Therapeutic potential of PKC inhibitors in painful diabetic neuropathy

Expert Opinion on Investigational Drugs

Volumn 10, Issue 9, 2001, Pages 1653-1664

  Kamei, J ^a   Mizoguchi, H ^a   Narita, M ^a   Tseng, L F ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Diabetes mellitus; Diabetic neuropathy; Neuropathic pain; Protein kinase C; Tetrodotoxin resistant sodium channel

Indexed keywords

4 CARBOXYPHENYLGLYCINE; ALDOSE REDUCTASE INHIBITOR; AMINO ACID; CALPHOSTIN C; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIZOCILPINE; FORMALDEHYDE; FORSKOLIN; GANGLIOSIDE GM1; GLUTAMIC ACID; INOSITOL; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEUROKININ 1 RECEPTOR; NEUROTRANSMITTER; NICERITROL; PHORBOL 13 ACETATE 12 MYRISTATE; PHORBOL DIBUTYRATE; PHORBOL ESTER; POLYOL; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RUBOXISTAURIN; SODIUM; SODIUM CHANNEL; STREPTOZOCIN; SUBSTANCE P; TACHYKININ; TETRODOTOXIN; UNINDEXED DRUG; VANILLOID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONTROLLED STUDY; DIABETIC NEUROPATHY; DISEASE MODEL; DRUG EFFICACY; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; HUMAN; HYPERALGESIA; HYPERGLYCEMIA; HYPERSENSITIVITY; INSULIN DEPENDENT DIABETES MELLITUS; KNOCKOUT MOUSE; MOUSE; NERVE CELL; NERVE LIGATION; NOCICEPTION; NONHUMAN; PERIPHERAL NERVE INJURY; REVIEW; SCIATIC NERVE; SENSITIZATION; SPINAL CORD DORSAL HORN; STREPTOZOCIN DIABETES; TAIL FLICK TEST; THERMAL STIMULATION; TISSUE INJURY; TOUCH; TRIGEMINAL NERVE;

ANIMALS; DIABETIC NEUROPATHIES; ENZYME INHIBITORS; HUMANS; PAIN; PROTEIN KINASE C;

EID: 0034845697     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.10.9.1653     Document Type: Review

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