Decreased expression of phospholipase C-β2 isozyme in human platelets with impaired function

Blood

Volumn 88, Issue 5, 1996, Pages 1684-1691

  Lee, Sang Bong ^b   Rao, A Koneti ^b   Lee, Kweon Haeng ^b   Yang, Xu ^b   Bae, Yun Soo ^b   Rhee, Sue Goo ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE; ISOENZYME; PHOSPHOLIPASE C; PLECKSTRIN;

ADULT; ARTICLE; BLEEDING DISORDER; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL FRACTIONATION; CONTROLLED STUDY; ENZYME DEFICIENCY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; THROMBOCYTE AGGREGATION; THROMBOCYTE DYSFUNCTION; THROMBOCYTE RELEASE REACTION;

EID: 0003747219     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.5.1684.bloodjournal8851684     Document Type: Article

References (29)

1. Seiss W: Molecular mechanisms of platelet activation. Physiol Rev 69:58, 1989
2. Rink TJ, Sage SO: Calcium signaling in platelets. Ann Rev Physiol 52:431, 1990
3. Majerus PW: Inositol phosphate biochemistry. Ann Rev Biochem 61:221, 1992
4. Rhee SG, Choi KD: Regulation of inositol phospholipid-specific phospholipase C isozymes. J Biol Chem 267:12393, 1992
5. 2 hydrolysis and regulation of phospholipase C isozymes. Curr Opin Cell Biol 7:183, 1995
6. Rao AK: Congenital disorders of platelet function. Hematol Oncol Clin North Am 4:65, 1990
7. Weiss HJ: Inherited disorders of platelet secretion, in Colman RW, Hirsh J, Marder VJ, Salzman EW (eds): Hemostasis and Thrombosis: Basic Principles and Practice, (ed 4). Philadelphia, PA, Lippincott, 1994, p 673
8. Rao AK, Kowalska MA, Disa J: Impaired cytoplasmic ionized calcium mobilization in inherited platelet secretion defects. Blood 74:664, 1989
9. Rao AK, Disa J, Yang X: Concomitant defect in internal release and influx of calcium in patients with congenital platelet dysfunction and impaired agonist-induced calcium mobilization. J Lab Clin Med 121:52, 1993
10. Ryu SH, Cho KS, Lee KY, Suh PG, Rhee SG: Purification and characterization of two immunologically distinct phosphoinositide-specific phospholipase C from bovine brain. J Biol Chem 262:12511, 1987
11. Suh PG, Ryu SH, Choi WC, Lee KY, Rhee SG: Monoclonal antibodies to three phospholipase C isozymes from bovine brain. J Biol Chem 263:14497, 1988
12. q-independent activation of phospholipase C-β2. J Biol Chem 267:16048, 1992
13. q-dependent activation of phospholipase C-β3. J Biol Chem 268:6654, 1993
14. Lee CW, Park DJ, Lee KH, Kim CG, Rhee SG: Purification, molecular cloning, and sequencing of phospholipase C-β4. J Biol Chem 268:21318, 1993
15. Liao F, Shin HS, Rhee SG: Cross-linking of Fcγ RIIIA on natural killer cells results in tyrosine phosphorylation of PLC-γ1 and PLC-γ2. J Immunol 150:2668, 1993
16. Lee SB, Rhee SG: Molecular cloning, splice variants, expression, and purification of phospholipase C-δ4. J Biol Chem 271:25, 1996
17. Lee KY, Ryu SH, Suh PG, Choi WC, Rhee SG: Phospholipase C associated with particulate fractions of bovine brain. Proc Natl Acad Sci USA 84:5540, 1987
18. Banno Y, Nakashima S, Kumata T, Ebisawa K, Nonomura Y, Nozawa Y: Effects of gelsolin on human platelet cytosolic phosphoinositide-phospholipase C isozymes. J Biol Chem 267:6488, 1992
19. Banno Y, Nakashima S, Hachiya T, Nozawa Y: Endogenous cleavage of phospholipase C by agonist-induced activation in human platelets. J Biol Chem 270:4318, 1995
20. q. J Biol Chem 269:25335, 1994
21. Tate BF, Rittenhouse SE: Thrombin activation of human platelets causes tyrosine phosphorylation of PLC-γ2. Biochim Biophys Acta 1178:281, 1993
22. Blake RA, Schieven GL, Watson SP: Collagen stimulates tyrosine phosphorylation of phospholipase C-gamma 2 but not phospholipase C-gamma 1 in human platelets. FEBS Lett 353:212, 1994
23. Daniel JM, Dangelmaier C, Smith JB: Evidence for a role for tyrosine phosphorylation of phospholipase C gamma 2 in collagen-induced platelet cytosolic calcium mobilization. Biochem J 302:617, 1994
24. Guinebault C, Payrastre B, Sultan C, Mauco G, Breton M, Levy-Toledano S, Plantavid M, Chap H: Tyrosine kinases and phosphoinositide metabolism in thrombin-stimulated platelets. Biochem J 292:851, 1993
25. Fee JA, Monsey JD, Handler RJ, Leonis MA, Mullaney SR, Hope HMR, Silbert DF: A Chinese hamster fibroblst mutant defective in thrombin-induced signaling has a low level of phospholipase C-β1. J Biol Chem 269:21699, 1994
26. Yang X, Sun L, Ghosh S, Rao AK: Human platelet signaling defect characterized by impaired production of inositol-1,4,5-triphosphate and phosphatic acid and diminished Pleckstrin phosphorylation: Evidence for defective phopholipase C activation. Blood 88:1676, 1996.
27. Shenker A, Goldsmith P, Unson CG, Spiegel AM: The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. J Biol Chem 266:9309, 1991
28. Baffy G, Yang L, Raj S, Manning DR, Williamson JR: G protein coupling to the thrombin receptor in Chinese hamster lung fibroblasts. J Biol Chem 269: 8483, 1994
29. v-src monoclonal antibody inhibits activation of phospholipase C in platelets. J Biol Chem 269:9123, 1994