Catalytic mechanism of enterococcal kanamycin kinase (APH(3')-IIIa): Viscosity, thio, and solvent isotope effects support a Theorell-Chance mechanism

Biochemistry

Volumn 35, Issue 26, 1996, Pages 8680-8685

  McKay, Geoffrey A ^a   Wright, Gerard D ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; BACTERIAL ENZYME; GLYCEROL; ISOTOPE; KANAMYCIN A; MACROGOL 8000; NEOMYCIN; SOLVENT; SUCROSE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL INFECTION; CATALYSIS; ENTEROCOCCUS; ENZYME ASSAY; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; HOSPITAL INFECTION; MICHAELIS MENTEN KINETICS; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS; VISCOSITY;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; CATALYSIS; DRUG RESISTANCE, MICROBIAL; ENTEROCOCCUS; ISOTOPES; KANAMYCIN KINASE; KINETICS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SOLVENTS; SULFHYDRYL COMPOUNDS; THERMODYNAMICS; VISCOSITY;

EID: 0029941909     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9603884     Document Type: Article

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