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Volumn 19, Issue 2, 2001, Pages 152-171

Carvedilol: Molecular and cellular basis for its multifaceted therapeutic potential

Author keywords

Adrenoceptor blockade; Antioxidant effects; Cardiac ion channels; Cardiovascular protection; Carvedilol

Indexed keywords

1 [3 HYDROXYCARBAZOLYL (4) OXY] 3 [(2 METHOXYPHENOXY)ETHYLAMINO]PROPAN 2 OL; ACETYLSALICYLIC ACID; ALPHA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CALCIUM CHANNEL; CARDIOVASCULAR AGENT; CARVEDILOL; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; DRUG METABOLITE; HEPARIN; MEMBRANE RECEPTOR; METOPROLOL; NEUROHORMONE; NITRATE; POTASSIUM CHANNEL; REACTIVE OXYGEN METABOLITE; SB 209995; UNCLASSIFIED DRUG; VERAPAMIL;

EID: 0034909760     PISSN: 08975957     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1527-3466.2001.tb00061.x     Document Type: Review
Times cited : (112)

References (119)
  • 1
    • 0031583760 scopus 로고    scopus 로고
    • Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: Meta-analysis of individual data from 6500 patients in randomized trials
    • (1997) Lancet , vol.350 , pp. 1417-1424
  • 3
    • 0029006613 scopus 로고
    • Effects of carvedilol, a vasodilator-β-blocker in patients with congestive heart failure due to ischemic heart disease
    • (1995) Circulation , vol.92 , pp. 212-218
  • 4
    • 0031050642 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischemic heart disease
    • (1997) Lancet , vol.349 , pp. 375-380
  • 8
    • 0020078179 scopus 로고
    • A randomized trial of propranolol in patients with acute myocardial infarction. I. Mortality results
    • (1982) JAMA , vol.247 , pp. 1707-1714
  • 10
    • 0027480506 scopus 로고
    • Pathophysiologic and pharmacologic rationales for clinical management of chronic heart failure with β-blocking agents
    • (1993) Am J Cardiol , vol.71
    • Bristow, M.R.1
  • 18
    • 0028092116 scopus 로고
    • A randomized trial of β-blockade in heart failure: The Cardiac Insufficiency Bisoprolol Study (CIBIS)
    • (1994) Circulation , vol.90 , pp. 1765-1773
  • 42
    • 0024463514 scopus 로고
    • Effects of carvedilol on left ventricular function and arrhythmias during repeated short-time myocardial ischemia in experimental pigs
    • (1989) Z Kardiol , vol.78 , Issue.SUPPL. 3 , pp. 7-15
    • Hoher, M.1    Friedrich, M.2    Sommer, T.3
  • 43
    • 0025164907 scopus 로고
    • Class III antiarrhythmic agents have a lot of potential but a long way to go. Reduced effectiveness and dangers of reverse use dependence
    • (1990) Circulation , vol.81 , pp. 686-690
    • Hondeghem, L.M.1    Snyders, D.J.2
  • 45
    • 84888827980 scopus 로고
    • Randomized trial of intravenous atenolol among 16,027 cases of suspected acute myocardial infarction: ISIS-1
    • (1986) Lancet , vol.2 , pp. 57-66
  • 58
    • 0030430050 scopus 로고    scopus 로고
    • Carvedilol, a new β-adrenoceptor blocker and a free radical scavenger, attenuates myocardial ischemia-reperfusion injury in hypercholesterolemic rabbits
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 128-136
    • Ma, X.L.1    Yue, T.L.2    Lopez, B.L.3
  • 72
    • 0019459311 scopus 로고
    • Timolol induced reduction in mortality and reinfarction in patients surviving acute myocardial infarction
    • (1981) N Engl J Med , vol.304 , pp. 801-807
  • 77
    • 0034091336 scopus 로고    scopus 로고
    • Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wildtype and beta(3)-adrenoceptor knockout mice
    • (2000) Br J Pharmacol , vol.130 , pp. 747-758
    • Oostendorp, J.1    Preitner, F.2    Moffatt, J.3
  • 79
    • 0022384823 scopus 로고
    • Sudden unexpected death in patients with congestive heart failure: A second frontier
    • (1985) Circulation , vol.72 , pp. 681-685
    • Packer, M.1
  • 80
    • 0026695294 scopus 로고
    • The neurohormonal hypothesis: A theory to explain the mechanism of disease progression in heart failure
    • (1992) J Am Coll Cardiol , vol.20 , pp. 248-254
    • Packer, M.1
  • 86
    • 0029921523 scopus 로고    scopus 로고
    • The preventative effects of vasodilating β-blockers in cardiovascular disease
    • (1996) Eur Heart J , vol.17 , Issue.SUPPL. B , pp. 30-38
    • Raftery, E.B.1
  • 88
    • 0026099412 scopus 로고
    • Immediate versus deferred β-blockade following thrombolytic therapy in patients with acute myocardial infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI) II-B study
    • (1991) Circulation , vol.83 , pp. 422-437
    • Roberts, R.1    Rogers, W.J.2    Mueller, H.S.3
  • 89
  • 97
    • 0034603769 scopus 로고    scopus 로고
    • Carvedilol for prevention of restenosis after directional coronary atherectomy: Final results of the European Carvedilol Atherectomy Restenosis (EUROCARE) Trial
    • (2000) Circulation , vol.101 , pp. 1512-1518
    • Serruys, P.W.1    Foley, D.P.2    Hofling, B.3
  • 98
    • 0032546405 scopus 로고    scopus 로고
    • Antiarrhythmic drugs: A reorientation in light of recent developments in the control of disorders of rhythm
    • (1998) Am J Cardiol , vol.81
    • Singh, B.N.1
  • 102
    • 0019977111 scopus 로고
    • Haemodynamic advantage of combined alpha-blockade and beta-blockade over beta-blockade alone in patients with coronary heart disease
    • (1982) Br Med J , vol.285 , pp. 325-327
    • Taylor, S.H.1    Silke, B.2    Nelson, G.I.C.3
  • 103
    • 0021839784 scopus 로고
    • Metoprolol in acute myocardial infarction (MIAMI): A randomized placebo controlled international trial
    • (1985) Eur Heart J , vol.61 , pp. 199-226
  • 117
    • 0032498614 scopus 로고    scopus 로고
    • Possible involvement of stress-activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/reperfusion-induced cardiomyocyte apoptosis by carvedilol
    • (1998) Circ Res , vol.82 , pp. 166-174
    • Yue, T.-L.1    Ma, X.L.2    Wang, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.