Efficacy of the bystander effect in the herpes simplex virus thymidine kinase-mediated gene therapy is influenced by the expression of connexin43 in the target cells

Cancer Gene Therapy

Volumn 8, Issue 6, 2001, Pages 414-420

  Namba, Hiroki ^a   Iwadate, Yasuo ^b   Kawamura, Kiyoko ^c   Sakiyama, Shigeru ^c   Tagawa, Masatoshi ^c  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c CHIBA CANCER CENTER   (Japan)

Author keywords

Bystander effect; Cell based gene therapy; Connexin; Ganciclovir; Glioma; Herpes simplex virus thymidine kinase

Indexed keywords

CONNEXIN 43; GANCICLOVIR; GENE PRODUCT; THYMIDINE KINASE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; GENE THERAPY; GENETIC TRANSDUCTION; GLIOMA CELL; HERPES SIMPLEX VIRUS; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RAT; TARGET CELL;

ANIMALS; ANTIVIRAL AGENTS; BLOTTING, WESTERN; CONNEXIN 43; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GANCICLOVIR; GENE THERAPY; GENE TRANSFER TECHNIQUES; MICE; MICE, INBRED BALB C; MICE, NUDE; RATS; SIMPLEXVIRUS; THYMIDINE KINASE; TRANSDUCTION, GENETIC; TUMOR CELLS, CULTURED;

ANIMALIA; HERPES; MUS MUSCULUS; SIMPLEXVIRUS;

EID: 0034887138     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700317     Document Type: Article

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