Blocking platelet aggregation inhibits thromboxane A2 formation by low dose agonists but does not inhibit phosphorylation and activation of cytosolic phospholipase A2

Thrombosis Research

Volumn 88, Issue 2, 1997, Pages 109-125

  Carroll, Roger C ^a   Wang, Xiao Fen ^a   Lanza, Francois ^b   Steiner, Beat ^c   Kouns, William C ^c  

^a UNIVERSITY OF TENNESSEE GRADUATE SCHOOL OF MEDICINE   (United States)

^b ETABLISSEMENT FRANÇAIS DU SANG   (France)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Fibrinogen receptor antagonists; Human platelet aggregation; Phospholipid metabolites

Indexed keywords

COLLAGEN; LAMIFIBAN; PHOSPHOLIPASE A2; THROMBOXANE A2;

ARTICLE; ELECTROIMMUNOASSAY; ENZYME ACTIVATION; ENZYME IMMUNOASSAY; HUMAN; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SEROTONIN RELEASE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOSIS;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ACETATES; ADENOSINE DIPHOSPHATE; BLOOD PLATELETS; CYTOPLASMIC GRANULES; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HUMANS; LYSOPHOSPHOLIPIDS; PEPTIDE FRAGMENTS; PHOSPHORYLASE A; PHOSPHORYLATION; PLASMA; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; SEROTONIN; THROMBASTHENIA; THROMBOXANE A2; TYROSINE; VASOCONSTRICTOR AGENTS;

EID: 0030724469     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(97)00223-5     Document Type: Article

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