Molecular approaches to tuberculosis

Molecular Microbiology

Volumn 42, Issue 2, 2001, Pages 561-570

  Aínsa, José A ^a   Martín, Carlos ^a   Gicquel, Brigitte ^b  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT; ANTIGEN; ANTIGEN 85B; BCG VACCINE; CHOLESTEROL; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANTIBIOTIC RESISTANCE; BACTERIAL CELL WALL; BACTERIAL VIRULENCE; CELLULAR IMMUNITY; CONFERENCE PAPER; GENE FUNCTION; GENETICS; GENOME; HOST SUSCEPTIBILITY; HUMAN; IMMUNE RESPONSE; INTERFERON PRODUCTION; MOLECULAR DYNAMICS; MYCOBACTERIOSIS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; SURVIVAL; TUBERCULOSIS;

BCG VACCINE; CELL WALL; CHOLESTEROL; DISEASE SUSCEPTIBILITY; DRUG RESISTANCE, BACTERIAL; GENOME, BACTERIAL; HUMANS; INTERFERON TYPE II; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; TUBERCULOSIS;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM BOVIS BCG;

EID: 0034767934     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2001.02652.x     Document Type: Conference Paper

References (56)

1. Mechanisms of phagocytosis in macrophages
2. inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis
3. DNA microarrays and combinatorial chemical libraries: Tools for the drug discovery pipeline
4. Use of genomics and combinatorial chemistry in the development of new antimycobacterial drugs
5. Trafficking and release of mycobacterial lipids from infected macrophages
6. Comparative genomics of BCG vaccines by whole-genome DNA microarray
7. Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis
8. A chemical basis for selective recognition of nonpeptide antigens by human delta T cells
9. Origin and interstate spread of a New York City multidrug-resistant Mycobacterium tuberculosis clone family
10. Fitness of antibiotic-resistant microorganisms and compensatory mutations
11. ESAT-6 subunit vaccination against Mycobacterium tuberculosis
12. Comparative genomics of the mycobacteria
13. Analysis of the phthiocerol dimycocerosate locus of Mycobacterium tuberculosis
14. Identification of a virulence gene cluster of Mycobacterium tuberculosis by signature-tagged transposon mutagenesis
15. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
16. Massive gene decay in the leprosy bacillus
17. Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients
18. The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages
19. Vgamma9/Vdelta2 T lymphocytes reduce the viability of intracellular Mycobacterium tuberculosis
20. Molecular mechanics of the mycobacterial cell wall: From horizontal layers to vertical scaffolds
21. Standard short-course chemotherapy for drug-resistant tuberculosis: Treatment outcomes in 6 countries
22. Global trends in resistance to antituberculosis drugs. World Health Organization-International Union against Tuberculosis and Lung Disease Working Group on Anti-Tuberculosis Drug Resistance Surveillance
23. A coat protein on phagosomes involved in the intracellular survival of mycobacteria
24. Essential role for cholesterol in entry of mycobacteria into macrophages
25. A novel mycolic acid cyclopropane synthetase is required for coding, persistence, and virulence of Mycobacterium tuberculosis
26. Temporal and spatial arrangement of lymphocytes within lung granulomas induced by aerosol infection with Mycobacterium tuberculosis
27. Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays
28. Simultaneous identification of bacterial virulence genes by negative selection
29. Porins in the cell wall of Mycobacterium tuberculosis
30. The role of Toll-like receptors in host defense against microbial infection
31. Expression of katG in Mycobacterium tuberculosis is associated with its growth and persistence in mice and guinea pigs
32. Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase
33. Mycobacterium tuberculosis CDC1551 induces a more vigorous host response in vivo and in vitro, but is not more virulent than other clinical isolates
34. Biochemical and genetic data suggest that InhA is not the primary target for activated isoniazid in Mycobacterium tuberculosis
35. Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid
36. Efficient protection against Mycobacterium tuberculosis by vaccination with a single subdominant epitope from the ESAT-6 antigen
37. Human deficiencies in type 1 cytokine receptors reveal the essential role of type 1 cytokines in immunity to intracellular bacteria
38. An essential role for phoP in Mycobacterium tuberculosis virulence
39. Nonopsonic phagocytosis of Mycobacterium kansasii by human neutrophils depends on cholesterol and is mediated by CR3 associated with glycosylphosphatidylinositol-anchored proteins
40. Addressing multidrug-resistant tuberculosis in penitentiary hospitals and in the general population of the former Soviet Union
41. Assembly of aryl-capped siderophores by modular peptide synthetases and polyketide synthases
42. Molecular genetic analysis of nucleotide polymorphisms associated with ethambutol resistance in human isolates of Mycobacterium tuberculosis
43. Mycobacterium tuberculosis (MTB)-stimulated production of nitric oxide by human alveolar macrophages and relationship of nitric oxide production to growth inhibition of MTB
44. High rate of tuberculosis reinfection during a nosocomial outbreak of multidrug-resistant tuberculosis caused by Mycobacterium bovis strain B
45. Restricted structural gene polymorphism in the Mycobac-terium tuberculosis complex indicates evolutionarily recent global dissemination
46. Mycobacterium tuberculosis-activated dendritic cells induce protective immunity in mice
47. The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol
48. Induction of direct antimicrobial activity through mammalian toll-like receptors
49. Interaction of Mycobacterium avium-containing phagosomes with the antigen presentation pathway
50. Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages
51. Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rbeta1): Evidence for an IL-12Rbeta1-independent pathway of IL-12 responsiveness in human T cells
52. Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis
53. Latency-associated peptide of transforming growth factor beta enhances mycobacteriocidal immunity in the lung during Mycobacterium bovis BCG infection in C57BL/6 mice
54. An increase in expression of a Mycobacterium tuberculosis mycolyl transferase gene (fbpB) occurs early after infection of human monocytes
55. The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis