Fanconi anemia protein, FANCG, is a phosphoprotein and is upregulated with FANCA after TNF-α treatment

Biochemical and Biophysical Research Communications

Volumn 281, Issue 2, 2001, Pages 347-351

  Futaki, Makoto ^a   Watanabe, Shinji ^a   Kajigaya, Sachiko ^a   Liu, Johnson M ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Fanconi anemia; NF B; Phosphorylation; Protein complex; Protein regulation; TNF

Indexed keywords

FANCONI ANEMIA GROUP A PROTEIN; FANCONI ANEMIA GROUP G PROTEIN; FANCONI ANEMIA PROTEIN; GENE PRODUCT; I KAPPA B KINASE 2; INHIBITOR PROTEIN; PHOSPHOPROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; FANCONI ANEMIA; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

EID: 0034813499     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.4359     Document Type: Article

References (22)

1. Fanconi anemia and novel strategies for therapy
2. Cloning of cDNA for Fanconi’s anemia by functional complementation
3. Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA
4. Positional cloning of Fanconi anemia group A gene
5. The Fanconi anaemia group G gene FANCG is identical with XRCC9
6. The Fanconi anemia gene FANCF encodes a novel protein with homology to ROM
7. Isolation of a cDNA representing the Fanconi anemia complementation group E gene
8. DNA damage-induced association of the Fanconi anemia protein, FANCD2, with BRCA1 nuclear foci
9. Molecular biology of Fanconi anemia: Implications for diagnosis and therapy
10. Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex
11. A physical complex of the Fanconi anemia proteins FANCG/XRCC9 and FANCA
12. The Fanconi anemia proteins FANCA and FANCG stabilize each other and promote the nuclear accumulation of the Fanconi anemia complex
13. The Fanconi anemia pathway requires FAA phosphorylation and FAA/FAC unclear accumulation
14. Abnormal lymphokine production: A novel feature of the genetic disease Fanconi anemia. II. In vitro and in vivo spontaneous overproduction of tumor necrosis factor α
15. Tumor necrosis factor-α and CD95 ligation suppress erythropoiesis in Fanconi anemia C gene knockout mice
16. Multiple inhibitory cytokines induce deregulated progenitor growth and apoptosis in hematopoietic cells from Fac-/- mice
17. Characterization of the CIN85 adaptor protein and identification of components involved in CIN85 complexes
18. Nuclear factor-κB-a pivotal transcription factor in chronic inflammatory diseases
19. The IKK complex: An integrator of all signals that activate NF-kappaB?
20. The role of oxygen metabolism for the pathological phenotype of Fanconi anemia
21. The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG
22. Kinase cascades regulating entry into apoptosis