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Volumn 65, Issue 13, 2000, Pages 4088-4100

Selective metal cation activation of a DNA alkylating agent: Synthesis and evaluation of methyl 1,2,9,9a-tetrahydrocyclopropa[c]pyrido[3,2-e]indol-4-one-7-carboxylate (CPyI)

(2) Boger, D L a Boyce, C W a

a SCRIPPS RESEARCH INSTITUTE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; ANTINEOPLASTIC ANTIBIOTIC; COPPER ION; DUOCARMYCIN A; DUOCARMYCIN SA; MAGNESIUM ION; MANGANESE; METAL COMPLEX; METHYL 1,2,9,9A TETRAHYDROCYCLOPROPA[C]PYRIDO[3,2 E]INDOL 4 ONE 7 CARBOXYLIC ACID; NICKEL; RACHELMYCIN; UNCLASSIFIED DRUG; ZINC ION;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CATALYSIS; CHEMICAL REACTION; CYCLIZATION; DNA ALKYLATION; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS;

ALKYLATING AGENTS; ANTIBIOTICS, ANTINEOPLASTIC; BASE SEQUENCE; CATALYSIS; CATIONS, DIVALENT; DNA; DNA, VIRAL; INDICATORS AND REAGENTS; INDOLES; METALS; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PYRROLES; QUINOLONES; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM;

EID: 0034733099 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo000177b Document Type: Article

Times cited : (50)

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