Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor

Molecular and Cellular Biology

Volumn 20, Issue 21, 2000, Pages 8254-8263

  Li, M ^a   Damania, B ^a   Alvarez, X ^a   Ogryzko, V ^a   Ozato, K ^a   Jung, J U ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HISTONE ACETYLTRANSFERASE; HISTONE H3; INTERFERON REGULATORY FACTOR 1; PROTEIN P300;

ACETYLATION; ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CELL STRAIN COS1; CHROMATIN STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; GENE REPRESSION; HUMAN HERPESVIRUS 8; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOMODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS CELL TRANSFORMATION;

3T3 CELLS; ACETYLATION; ACETYLTRANSFERASES; ANIMAL; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CELL SEPARATION; CHROMATIN; COS CELLS; CYTOKINES; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENES, REPORTER; HERPESVIRUS 8, HUMAN; HISTONES; INSECTS; MICE; MICROSCOPY, CONFOCAL; MODELS, GENETIC; MUTAGENESIS, SITE-DIRECTED; NUCLEOSOMES; OPEN READING FRAMES; PLASMIDS; PROMOTER REGIONS (GENETICS); SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0033777271     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.21.8254-8263.2000     Document Type: Article

References (52)

1. Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A
2. Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation
3. The CBP co-activator is a histone acetyltransferase
4. Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha
5. Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation
6. Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300
7. A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity
8. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
9. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300
10. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
11. Transcription factors in interferon signaling
12. A herpesvirus of rhesus monkeys related to the human Kaposi's sarcoma-associated herpesvirus
13. Association of p300 and CBP with simian virus 40 large T antigen
14. KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway
15. The cyclin encoded by Kaposi's sarcoma-associated herpesvirus stimulates cdk6 to phosphorylate the retinoblastoma protein and histone H1
16. Histone acetylation in chromatin structure and transcription
17. Transcription. A growing coactivator network
18. Three unrelated viral transforming proteins (vIRF, EBNA2, and E1A) induce the MYC oncogene through the interferon-responsive PRF element by using different transcription coadaptors
19. A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus
20. Nuclear protein CBP is a coactivator for the transcription factor CREB
21. Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor
22. Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin
23. Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP
24. The histone acetylase PCAF is a phorbol-ester-inducible coactivator of the IRF family that confers enhanced interferon responsiveness
25. Recruitment of CBP/p300 by the IFNβ enhanceosome is required for synergistic activation of transcription
26. The TAF(II)250 subunit of TFIID has histone acetyltransferase activity
27. Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV
28. Human herpesvirus 8 encodes a homolog of interleukin-6
29. Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6
30. The transcriptional coactivators p300 and CBP are histone acetyltransferases
31. Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-beta promoter
32. Differential roles of p300 and PCAF acetyltransferases in muscle differentiation
33. n-Butyrate causes histone modification in HeLa and Friend erythroleukaemia cells
34. Identification of two homologs of the Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in retroperitoneal fibromatosis of different macaque species
35. Nucleotide sequence of the Kaposi's sarcoma-associated herpesvirus (HHV8)
36. Kaposi's sarcoma-associated herpesvirus encodes a functional Bcl-2 homologue
37. Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8)
38. Sequence and genomic analysis of a rhesus macaque rhadinovirus with similarity to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8
39. Interferon-induced antiviral actions and their regulation
40. Inhibition of p53-mediated transactivation and cell cycle arrest by E1A through its p300/CBP-interacting region
41. Steroid receptor coactivator-1 is a histone acetyltransferase
42. Histone acetylation and transcriptional regulatory mechanisms
43. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
44. Transcriptional activators direct histone acetyltransferase complexes to nucleosomes
45. The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter
46. Transcriptional activation of the macrophage migration-inhibitory factor gene by the corticotropin-releasing factor is mediated by the cyclic adenosine 3',5'-monophosphate responsive element-binding protein CREB in pituitary cells
47. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-β enhancer in vivo
48. Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1
49. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
50. Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A
51. Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling
52. Human herpesvirus 8 encodes an interferon regulatory factor (IRF) homolog that represses IRF-1-mediated transcription