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Volumn 107, Issue 2, 2000, Pages 205-215

The role of costimulation in autoimmune demyelination

Author keywords

Autoimmune demyelination; Costimulation; Experimental allergic encephalomyelitis; Immunologically based therapy; Multiple sclerosis

Indexed keywords

ANTIBODY; AUTOANTIGEN; CD28 ANTIGEN; CYTOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; ENCEPHALITOGENIC PROTEIN; GAMMA INTERFERON; GLYCOPROTEIN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; L SELECTIN; LYMPHOKINE; LYMPHOTOXIN; MYELIN; PERTUSSIS TOXIN; T LYMPHOCYTE RECEPTOR;

EID: 0034710342     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(00)00230-7     Document Type: Conference Paper
Times cited : (48)

References (106)
  • 1
    • 0025138302 scopus 로고
    • T cells responsive to myelin basic protein in patients with multiple sclerosis
    • Allegretta M., Nicklas J.A., Sriram S., Albertini R.J. T cells responsive to myelin basic protein in patients with multiple sclerosis. Science. 247:1990;718-721.
    • (1990) Science , vol.247 , pp. 718-721
    • Allegretta, M.1    Nicklas, J.A.2    Sriram, S.3    Albertini, R.J.4
  • 3
    • 0024368359 scopus 로고
    • Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype
    • Ando D.G., Clayton J., Kono D., Urban J.L., Sercarz E.E. Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell. Immunol. 124:1989;132-143.
    • (1989) Cell. Immunol. , vol.124 , pp. 132-143
    • Ando, D.G.1    Clayton, J.2    Kono, D.3    Urban, J.L.4    Sercarz, E.E.5
  • 4
    • 0020801186 scopus 로고
    • Relevance of experimental allergic encephalomyelitis to multiple sclerosis
    • Arnason B.G. Relevance of experimental allergic encephalomyelitis to multiple sclerosis. Neurol. Clin. 1:1983;765-782.
    • (1983) Neurol. Clin. , vol.1 , pp. 765-782
    • Arnason, B.G.1
  • 7
    • 0027182225 scopus 로고
    • Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle
    • Boehme S.A., Lenardo M.J. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur. J. Immunol. 23:1993;1552-1560.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1552-1560
    • Boehme, S.A.1    Lenardo, M.J.2
  • 8
    • 0026541544 scopus 로고
    • The two-signal model of lymphocyte activation twenty-one years later
    • Bretscher P. The two-signal model of lymphocyte activation twenty-one years later. Immunol. Today. 13:1992;74-76.
    • (1992) Immunol. Today , vol.13 , pp. 74-76
    • Bretscher, P.1
  • 9
    • 0015786747 scopus 로고
    • Myelin basic protein administration in multiple sclerosis
    • Campbell B., Vogel P.J., Fisher E., Lorenz R. Myelin basic protein administration in multiple sclerosis. Arch. Neurol. 29:1973;10-15.
    • (1973) Arch. Neurol. , vol.29 , pp. 10-15
    • Campbell, B.1    Vogel, P.J.2    Fisher, E.3    Lorenz, R.4
  • 10
    • 0027513268 scopus 로고
    • Apoptosis
    • Cohen J.J. Apoptosis. Immunol. Today. 14:1993;126-130.
    • (1993) Immunol. Today , vol.14 , pp. 126-130
    • Cohen, J.J.1
  • 11
    • 0028906889 scopus 로고
    • Patterns of cytokine secretion by autoreactive proteolipid protein-specific T cell clones during the course of multiple sclerosis
    • Correale J., Gilmore W., McMillan M., Li S., McCarthy K., Le T., Weiner L.P. Patterns of cytokine secretion by autoreactive proteolipid protein-specific T cell clones during the course of multiple sclerosis. J. Immunol. 154:1995;2959-2968.
    • (1995) J. Immunol. , vol.154 , pp. 2959-2968
    • Correale, J.1    Gilmore, W.2    McMillan, M.3    Li, S.4    McCarthy, K.5    Le, T.6    Weiner, L.P.7
  • 13
    • 0028316562 scopus 로고
    • Naive versus memory CD4 T cell response to antigen: Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells
    • Croft M., Bradley L.M., Swain S.L. Naive versus memory CD4 T cell response to antigen: Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells. J. Immunol. 152:1994;2675-2685.
    • (1994) J. Immunol. , vol.152 , pp. 2675-2685
    • Croft, M.1    Bradley, L.M.2    Swain, S.L.3
  • 14
    • 0027403782 scopus 로고
    • Development of reactivity to new myelin antigens during chronic relapsing autoimmune demyelination
    • Cross A.H., Tuohy V.K., Raine C.S. Development of reactivity to new myelin antigens during chronic relapsing autoimmune demyelination. Cell. Immunol. 146:1993;261-269.
    • (1993) Cell. Immunol. , vol.146 , pp. 261-269
    • Cross, A.H.1    Tuohy, V.K.2    Raine, C.S.3
  • 15
    • 0032842355 scopus 로고    scopus 로고
    • T cells are the main cell type expressing B7-1 and B7-2 in the central nervous system during acute, relapsing, and chronic experimental autoimmune encephalomyelitis
    • Cross A.H., Lyons J.A., San M., Keeling R.M., Ku G., Racke M.K. T cells are the main cell type expressing B7-1 and B7-2 in the central nervous system during acute, relapsing, and chronic experimental autoimmune encephalomyelitis. Eur. J. Immunol. 29:1999;1753-1761.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 1753-1761
    • Cross, A.H.1    Lyons, J.A.2    San, M.3    Keeling, R.M.4    Ku, G.5    Racke, M.K.6
  • 16
    • 0019805542 scopus 로고
    • Monoclonal antibody analysis of human T lymphocyte subpopulations exhibiting autologous mixed lymphocyte reaction
    • Damle N.K., Hansen J.A., Good R.A., Gupta S. Monoclonal antibody analysis of human T lymphocyte subpopulations exhibiting autologous mixed lymphocyte reaction. Proc. Natl. Acad. Sci. USA. 78:1981;5096-5098.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 5096-5098
    • Damle, N.K.1    Hansen, J.A.2    Good, R.A.3    Gupta, S.4
  • 17
    • 0026529976 scopus 로고
    • Differential costimulatory effects of adhesion molecules B7, ICAM-1, LFA-3, and VCAM-1 on resting and antigen-primed CD4+ T lymphocytes
    • Damle N.K., Klussman K., Linsley P.S., Aruffo A. Differential costimulatory effects of adhesion molecules B7, ICAM-1, LFA-3, and VCAM-1 on resting and antigen-primed CD4+ T lymphocytes. J. Immunol. 148:1992;1985-1992.
    • (1992) J. Immunol. , vol.148 , pp. 1985-1992
    • Damle, N.K.1    Klussman, K.2    Linsley, P.S.3    Aruffo, A.4
  • 18
    • 0025950146 scopus 로고
    • Selective induction of B7/BB-1 on interferon-g stimulated monocytes: A potential mechanism for amplification of T cell activation
    • Freedman A.S., Freeman G.J., Rhynhart K., Nadler L.M. Selective induction of B7/BB-1 on interferon-g stimulated monocytes: A potential mechanism for amplification of T cell activation. Cell. Immunol. 137:1991;429-437.
    • (1991) Cell. Immunol. , vol.137 , pp. 429-437
    • Freedman, A.S.1    Freeman, G.J.2    Rhynhart, K.3    Nadler, L.M.4
  • 22
    • 0024840204 scopus 로고
    • Encephalitogenic epitopes of myelin basic protein
    • E.E. Sercarz. Basel: Karger
    • Fritz R.B., McFarlin D.E. Encephalitogenic epitopes of myelin basic protein. Sercarz E.E. Antigenic Determinants and Immune Response. 1989;101-125 Karger, Basel.
    • (1989) Antigenic Determinants and Immune Response , pp. 101-125
    • Fritz, R.B.1    McFarlin, D.E.2
  • 23
    • 0030589288 scopus 로고    scopus 로고
    • Thymic expression of myelin basic protein (MBP): Activation of MBP-specific T cells by thymic cells in the absence of exogenous MBP
    • Fritz R.B., Zhao M.-L. Thymic expression of myelin basic protein (MBP): activation of MBP-specific T cells by thymic cells in the absence of exogenous MBP. J. Immunol. 157:1996;5249-5253.
    • (1996) J. Immunol. , vol.157 , pp. 5249-5253
    • Fritz, R.B.1    Zhao, M.-L.2
  • 24
    • 0021924965 scopus 로고
    • Major histocompatibility complex-linked control of the murine immune response to myelin basic protein
    • Fritz R.B., Skeen M.J., Jen-Chou C.H., Garcia M., Egorov I.K. Major histocompatibility complex-linked control of the murine immune response to myelin basic protein. J. Immunol. 134:1985;2328-2332.
    • (1985) J. Immunol. , vol.134 , pp. 2328-2332
    • Fritz, R.B.1    Skeen, M.J.2    Jen-Chou, C.H.3    Garcia, M.4    Egorov, I.K.5
  • 25
    • 0027056539 scopus 로고
    • Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy
    • Gaur A., Wiers B., Liu A., Rothbard J., Fathman G.C. Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. Science. 258:1993;1491-1493.
    • (1993) Science , vol.258 , pp. 1491-1493
    • Gaur, A.1    Wiers, B.2    Liu, A.3    Rothbard, J.4    Fathman, G.C.5
  • 27
    • 0027284230 scopus 로고
    • Human T cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation
    • Gimmi C.D., Freeman G.J., Gribben J.G., Gray G., Nadler L.M. Human T cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc. Natl. Acad. Sci. USA. 90:1993;6586-6590.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6586-6590
    • Gimmi, C.D.1    Freeman, G.J.2    Gribben, J.G.3    Gray, G.4    Nadler, L.M.5
  • 28
    • 0017686130 scopus 로고
    • Failure of basic protein therapy for multiple sclerosis
    • Gonsette R.E., Delmotte P., Demonty L. Failure of basic protein therapy for multiple sclerosis. J. Neurol. 216:1977;27-31.
    • (1977) J. Neurol. , vol.216 , pp. 27-31
    • Gonsette, R.E.1    Delmotte, P.2    Demonty, L.3
  • 29
    • 0027468174 scopus 로고
    • Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity
    • Goverman J., Woods A., Larson L., Weiner L.P., Hood L., Zaller D.M. Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell. 72:1993;551-560.
    • (1993) Cell , vol.72 , pp. 551-560
    • Goverman, J.1    Woods, A.2    Larson, L.3    Weiner, L.P.4    Hood, L.5    Zaller, D.M.6
  • 33
    • 0028337459 scopus 로고
    • Comparative analysis of B7-1 and B7-2 costimulatory ligands: Expression and function
    • Hathcock K.S., Laszlo G., Pucillo C., Linsley P., Hodes R.J. Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. J. Exp. Med. 180:1994;631-640.
    • (1994) J. Exp. Med. , vol.180 , pp. 631-640
    • Hathcock, K.S.1    Laszlo, G.2    Pucillo, C.3    Linsley, P.4    Hodes, R.J.5
  • 34
    • 0027418515 scopus 로고
    • Interferon beta-1b is effective in relapsing-remitting multiple sclerosis I: Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial
    • Interferon beta-1b is effective in relapsing-remitting multiple sclerosis I: clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology. 43:1995;655-661.
    • (1995) Neurology , vol.43 , pp. 655-661
  • 35
    • 0008678962 scopus 로고    scopus 로고
    • Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis
    • Jacobs L.D., Cookfair D.L., Rudick R.A. Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. Ann. Neurol. 39:1996;285-294.
    • (1996) Ann. Neurol. , vol.39 , pp. 285-294
    • Jacobs, L.D.1    Cookfair, D.L.2    Rudick, R.A.3
  • 36
    • 0027285630 scopus 로고
    • Molecules involved in T-cell costimulation
    • Jenkins M.K., Johnson J.G. Molecules involved in T-cell costimulation. Curr. Opin. Immunol. 5:1993;351-367.
    • (1993) Curr. Opin. Immunol. , vol.5 , pp. 351-367
    • Jenkins, M.K.1    Johnson, J.G.2
  • 37
    • 0029082566 scopus 로고
    • Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: Results of a phase III multicenter, double-blind, placebo-controlled trial
    • Johnson K.P., Brooks B.R., Cohen J.A. Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind, placebo-controlled trial. Neurology. 45:1995;1268-1276.
    • (1995) Neurology , vol.45 , pp. 1268-1276
    • Johnson, K.P.1    Brooks, B.R.2    Cohen, J.A.3
  • 39
    • 0026696776 scopus 로고
    • CD4+ suppressor cells of autoimmune encephalomyelitis respond to T cell receptor-associated determinants on effector cells by interleukin-4 secretion
    • Karpus W.J., Gould K.E., Swanborg R.H. CD4+ suppressor cells of autoimmune encephalomyelitis respond to T cell receptor-associated determinants on effector cells by interleukin-4 secretion. Eur. J. Immunol. 22:1992;1757-1763.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 1757-1763
    • Karpus, W.J.1    Gould, K.E.2    Swanborg, R.H.3
  • 40
    • 0343604701 scopus 로고
    • Programmed cell death and extrathymic reduction of Vb8+ CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B
    • Kawabe Y., Ochi A. Programmed cell death and extrathymic reduction of Vb8+ CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B. Nature. 349:1981;295-298.
    • (1981) Nature , vol.349 , pp. 295-298
    • Kawabe, Y.1    Ochi, A.2
  • 41
    • 0025174370 scopus 로고
    • Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides
    • Kennedy M.K., Tan L.-J., Dal Canto M.C., Tuohy V.K., Lu Z., Trotter J.L., Miller S.D. Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides. J. Immunol. 144:1990;909-915.
    • (1990) J. Immunol. , vol.144 , pp. 909-915
    • Kennedy, M.K.1    Tan, L.-J.2    Dal Canto, M.C.3    Tuohy, V.K.4    Lu, Z.5    Trotter, J.L.6    Miller, S.D.7
  • 42
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
    • Kennedy M.K., Torrance D.S., Picha K.S., Mohler K.M. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J. Immunol. 149:1992;2496-2505.
    • (1992) J. Immunol. , vol.149 , pp. 2496-2505
    • Kennedy, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 43
    • 0002204915 scopus 로고
    • Definition and incidence of apoptosis: An historical perspective
    • D. Tomei, & F. Cope. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
    • Kerr J.F.R., Harmon B.V. Definition and incidence of apoptosis: an historical perspective. Tomei D., Cope F. Apoptosis: The Molecular Basis of Cell Death. 1991;5-29 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
    • (1991) Apoptosis: The Molecular Basis of Cell Death , pp. 5-29
    • Kerr, J.F.R.1    Harmon, B.V.2
  • 44
    • 0028829010 scopus 로고
    • Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells
    • Khoruts A., Miller S.D., Jenkins M.K. Neuroantigen-specific Th2 cells are inefficient suppressors of experimental autoimmune encephalomyelitis induced by effector Th1 cells. J. Immunol. 155:1995;5011-5017.
    • (1995) J. Immunol. , vol.155 , pp. 5011-5017
    • Khoruts, A.1    Miller, S.D.2    Jenkins, M.K.3
  • 46
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
    • Kuchroo V.K., Das M.B., Brown J.A., Ranger A.M., Zamvil S.S., Sobel R.A., Weiner H.L., Nabavi N., Glimcher L.H. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell. 80:1995;707-718.
    • (1995) Cell , vol.80 , pp. 707-718
    • Kuchroo, V.K.1    Das, M.B.2    Brown, J.A.3    Ranger, A.M.4    Zamvil, S.S.5    Sobel, R.A.6    Weiner, H.L.7    Nabavi, N.8    Glimcher, L.H.9
  • 48
    • 0026664422 scopus 로고
    • Spreading of T cell autoimmunity to cryptic determinants of an autoantigen
    • Lehmann P.V., Forsthuber T., Miller A., Sercarz E.E. Spreading of T cell autoimmunity to cryptic determinants of an autoantigen. Nature. 358:1992;155-157.
    • (1992) Nature , vol.358 , pp. 155-157
    • Lehmann, P.V.1    Forsthuber, T.2    Miller, A.3    Sercarz, E.E.4
  • 49
    • 0026017971 scopus 로고
    • Interleukin-2 programs mouse ab T lymphocytes for apoptosis
    • Lenardo M.J. Interleukin-2 programs mouse ab T lymphocytes for apoptosis. Nature. 353:1991;858-861.
    • (1991) Nature , vol.353 , pp. 858-861
    • Lenardo, M.J.1
  • 51
    • 0028900297 scopus 로고
    • Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the non-obese diabetic mouse
    • Lenschow D.J., Ho S.C., Sattar H., Rhee L., Gray G., Nabavi N., Herold K.C., Bluestone J.A. Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the non-obese diabetic mouse. J. Exp. Med. 181:1995;1145-1155.
    • (1995) J. Exp. Med. , vol.181 , pp. 1145-1155
    • Lenschow, D.J.1    Ho, S.C.2    Sattar, H.3    Rhee, L.4    Gray, G.5    Nabavi, N.6    Herold, K.C.7    Bluestone, J.A.8
  • 53
    • 0027451441 scopus 로고
    • Long-term acceptance of major histocompatibility mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion
    • Lin H., Bolling S.F., Linsley P.S., Wei R.Q., Gordon D., Thompson C.B., Turka L.A. Long-term acceptance of major histocompatibility mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion. J. Exp. Med. 178:1993;1801-1806.
    • (1993) J. Exp. Med. , vol.178 , pp. 1801-1806
    • Lin, H.1    Bolling, S.F.2    Linsley, P.S.3    Wei, R.Q.4    Gordon, D.5    Thompson, C.B.6    Turka, L.A.7
  • 54
    • 0023931606 scopus 로고
    • Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein
    • Linington C., Bradl M., Lassman H., Brunner C., Vass K. Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein. Am. J. Pathol. 130:1988;443-454.
    • (1988) Am. J. Pathol. , vol.130 , pp. 443-454
    • Linington, C.1    Bradl, M.2    Lassman, H.3    Brunner, C.4    Vass, K.5
  • 56
    • 0028675006 scopus 로고
    • Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
    • Linsley P.S., Greene J.I., Brady W., Bajorath J., Ledbetter J.A., Peach R. Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors. Immunity. 1:1994;793-801.
    • (1994) Immunity , vol.1 , pp. 793-801
    • Linsley, P.S.1    Greene, J.I.2    Brady, W.3    Bajorath, J.4    Ledbetter, J.A.5    Peach, R.6
  • 57
    • 0026559329 scopus 로고
    • Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells
    • Liu Y., Janeway C.A. Jr. Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells. Proc. Natl. Acad. Sci. USA. 89:1992;3845-3849.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 3845-3849
    • Liu, Y.1    Janeway C.A., Jr.2
  • 58
    • 0030803681 scopus 로고    scopus 로고
    • Longitudinal study of myelin basic protein-specific T cell receptors during the course of multiple sclerosis
    • Lovett-Racke A.E., Martin R., McFarland H.F., Racke M.K., Utz U. Longitudinal study of myelin basic protein-specific T cell receptors during the course of multiple sclerosis. J. Neuroimmunol. 78:1997;162-171.
    • (1997) J. Neuroimmunol. , vol.78 , pp. 162-171
    • Lovett-Racke, A.E.1    Martin, R.2    McFarland, H.F.3    Racke, M.K.4    Utz, U.5
  • 59
    • 0032519421 scopus 로고    scopus 로고
    • Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients: A marker of activated/memory T cells
    • Lovett-Racke A.E., Trotter J.L., Lauber J., Perrin P.J., June C.H., Racke M.K. Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients: A marker of activated/memory T cells. J. Clin. Invest. 101:1998;725-730.
    • (1998) J. Clin. Invest. , vol.101 , pp. 725-730
    • Lovett-Racke, A.E.1    Trotter, J.L.2    Lauber, J.3    Perrin, P.J.4    June, C.H.5    Racke, M.K.6
  • 61
    • 0027486499 scopus 로고
    • Myelin basic protein-specific T-cell responses in identical twins discordant or concordant for multiple sclerosis
    • Martin R., Voskuhl R., Flerlage M., McFarlin D.E., McFarland H.F. Myelin basic protein-specific T-cell responses in identical twins discordant or concordant for multiple sclerosis. Ann. Neurol. 34:1993;524-535.
    • (1993) Ann. Neurol. , vol.34 , pp. 524-535
    • Martin, R.1    Voskuhl, R.2    Flerlage, M.3    McFarlin, D.E.4    McFarland, H.F.5
  • 62
    • 0002085474 scopus 로고
    • The epidemiology of multiple sclerosis
    • W.B. Matthews. New York, NY: Churchill Livingstone. Ch. 1
    • Martyn C.N. The epidemiology of multiple sclerosis. Matthews W.B. McAlpine's Multiple Sclerosis. 2nd Edition :1991;Churchill Livingstone, New York, NY. Ch. 1.
    • (1991) McAlpine's Multiple Sclerosis 2nd Edition
    • Martyn, C.N.1
  • 63
    • 0025075249 scopus 로고
    • Alterations in T cell antigen specificity and class II restriction during the course of chronic relapsing experimental allergic encephalomyelitis
    • McCarron R.M., Fallis R.J., McFarlin D.E. Alterations in T cell antigen specificity and class II restriction during the course of chronic relapsing experimental allergic encephalomyelitis. J. Neuroimmunol. 29:1990;73-79.
    • (1990) J. Neuroimmunol. , vol.29 , pp. 73-79
    • McCarron, R.M.1    Fallis, R.J.2    McFarlin, D.E.3
  • 64
    • 0029000750 scopus 로고
    • Functional evidence for epitope spreading in the relapsing pathology of EAE in the SJL/J Mouse
    • McRae B.L., Vanderlugt C.L., Dal Canto M.C., Miller S.D. Functional evidence for epitope spreading in the relapsing pathology of EAE in the SJL/J Mouse. J. Exp. Med. 182:1995;75-85.
    • (1995) J. Exp. Med. , vol.182 , pp. 75-85
    • McRae, B.L.1    Vanderlugt, C.L.2    Dal Canto, M.C.3    Miller, S.D.4
  • 65
    • 0028067008 scopus 로고
    • The immunopathogenesis and regulation of T-cell mediated demyelinating diseases
    • Miller S.D., Karpus W.J. The immunopathogenesis and regulation of T-cell mediated demyelinating diseases. Immunol. Today. 15:1994;356-361.
    • (1994) Immunol. Today , vol.15 , pp. 356-361
    • Miller, S.D.1    Karpus, W.J.2
  • 67
    • 0027158798 scopus 로고
    • Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells
    • Moskophidis D., Lechner F., Pircher H., Zinkernagel R.M. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature. 362:1993;758-761.
    • (1993) Nature , vol.362 , pp. 758-761
    • Moskophidis, D.1    Lechner, F.2    Pircher, H.3    Zinkernagel, R.M.4
  • 68
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann T.R., Coffman R.L. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:1989;145-173.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 70
    • 0028980902 scopus 로고
    • Fas and Fas ligand: Lpr and gld mutations
    • Nagata S., Suda T. Fas and Fas ligand: lpr and gld mutations. Immunol. Today. 16:1995;39-43.
    • (1995) Immunol. Today , vol.16 , pp. 39-43
    • Nagata, S.1    Suda, T.2
  • 72
    • 0026661264 scopus 로고
    • Apoptosis of ab T lymphocytes in the nervous system in experimental autoimmune encephalomyelitis: Its possible implications for recovery and acquired tolerance
    • Pender M.P., McCombe P.A., Yoong G., Nguyen K.B. Apoptosis of ab T lymphocytes in the nervous system in experimental autoimmune encephalomyelitis: Its possible implications for recovery and acquired tolerance. J. Autoimmunity. 5:1992;401-410.
    • (1992) J. Autoimmunity , vol.5 , pp. 401-410
    • Pender, M.P.1    McCombe, P.A.2    Yoong, G.3    Nguyen, K.B.4
  • 73
    • 0029619838 scopus 로고
    • B7-mediated costimulation can either provoke or prevent clinical manifestations of experimental allergic encephalomyelitis
    • Perrin P.J., Scott D., June C.H., Racke M.K. B7-mediated costimulation can either provoke or prevent clinical manifestations of experimental allergic encephalomyelitis. Immunol. Res. 14:1995;189-199.
    • (1995) Immunol. Res. , vol.14 , pp. 189-199
    • Perrin, P.J.1    Scott, D.2    June, C.H.3    Racke, M.K.4
  • 75
    • 0029921933 scopus 로고    scopus 로고
    • Opposing effects of CTLA4-Ig and anti-CD80 (B7-1) plus anti-CD86 (B7-2) on experimental allergic encephalomyelitis
    • Perrin P.J., Scott D., Davis T.A., Gray G.S., Doggett M.J., Abe R., June C.H., Racke M.K. Opposing effects of CTLA4-Ig and anti-CD80 (B7-1) plus anti-CD86 (B7-2) on experimental allergic encephalomyelitis. J. Neuroimmunol. 65:1996;31-39.
    • (1996) J. Neuroimmunol. , vol.65 , pp. 31-39
    • Perrin, P.J.1    Scott, D.2    Davis, T.A.3    Gray, G.S.4    Doggett, M.J.5    Abe, R.6    June, C.H.7    Racke, M.K.8
  • 76
    • 0030586626 scopus 로고    scopus 로고
    • CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis
    • Perrin P.J., Maldonado J.H., Davis T.A., June C.H., Racke M.K. CTLA-4 blockade enhances clinical disease and cytokine production during experimental allergic encephalomyelitis. J. Immunol. 157:1996;1333-1336.
    • (1996) J. Immunol. , vol.157 , pp. 1333-1336
    • Perrin, P.J.1    Maldonado, J.H.2    Davis, T.A.3    June, C.H.4    Racke, M.K.5
  • 77
    • 0033179230 scopus 로고    scopus 로고
    • Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis
    • Perrin P.J., June C.H., Maldonaldo J.H., Ratts R., Racke M.K. Blockade of CD28 during in vitro activation of encephalitogenic T cells or after disease onset ameliorates experimental autoimmune encephalomyelitis. J. Immunol. 163:1999;1704-1710.
    • (1999) J. Immunol. , vol.163 , pp. 1704-1710
    • Perrin, P.J.1    June, C.H.2    Maldonaldo, J.H.3    Ratts, R.4    Racke, M.K.5
  • 78
    • 0033109039 scopus 로고    scopus 로고
    • Experimental autoimmune meningitis: A novel neurological disease in CD28-deficient mice demonstrate the importance of CD28 in T cell differentiation
    • Perrin P.J., Lavi E., Zekavat S.A., Rumbley C.A., Phillips S.M. Experimental autoimmune meningitis: a novel neurological disease in CD28-deficient mice demonstrate the importance of CD28 in T cell differentiation. Clin. Immunol. 91:1999;41-49.
    • (1999) Clin. Immunol. , vol.91 , pp. 41-49
    • Perrin, P.J.1    Lavi, E.2    Zekavat, S.A.3    Rumbley, C.A.4    Phillips, S.M.5
  • 79
    • 0025188659 scopus 로고
    • Myelin basic protein-specific T lymphocyte lines from MS patients and healthy individuals
    • Pette M., Fujita K., Kitze B., Whitaker J.N., Albert E., Kappos L., Wekerle H. Myelin basic protein-specific T lymphocyte lines from MS patients and healthy individuals. Neurology. 40:1990;1770-1776.
    • (1990) Neurology , vol.40 , pp. 1770-1776
    • Pette, M.1    Fujita, K.2    Kitze, B.3    Whitaker, J.N.4    Albert, E.5    Kappos, L.6    Wekerle, H.7
  • 81
    • 0028785417 scopus 로고
    • Distinct roles for B7-1 (CD80) and B7-2 (CD86) in the initiation of experimental allergic encephalomyelitis
    • Racke M.K., Scott D.E., Quigley L., Gray G.S., Abe R., June C.H., Perrin P.J. Distinct roles for B7-1 (CD80) and B7-2 (CD86) in the initiation of experimental allergic encephalomyelitis. J. Clin. Invest. 96:1995;2195-2203.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2195-2203
    • Racke, M.K.1    Scott, D.E.2    Quigley, L.3    Gray, G.S.4    Abe, R.5    June, C.H.6    Perrin, P.J.7
  • 83
    • 0021592979 scopus 로고
    • Biology of disease. Analysis of autoimmune demyelination: Its impact upon multiple sclerosis
    • Raine C.S. Biology of disease. Analysis of autoimmune demyelination: its impact upon multiple sclerosis. Lab. Invest. 50:1984;608-635.
    • (1984) Lab. Invest. , vol.50 , pp. 608-635
    • Raine, C.S.1
  • 84
    • 0018091716 scopus 로고
    • Suppression of chronic allergic encephalomyelitis: Relevance to multiple sclerosis
    • Raine C.S., Traugott U., Stone S.H. Suppression of chronic allergic encephalomyelitis: relevance to multiple sclerosis. Science. 201:1978;445-448.
    • (1978) Science , vol.201 , pp. 445-448
    • Raine, C.S.1    Traugott, U.2    Stone, S.H.3
  • 85
    • 0033455552 scopus 로고    scopus 로고
    • The role of CTLA-4 in tolerance induction and T cell differentiation in experimental autoimmune encephalomyelitis: Intravenous antigen administration
    • (in press)
    • Ratts, R.R., Arredondo, L.R., Bittner, P., Perrin, P.J., Lovett-Racke, A.E., Racke M.K., 1999a. The role of CTLA-4 in tolerance induction and T cell differentiation in experimental autoimmune encephalomyelitis: Intravenous antigen administration. Int. Immunol. (in press).
    • (1999) Int. Immunol.
    • Ratts, R.R.1    Arredondo, L.R.2    Bittner, P.3    Perrin, P.J.4    Lovett-Racke, A.E.5    Racke, M.K.6
  • 86
    • 0033455552 scopus 로고    scopus 로고
    • The role of CTLA-4 in tolerance induction and T cell differentiation in experimental autoimmune encephalomyelitis: Intraperitoneal antigen administration
    • (in press)
    • Ratts, R.R., Arredondo, L.R., Bittner, P., Perrin, P.J., Lovett-Racke, A.E., Racke, M.K., 1999b. The role of CTLA-4 in tolerance induction and T cell differentiation in experimental autoimmune encephalomyelitis: Intraperitoneal antigen administration. Int. Immunol. (in press).
    • (1999) Int. Immunol.
    • Ratts, R.R.1    Arredondo, L.R.2    Bittner, P.3    Perrin, P.J.4    Lovett-Racke, A.E.5    Racke, M.K.6
  • 87
    • 0343773445 scopus 로고    scopus 로고
    • IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease
    • Röcken M., Racke M., Shevach E.M. IL-4-induced immune deviation as antigen-specific therapy for inflammatory autoimmune disease. Immunol. Today. 17:1996;225-231.
    • (1996) Immunol. Today , vol.17 , pp. 225-231
    • Röcken, M.1    Racke, M.2    Shevach, E.M.3
  • 89
    • 0027398162 scopus 로고
    • Epidemiology of multiple sclerosis: A critical overview
    • Sadovnick A.D., Ebers G.C. Epidemiology of multiple sclerosis: a critical overview. Can. J. Neurol. Sci. 20:1993;17-29.
    • (1993) Can. J. Neurol. Sci. , vol.20 , pp. 17-29
    • Sadovnick, A.D.1    Ebers, G.C.2
  • 91
    • 0027473759 scopus 로고
    • B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro
    • Sansom D.M., Hall N.D. B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro. Eur. J. Immunol. 23:1993;295-298.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 295-298
    • Sansom, D.M.1    Hall, N.D.2
  • 92
    • 0022242651 scopus 로고
    • Autoaggressive T lymphocyte lines recognize the encephalitogenic region of myelin basic protein; In vitro selection from unprimed T cell populations
    • Schlüsener H., Wekerle H. Autoaggressive T lymphocyte lines recognize the encephalitogenic region of myelin basic protein; in vitro selection from unprimed T cell populations. J. Immunol. 135:1985;3128-3133.
    • (1985) J. Immunol. , vol.135 , pp. 3128-3133
    • Schlüsener, H.1    Wekerle, H.2
  • 93
    • 0027773017 scopus 로고
    • Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis: Evidence for programmed cell death as a mechanism to control inflammation in the brain
    • Schmied M., Breitschopf H., Gold R., Zischler H., Rothe G., Wekerle H., Lassmann H. Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis: evidence for programmed cell death as a mechanism to control inflammation in the brain. Am. J. Pathol. 143:1993;446-452.
    • (1993) Am. J. Pathol. , vol.143 , pp. 446-452
    • Schmied, M.1    Breitschopf, H.2    Gold, R.3    Zischler, H.4    Rothe, G.5    Wekerle, H.6    Lassmann, H.7
  • 94
    • 0031892792 scopus 로고    scopus 로고
    • Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation
    • Scholz C., Patton K.T., Anderson D.E., Freeman G.J., Hafler D.A. Expansion of autoreactive T cells in multiple sclerosis is independent of exogenous B7 costimulation. J. Immunol. 160:1998;1532-1538.
    • (1998) J. Immunol. , vol.160 , pp. 1532-1538
    • Scholz, C.1    Patton, K.T.2    Anderson, D.E.3    Freeman, G.J.4    Hafler, D.A.5
  • 95
    • 0016232349 scopus 로고
    • Critique of experimental trials of therapy in multiple sclerosis
    • Schumacher G.A. Critique of experimental trials of therapy in multiple sclerosis. Neurology. 24:1974;1010-1014.
    • (1974) Neurology , vol.24 , pp. 1010-1014
    • Schumacher, G.A.1
  • 96
    • 0031569258 scopus 로고    scopus 로고
    • Role of costimulators in T cell differentiation: Studies using antigen-presenting cells lacking expression of CD80 or CD86
    • Schweitzer A.N., Borriello F., Wong R.C.K., Abbas A.K., Sharpe A.H. Role of costimulators in T cell differentiation: studies using antigen-presenting cells lacking expression of CD80 or CD86. J. Immunol. 158:1997;2713-2722.
    • (1997) J. Immunol. , vol.158 , pp. 2713-2722
    • Schweitzer, A.N.1    Borriello, F.2    Wong, R.C.K.3    Abbas, A.K.4    Sharpe, A.H.5
  • 97
    • 0026077508 scopus 로고
    • Treatment of chronic relapsing experimental allergic encephalomyelitis with the intravenous administration of splenocytes coupled to encephalitogenic peptide 91-103 of myelin basic protein
    • Su X.-M., Sriram S. Treatment of chronic relapsing experimental allergic encephalomyelitis with the intravenous administration of splenocytes coupled to encephalitogenic peptide 91-103 of myelin basic protein. J. Neuroimmunol. 34:1991;181-190.
    • (1991) J. Neuroimmunol. , vol.34 , pp. 181-190
    • Su, X.-M.1    Sriram, S.2
  • 98
    • 0028867420 scopus 로고
    • Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing critical negative regulatory role of CTLA-4
    • Tivol E.A., Borriello F., Schweitzer A.N., Lynch W.P., Bluestone J.A., Sharpe A.H. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing critical negative regulatory role of CTLA-4. Immunity. 3:1995;541-547.
    • (1995) Immunity , vol.3 , pp. 541-547
    • Tivol, E.A.1    Borriello, F.2    Schweitzer, A.N.3    Lynch, W.P.4    Bluestone, J.A.5    Sharpe, A.H.6
  • 101
    • 0025602793 scopus 로고
    • Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity
    • Webb C., Morris C., Sprent J. Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell. 63:1990;1249-1256.
    • (1990) Cell , vol.63 , pp. 1249-1256
    • Webb, C.1    Morris, C.2    Sprent, J.3
  • 102
    • 0028809507 scopus 로고
    • Expression of costimulatory molecules B7-1 (CD-80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions
    • Windhagen A., Newcombe J., Dangond F., Strand C., Woodroofe M.N., Cuzner M.L., Hafler D.A. Expression of costimulatory molecules B7-1 (CD-80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions. J. Exp. Med. 182:1995;1985-1996.
    • (1995) J. Exp. Med. , vol.182 , pp. 1985-1996
    • Windhagen, A.1    Newcombe, J.2    Dangond, F.3    Strand, C.4    Woodroofe, M.N.5    Cuzner, M.L.6    Hafler, D.A.7
  • 103
    • 0028926223 scopus 로고
    • Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
    • Wucherpfennig K.W., Strominger J.L. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell. 80:1995;695-705.
    • (1995) Cell , vol.80 , pp. 695-705
    • Wucherpfennig, K.W.1    Strominger, J.L.2
  • 104
    • 0025246367 scopus 로고
    • The lymphocyte in experimental allergic encephalomyelitis
    • Zamvil S.S., Steinman L. The lymphocyte in experimental allergic encephalomyelitis. Annu. Rev. Immunol. 8:1990;579-621.
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 579-621
    • Zamvil, S.S.1    Steinman, L.2
  • 105
    • 0027319467 scopus 로고
    • Loss rather than down regulation of CD4+ T cells as a mechanism for remission from experimental allergic encephalomyelitis
    • Zeine R., Owens T. Loss rather than down regulation of CD4+ T cells as a mechanism for remission from experimental allergic encephalomyelitis. J. Neuroimmunol. 44:1993;193-198.
    • (1993) J. Neuroimmunol. , vol.44 , pp. 193-198
    • Zeine, R.1    Owens, T.2
  • 106
    • 0027957780 scopus 로고
    • Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
    • Zhang J., Markovic-Plese S., Lacet B., Raus J., Weiner H.L., Hafler D.A. Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. J. Exp. Med. 179:1994;973-984.
    • (1994) J. Exp. Med. , vol.179 , pp. 973-984
    • Zhang, J.1    Markovic-Plese, S.2    Lacet, B.3    Raus, J.4    Weiner, H.L.5    Hafler, D.A.6


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