Sampling of complementing self-antigen pools by thymic stromal cells maximizes the scope of central T cell tolerance

European Journal of Immunology

Volumn 31, Issue 8, 2001, Pages 2476-2486

  Klein, Ludger ^a,b   Roettinger, Bernd ^a   Kyewski, Bruno ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

Ectopic gene expression; T cell deletion; T cell tolerance; Thymic antigen presentation; Thymic epithelial cell

Indexed keywords

CD4 ANTIGEN; CELL ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; CELL SELECTION; CONTROLLED STUDY; HEMATOPOIETIC CELL; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE DEPLETION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SAMPLING; STROMA CELL; T LYMPHOCYTE; THYMUS;

ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; APOPTOSIS; AUTOANTIGENS; BONE MARROW TRANSPLANTATION; C-REACTIVE PROTEIN; CD4-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; EPITHELIAL CELLS; FLOW CYTOMETRY; HUMANS; IMMUNE TOLERANCE; IN SITU HYBRIDIZATION; MICE; MICE, INBRED STRAINS; MICE, TRANSGENIC; RADIATION CHIMERA; RNA, MESSENGER; STROMAL CELLS; THYMUS GLAND; TRANSGENES;

EID: 0034857910     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200108)31:8<2476::AID-IMMU2476>3.0.CO;2-T     Document Type: Article

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