A (1→3)-β-D-linked heptasaccharide is the unit ligand for glucan pattern recognition receptors on human monocytes

Microbes and Infection

Volumn 3, Issue 10, 2001, Pages 789-797

  Lowe, Elizabeth ^a   Rice, Peter ^a   Ha, Tuanzhu ^a   Li, Chuanfu ^a   Kelley, Jim ^a   Ensley, Harry ^a,b   Lopez Perez, Jose ^b   Kalbfleisch, John ^a   Lowman, Douglas ^a,c   Margl, Peter ^a,c   Browder, William ^a   Williams, David ^a  

^a East Tennessee State University   (United States)

^b Tulane University   (United States)

^c EASTMAN CHEMICAL COMPANY   (United States)

Author keywords

Glucan; Heptasaccharide; Macrophage; Monocyte; NF B; Receptors; Sepsis

Indexed keywords

CARBOHYDRATE DERIVATIVE; GLUCAN; HEPTASACCHARIDE; HEPTOSE; HEXOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LAMINARAN; MEMBRANE RECEPTOR; PENTOSE; POLYMER; UNCLASSIFIED DRUG; BETA GLUCAN RECEPTOR; BETA-GLUCAN RECEPTOR; IMMUNOGLOBULIN RECEPTOR; LIGAND; POLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CELL MEMBRANE; CELL STRAIN U937; CONTROLLED STUDY; HUMAN; HUMAN CELL; INHIBITION KINETICS; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PATTERN RECOGNITION; PRIORITY JOURNAL; PROTECTION; RECEPTOR BINDING; SEPSIS; SIGNAL TRANSDUCTION; STIMULATION; SURFACE PROPERTY; SURVIVAL; ANIMAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; HAIRLESS MOUSE; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PROTEIN BINDING;

MURINAE;

ANIMALS; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCANS; HUMANS; LIGANDS; MALE; MICE; MICE, INBRED HRS; MICE, INBRED ICR; MONOCYTES; NF-KAPPA B; POLYSACCHARIDES; PROTEIN BINDING; RECEPTORS, IMMUNOLOGIC; SEPSIS; U937 CELLS;

EID: 0034741094     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(01)01436-8     Document Type: Article

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