normal and pathological conditions
34. Nociceptin/orphanin FQ metabolism and bioactive metabolites
35. Anti-nociceptive responses produced by human putative counterpart of nocistatin
36. μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
37. Acute opioid tolerance: Intraoperative remifentanil increases postoperative pain and morphine requirement
38. Long-lasting hyperalgesia induced by fentanyl in rats: Preemptive effect of ketamine
39. Low concentrations of halothane increase response to a noxious thermal stimulus and attenuate the antinociceptive effect of intraventricular but not intrathecal morphine
40. Effects of intrathecal morphine on the ventilatory response to hypoxia
41. The pharmacodynamic effect of remifentanil bolus on ventilatory control
42. Respiratory failure due to combined effects of transdermal fentanyl and epidural bupivacaine/diamorphine following radical nephrectomy
43. The influence of morphine on thermogenesis and ventilatory control in μ-opioid receptor knockout mice
44. Anesthetic potency and influence of morphine and sevoflurane on respiration in μ-opioid receptor knockout mice
45. An experimental itch model in monkeys: Characterization of intrathecal morphine-induced scratching and antinociception
46. A neural pathway for itch
47. Spinothalamic lamina I neurons selectively sensitive to histamine: A central neural pathway for itch
48. Opiate-induced analgesia is increased and prolonged in mice lacking P-glycoprotein
49. Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test
50. Effect of P-glycoprotein modulation on the clinical pharmacokinetic effects of morphine
51. Multicentre randomised controlled trial of nasal diamorphine for analgesia in children and teenagers with clinical fractures
52. Pharmacokinetics and pharmacodynamics of inhaled versus intravenous morphine in healthy volunteers
53. The combined effects of N-type calcium channel blockers and morphine on Aδ versus C fiber mediated antinociception
54. Gabapentin enhances the analgesic effect of morphine in healthy volunteers
55. Glycyl-glutamine inhibits the respiratory depression, but not the antinociception, produced by morphine