Molecular basis of oncogenesis;Bases moléculaires de l'oncogenèse

Annales de Biologie Clinique

Volumn 59, Issue 4, 2001, Pages 393-402

  Paul, S ^a   Regulier E ^a  

^a TRANSGENE S A   (France)

Author keywords

Angiogenesis; Apoptosis; Cancer; Metastasis; Tumor

Indexed keywords

BETA CATENIN; CANCER GROWTH FACTOR; CASPASE; CD36 ANTIGEN; CELL ADHESION MOLECULE; CYTOCHROME C; DNA; DNA POLYMERASE; ENDOSTATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR; IMMUNOGLOBULIN; INTEGRIN; MITOGEN ACTIVATED PROTEIN KINASE; NERVE CELL ADHESION MOLECULE; PLATELET DERIVED GROWTH FACTOR; PROTEIN BCL 2; PROTEIN P130; PROTEIN P15; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN; SOMATOMEDIN B; SOMATOMEDIN C; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; UVOMORULIN; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; CANCER; CARCINOGENESIS; CELL FUNCTION; CELL PROLIFERATION; CELL TRANSFORMATION; HOMEOSTASIS; HUMAN; METASTASIS; NEOPLASM; NEOVASCULARIZATION (PATHOLOGY); REVIEW;

ANIMALS; CELL PHYSIOLOGY; CELL TRANSFORMATION, NEOPLASTIC; HOMEOSTASIS; HUMANS; MODELS, BIOLOGICAL; NEOPLASM METASTASIS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC;

EID: 0034927874     PISSN: 00033898     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (54)

1. Cancer burden in Europe for 1990: Can we predict the figures for the year 2000?
2. Oncogene products as therapeutic targets for cancer
3. The hallmarks of cancer
4. Lessons from hereditary colorectal cancer
5. Creation of human tumour cells with defined genetic elements
6. Angiogenesis and apoptosis are cellular parameters of neoplastic progression in transgenic mouse models of tumorigenesis
7. Mortality and immortality at the cellular level. A review
8. Role of telomerase in cellular proliferation and cancer
9. Extension of life-span by introduction of telomerase into normal human cells
10. Integrin signaling
11. Oncoprotein networks
12. Ras-a versatile cellular switch
13. Two MAD tails: What the recent knockouts of Mad1 and Mxi1 tell us about the MYC/MAX/MAD network
14. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
15. The retinoblastoma protein and cell cycle control
16. TGF-beta stimulation and inhibition of cell proliferation: New mechanistic insights
17. The viral oncoprotein E1A blocks transforming growth factor beta-mediated induction of p21/WAF1/Cip1 and p15/INK4B
18. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
19. The INK4a/ARF tumor suppressor: One gene-two products-two pathways
20. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
21. Mechanisms of angiogenesis
22. Vasculogenesis
23. Addressing tumor blood vessels
24. Antiangiogenic therapy of transgenic mice impairs de novo tumor growth
25. Manipulating angiogenesis. From basic science to the bedside
26. Recent advances in research on multistage tumorigenesis
27. The role of fibroblast growth factors in tumour progression and angiogenesis
28. Src-related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells
29. Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
30. Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
31. Target molecules for anti-angiogenic therapy: From basic research to clinical trials
32. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1 alpha
33. An in vivo function for the transforming Myc protein: Elicitation of the angiogenic phenotype
34. Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity
35. The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin
36. The war on cancer
37. Signa transduction and signal modulation by cell adhesion receptors: The role of integrins cadherins, immunoglobulin-cell adhesion molecules, and selectins
38. The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
39. The neural cell adhesion molecule NCAM in multiple myeloma
40. Neural cell adhesion molecule (N-CAM) in gastrointestinal neoplasias
41. Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells
42. ECM signalling: Orchestrating cell behaviour and misbehaviour
43. Matrix metalloproteinases in angiogenesis: A moving target for therapeutic intervention
44. Extrinsic regulators of epithelial tumor progression: Metalloproteinases
45. Tumor-induced immune dysfunction
46. Caspases: Enemies within
47. Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer
48. Structure and function of the p53 tumor suppressor gene: Clues for rational cancer therapeutic strategies
49. The mutation rate and cancer
50. Cancer biology
51. Rebuilding the road to cancer
52. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis