Carvedilol and lacidipine prevent cardiac hypertrophy and endothelin-1 gene overexpression after aortic banding

Hypertension

Volumn 34, Issue 6, 1999, Pages 1197-1201

  Massart, Pierre Emmanuel ^a   Donckier, Julian ^b   Kyselovic, Jan ^a   Godfraind, Théophile ^a   Heyndrickx, Guy R ^a   Wibo, Maurice ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY HOSPITAL OF MONT GODINNE   (Belgium)

Author keywords

Carvedilol; Endothelin; Hypertension, experimental; Hypertrophy, left ventricular; Lacidipine; actin

Indexed keywords

ALPHA ACTIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CARVEDILOL; ENDOTHELIN 1; LACIDIPINE; MESSENGER RNA;

ANIMAL MODEL; ARTICLE; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DRUG EFFECT; EXPERIMENTAL MODEL; GENE OVEREXPRESSION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HEART VENTRICLE HYPERTROPHY; HEMODYNAMIC PARAMETERS; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0033405130     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.34.6.1197     Document Type: Article

References (39)

1. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411-415.
2. Shubeita HE, McDonough PM, Harris AN, Knowlton KU, Glembotski CC, Brown JH, Chien KR. Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes: a paracrine mechanism for myocardial cell hypertrophy. J Biol Chem. 1990;265:20555-20562.
3. Ito H, Hirata Y, Hiroe M, Tsujino M, Adachi S, Takamoto T, Nitta M, Taniguchi K, Marumo F. Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes. Circ Res. 1991;69:209-215.
4. Ito H, Hirata Y, Adachi S, Tanaka M, Tsujino M, Koike A, Nogami A, Marumo F, Hiroe M. Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes. J Clin Invest. 1993;92:398-403.
5. Yamazaki T, Komuro I, Kudoh S, Zou Y, Shiojima I, Hiroi Y, Mizuno T, Maemura K, Kurihara H, Aikawa R, Takano H, Yazaki Y. Endothelin-1 is involved in mechanical stress-induced cardiomyocyte hypertrophy. J Biol Chem. 1996;271:3221-3228.
6. A receptor antagonist blocks cardiac hypertrophy provoked by hemodynamic overload. Circulation. 1994;89: 2198-2203.
7. Okada M, Kobayashi M, Maruyama H, Takahashi R, Ikemoto F, Yano M, Nishikibe M. Effects of a selective endothelin A-receptor antagonist, BQ-123. in salt-loaded stroke-prone spontaneously hypertensive rats. Clim Exp Pharmacol Physiol. 1995;22:763-768.
8. Stasch J-P, Hirth-Dietrich C, Frobel K, Wegner M. Prolonged endothelin blockade prevents hypertension and cardiac hypertrophy in stroke-prone spontaneously hypertensive rats. Am J Hypertens. 1995;8:1128-1134.
9. Fujita K, Matsumara Y, Miyazaki Y, Takaoka M, Morimoto S. Effects of the endothelin ETA-receptor antagonist FR139317 on development of hypertension and cardiovascular hypertrophy in deoxycorticosterone acetate-salt hypertensive rats. Jpn J Pharmacol. 1996;70:313-319.
10. Karam H, Heudes D, Hess P, Gonzales MF, Löffler BM, Clozel M, Clozel J-P. Respective role of humoral factors and blood pressure in cardiac remodeling of DOCA hypertensive rats. Cardiovasc Res. 1996; 31:287-295.
11. A receptor blockade attenuates cardiac hypertrophy independently of blood pressure effects in renovascular hypertensive rats. Hypertension 1999;33:954-960.
12. Herizi A, Jover B, Bouriquet N, Mimran A. Prevention of the cardiovascular and renal effects of angiotensin II by endothelin blockade. Hypertension. 1998;31[pt 1]:10-14.
13. B receptor antagonist. Circulation. 1996;93:2068-2079.
14. Yue T-L, Cheng H-Y, Lysko PG, McKenna PJ, Feuerstein R, Gu JL, Lysko KA, Davis LL, Feuerstein G. Carvedilol, a new vasodilator and beta adrenoceptor antagonist, is an antioxidant and free radical scavenger. J Pharmacol Exp Ther. 1992;263:92-98.
15. Ruffolo RR, Feuerstein GZ. Pharmacology of carvedilol: rationale for use in hypertension, coronary artery disease, and congestive heart failure. Cardiovasc Drug Ther. 1997;11:247-256.
16. Saijonmaa O, Metsarinne K, Fyhrquist F. Carvedilol and its metabolites suppress endothelin-1 production in human endothelial cell culture. Blood Press. 1997;6:24-28.
17. Ohlstein EH, Arleth AJ, Storer B, Romanic AM. Carvedilol inhibits endothelin-1 biosynthesis in cultured human coronary artery endothelial cells. J Mol Cell Cardiol. 1998;30:167-173.
18. Barone FC, Campbell Jr WG, Nelson AH, Feuerstein GZ. Carvedilol prevents severe hypertensive cardiomyopathy and remodeling. J Hypertens. 1998;16:871-884.
19. Feron O, Salomone S, Godfraind T. Action of the calcium channel blocker lacidipine on cardiac hypertrophy and endothelin-1 gene expression in stroke-prone hypertensive rats. Br J Pharmacol. 1996;118:659-664.
20. Kyselovic J, Morel N, Wibo M, Godfraind T. Prevention of salt-dependent cardiac remodeling and enhanced gene expression in stroke-prone hypertensive rats by the long-acting calcium channel blocker lacidipine. J Hypertens. 1998;16:1515-1522.
21. Yorikane R, Sakai S, Miyauchi T, Sakurai T, Sugishita Y, Goto K. Increased production of endothelin-1 in the hypertrophied rat heart due to pressure overload. FEBS Lett. 1993;332:31-34.
22. Jouannot P, Hatt P, Rat myocardial mechanics during pressure-induced hypertrophy development and reversal. Am J Physiol. 1975;229:355-364.
23. Donckier J, Hanet C, Berbinschi AC, Galanti L, Robert A, Van Mechelen H, Pouleur H, Ketelslegers JM. Cardiovascular and endocrine effects of endothelin-1 at pathophysiological and pharmacological plasma concentrations in conscious dogs. Circulation. 1991;84:2476-2484.
24. Heller LJ, Opsahl JA, Wemsing SE, Saxena R, Katz SA. Myocardial and plasma renin-angiotensinogen dynamics during pressure-induced cardiac hypertrophy. Am J Physiol. 1998;274:R849-R856.
25. Arai M, Yoguchi A, Iso T, Takahashi T, Imai S, Murata K, Suzuki T. Endothelin-1 and its binding sites are upregulated in pressure overload cardiac hypertrophy. Am J Physiol. 1995;268:H2084-H2091.
26. Yamazaki T, Yazaki Y. Is there major involvement of the renin-angiotensin system in cardiac hypertrophy? Circ Res. 1997;81:639-642.
27. Baker KM, Chernin MI, Wixson SK, Aceto JF. Renin-angiotensin system involvement in pressure-overload cardiac hypertrophy in rats. Am J Physiol. 1990;259:H324-H332.
28. 1 expression. Hypertension. 1994;23:587-592.
29. Harada M, Itoh H, Nakagawa O, Ogawa Y, Miyamoto Y, Kuwahara K, Ogawa E, Igaki T, Yamashita J, Masuda I, Yoshimasa T, Tanaka I, Saito Y, Nakao K. Significance of ventricular myocytes and nonmyocytes interaction during cardiocyte hypertrophy: evidence for endothelin-1 as a paracrine hypertrophie factor from cardiac nonmyocytes. Circulation. 1997;96:3737-3744.
30. Pönicke K, Heinroth-Hoffmann I, Becker K, Brodde O-E. Trophic effect of angiotensin II in neonatal rat cardiomyocytes: role of endothelin-1 and non-myocyte cells. Br J Pharmacol. 1997;121:118-124.
31. 1 and endothelin-1 from fibroblasls. Cardiovasc Res. 1998;40:352-363.
32. Bouloumié A, Bauersachs J, Linz W, Schölkens BA, Wiemer G, Fleming I, Busse R. Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production. Hypertension. 1997;30:934-941.
33. De Keulenaar GW, Andries LJ, Sys SU, Brutsaert DL. Endothelin-mediated positive inotropic effect induced by reactive oxygen species in isolated cardiac muscle. Circ Res. 1995;76:878-884.
34. Van Amsterdam FTM, Roveri A, Maiorino M, Ratti E, Ursini F. Lacidipine: a dihydropyridine calcium antagonist with antioxidant activity. Free Radic Biol Med. 1992;12:183-187.
35. Cominacini L, Garbin U, Fratta Pasini A, Davoli A, Campagnola M, Pastorino AM, Gaviraghi G, Lo Cascio V. Oxidized low-density lipoprotein increases the production of intracellular reactive oxygen species in endothelial cells: inhibitory effect of lacidipine. J Hypertens. 1998;16:1913-1919.
36. Emori T, Hirata Y, Ohta K, Kanno K, Eguchi S, Imai T, Shichiri M, Marumo F. Cellular mechanism of endothelin-1 release by angiotensin and vasopressin. Hypertension. 1991;18:165-170.
37. Emori T, Hirata Y, Imai T, Ohta K, Kanno K, Eguchi S, Marumo F. Cellular mechanism of thrombin on endothelin-1 biosynthesis and release in bovine endothelial cell. Biochem Pharmacol. 1992;44:2409-2411.
38. Himmel HM, Whorton AR, Strauss HC. Intracellular calcium, currents, and stimulus-response coupling in endothelial cells. Hypertension. 1993; 21:112-127.
39. Izumo S, Nadal-Ginard B, Mahdavi V. Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload. Proc Natl Acad Sci U S A. 1988;85:339-343.