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Volumn 8, Issue 4, 2001, Pages 224-230

Pathogenesis and treatment of Ph+ leukemia: Recent insights from mouse models

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN;

EID: 0034889951     PISSN: 10656251     EISSN: None     Source Type: Journal    
DOI: 10.1097/00062752-200107000-00008     Document Type: Review
Times cited : (10)

References (56)
  • 6
    • 0035282901 scopus 로고    scopus 로고
    • Activity of the farnesyl protein transferase inhibitor SCH66336 against BCR/ABL-induced murine leukemia and primary cells from patients with chronic myeloid leukemia
    • (2001) Blood , vol.97 , pp. 1404-1412
    • Peters, D.G.1    Hoover, R.R.2    Gerlach, M.J.3
  • 9
  • 13
    • 13344262695 scopus 로고    scopus 로고
    • Normal and leukemic SCID- repopulating cells (SRC) coexist in the bone marrow and peripheral blood from CML patients in chronic phase, whereas leukemic SRC are detected in blast crisis
    • (1996) Blood , vol.87 , pp. 1539-1548
    • Sirard, C.1    Lapidot, T.2    Vormoor, J.3
  • 14
    • 0032529306 scopus 로고    scopus 로고
    • The kinetics and extent of engraftment of chronic myelogenous leukemia cells in non-obese diabetic/severe combined immunodeficiency mice reflect the phase of the donor's disease: An in vive model of chronic myelogenous leukemia biology
    • (1998) Blood , vol.92 , pp. 1390-1396
    • Dazzi, F.1    Capelli, D.2    Hasserjian, R.3
  • 15
    • 0032055156 scopus 로고    scopus 로고
    • High level engraftment of NOD/SCID mice by primitive normal and leukemic hematopoietic cells from patients with chronic myeloid leukemia in chronic phase
    • (1998) Blood , vol.91 , pp. 2406-2414
    • Wang, J.C.Y.1    Lapidot, T.2    Cashman, J.D.3
  • 16
    • 0031982855 scopus 로고    scopus 로고
    • Establishment of a reproducible model of chronic-phase chronic myeloid leukemia in NOD/SCID mice using blood-derived mononuclear or CD34+ cells
    • (1998) Blood , vol.91 , pp. 630-640
    • Lewis, I.D.1    McDiarmid, L.A.2    Samels, L.M.3
  • 17
    • 0033568250 scopus 로고    scopus 로고
    • Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia
    • (1999) Blood , vol.94 , pp. 2056-2064
    • Holyoake, T.1    Jiang, X.2    Eaves, C.3
  • 19
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 20
    • 0035166003 scopus 로고    scopus 로고
    • The Src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase
    • (2001) Blood , vol.97 , pp. 4-13
    • Roumiantsev, S.1    De Aos, I.2    Varticovski, L.3
  • 26
    • 0026666779 scopus 로고
    • Clonal evolution in a myeloid cell line transformed to interleukin-3 independent growth by retroviral transduction and expression of p210bcr/abl
    • (1992) Blood , vol.80 , pp. 1788-1797
    • Laneuville, P.1    Sun, G.2    Timm, M.3
  • 27
    • 0033614396 scopus 로고    scopus 로고
    • Mutator phenotype of BCR-ABL transfected Ba/F3 cell lines and its association with enhanced expression of DNA polymerase beta
    • (1999) Oncogene , vol.18 , pp. 2676-2680
    • Canitrot, Y.1    Lautier, D.2    Laurent, G.3
  • 29
    • 0029131231 scopus 로고
    • BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: A mechanism of resistance to multiple anticancer agents
    • (1995) Blood , vol.86 , pp. 1148-1158
    • Bedi, A.1    Barber, J.P.2    Bedi, G.C.3
  • 36
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the BCR-ABL tyresine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome
    • (2001) N Engl J Med , vol.344 , pp. 1084-1086
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3
  • 38
    • 0034651959 scopus 로고    scopus 로고
    • Acquired loss of p53 induces biastic transformation in p210(bcr/abl)-expressing hematopoietic cells: A transgenic study for blast crisis of human CML
    • (2000) Blood , vol.95 , pp. 1144-1150
    • Honda, H.1    Ushijima, T.2    Wakazono, K.3
  • 40
    • 0034652159 scopus 로고    scopus 로고
    • Regulated expression of p210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1737-1742
    • Era, T.1    Witte, O.N.2
  • 42
    • 0032533257 scopus 로고    scopus 로고
    • Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow
    • (1998) Blood , vol.92 , pp. 3780-3792
    • Pear, W.S.1    Miller, J.P.2    Xu, L.3
  • 43
    • 0032533620 scopus 로고    scopus 로고
    • Bcr-Abl efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: A novel model for chronic myelogenous leukemia
    • (1998) Blood , vol.92 , pp. 3829-3840
    • Zhang, X.1    Ren, R.2
  • 44
    • 0033519238 scopus 로고    scopus 로고
    • The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity
    • (1999) J Exp Med , vol.189 , pp. 1399-1412
    • Li, S.1    Ilaria, R.L.2    Million, R.P.3
  • 45
    • 0035052161 scopus 로고    scopus 로고
    • Retroviral transduction models of Ph+ leukemia: Advantages and limitations for modeling human hematological malignancies in mice
    • (2001) Blood Cells Mol Dis , vol.27 , pp. 201-205
    • Van Etten, P.A.1
  • 46
    • 0034665676 scopus 로고    scopus 로고
    • Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl- and bcr/abl-induced transformation are independent of STAT5
    • (2000) Blood , vol.96 , pp. 2277-2283
    • Sexl, V.1    Piekorz, R.2    Moriggl, R.3
  • 49
    • 0035282909 scopus 로고    scopus 로고
    • Interleukin-3 and granulocyte-macrophage colony-stimulating factor are not required for induction of chronic myeloid leukemia-like myeloproliferatlve disease in mice by BCR/ABL
    • (2001) Blood , vol.97 , pp. 1442-1450
    • Li, S.1    Gillessen, S.2    Tomasson, M.H.3
  • 51
    • 0034661522 scopus 로고    scopus 로고
    • The Grb2 binding site is required for induction of chronic myeloid leukemia-like disease in mice by the Bcr/Abl tyrosine kinase
    • (2000) Blood , vol.96 , pp. 664-670
    • Million, R.P.1    Van Etten, P.A.2
  • 54
    • 0034649515 scopus 로고    scopus 로고
    • Bcr-Abl has a greater intrinsic capacity than v-Abl to induce the neoplastic expansion of myeloid progenitor cells
    • (2000) Oncogene , vol.19 , pp. 6286-6296
    • Gross, A.W.1    Ren, R.2
  • 56
    • 0035174344 scopus 로고    scopus 로고
    • The SH2 domain of Bcr-Abl is not required to induce a murine myeloproliferative disease; however, SH2 signaling influences disease latency and phenotype
    • (2001) Blood , vol.97 , pp. 277-287
    • Zhang, X.1    Wong, R.2    Hao, S.X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.