Involvement of spinal protein kinase Cγ in the attenuation of opioid μ-receptor-mediated G-protein activation after chronic intrathecal administration of [d-Ala2,N-MePhe4,Gly-Ol5]enkephalin

Journal of Neuroscience

Volumn 21, Issue 11, 2001, Pages 3715-3720

  Narita, Minoru ^a,b   Mizoguchi, Hirokazu ^b   Narita, Michiko ^b   Nagase, Hiroshi ^b,c   Suzuki, Tsutomu ^a   Tseng, Leon F ^b  

^a HOSHI UNIVERSITY   (Japan)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c TORAY INDUSTRIES INC   (Japan)

Author keywords

G protein; Phosphorylation; Protein kinase C; Spinal cord; Tolerance; opioid receptor

Indexed keywords

3 [8 [(DIMETHYLAMINO)METHYL] 6,7,8,9 TETRAHYDROPYRIDO[1,2 A]INDOL 10 YL] 4 (1 METHYL 1H INDOL 3 YL) 1H PYRROLE 2,5 DIONE; ENDOMORPHIN 1; ENDOMORPHIN 2; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; MU OPIATE RECEPTOR; PROTEIN KINASE C INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; DESENSITIZATION; DRUG EFFECT; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; MOUSE; NONHUMAN; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SECOND MESSENGER; SIGNAL TRANSDUCTION; SPINAL CORD; STIMULUS RESPONSE;

EID: 0035370725     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-11-03715.2001     Document Type: Article

References (4)

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