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Volumn 9, Issue 11, 2001, Pages 2929-2935
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Synthesis of 2,4-Diamino-6-(thioarylmethyl)pyrido[2,3-d]pyrimidines as dihydrofolate reductase inhibitors
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Author keywords
[No Author keywords available]
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Indexed keywords
2,4 DIAMINO 6 [(1 NAPHTHYLTHIO)METHYL]PYRIDO[2,3 D]PYRIMIDINE;
2,4 DIAMINO [(PHENYLTHIO)METHYL][2,3 D]PYRIMIDINE DERIVATIVE;
ANTIMYCOBACTERIAL AGENT;
ANTIPROTOZOAL AGENT;
DIHYDROFOLATE REDUCTASE;
DIHYDROFOLATE REDUCTASE INHIBITOR;
PYRIDO[2,3 D]PYRIMIDINE DERIVATIVE;
PYRIMETHAMINE;
UNCLASSIFIED DRUG;
2,4 DIAMINO 6 [(1 NAPHTHYLTHIOL)METHYL]PYRIDO[2,3 D]PYRIMIDINE;
2,4 DIAMINO 6 [(2 NAPHTHYLTHIOL)METHYL]PYRIDO[2,3 D]PYRIMIDINE;
2,4 DIAMINO 6 [(3',4' DIMETHOXYPHENYLTHIO)METHYL]PYRIDO[2,3 D]PYRIMIDINE;
2,4 DIAMINO 6 [(3',5' DICHLOROPHENYLTHIO)METHYL]PYRIDO[2,3 D]PYRIMIDINE;
2,4 DIAMINO 6 [(PHENYLTHIO)METHYL]PYRIDO[2,3 D]PYRIMIDINE;
2,4 DIAMINO 6 BROMOMETHYLPYRIDO[2,3 D]PYRIMIDINE;
2,4 DIAMINOPYRIDO[2,3 D]PYRIMIDINE DERIVATIVE;
2.4 DIAMINO 6 [(2',5' DICHLOROPHENYLTHIO)METHYL]PYRIDO[2,3 D]PYRIMIDINE;
EPIROPRIM;
NAPHTHYL GROUP;
PIRITREXIM;
THIOL DERIVATIVE;
TRIMETHOPRIM;
TRIMETREXATE;
ARTICLE;
DRUG SYNTHESIS;
ENZYME INHIBITION;
IN VITRO STUDY;
LIVER;
MASS SPECTROMETRY;
NONHUMAN;
NUCLEAR MAGNETIC RESONANCE;
PNEUMOCYSTIS CARINII;
TOXOPLASMA GONDII;
TUBERCULOSIS;
ANIMAL CELL;
ANIMAL MODEL;
ANIMAL TISSUE;
ANTIBACTERIAL ACTIVITY;
BACTERIAL GROWTH;
CHEMICAL REACTION;
CHO CELL;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG POTENCY;
DRUG STRUCTURE;
FEMALE;
IC 50;
MOUSE;
MYCOBACTERIUM TUBERCULOSIS;
RAT;
STRUCTURE ACTIVITY RELATION;
TOXOPLASMOSIS;
ANIMALS;
ANTI-BACTERIAL AGENTS;
ANTI-INFECTIVE AGENTS;
DRUG EVALUATION, PRECLINICAL;
ENZYME INHIBITORS;
FOLIC ACID ANTAGONISTS;
LIVER;
MYCOBACTERIUM TUBERCULOSIS;
PNEUMOCYSTIS;
PYRIMIDINES;
RATS;
TETRAHYDROFOLATE DEHYDROGENASE;
TOXOPLASMA;
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EID: 0034810332
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/S0968-0896(01)00223-1 Document Type: Article |
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Times cited : (51)
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References (31)
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