Nuclear export of yeast signal recognition particle lacking Srp54p by the Xpo1p/Crm1p NES-dependent pathway

Current Biology

Volumn 10, Issue 20, 2000, Pages 1256-1264

  Ciufo, Leonora F ^a   Brown, Jeremy D ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034687215     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00743-0     Document Type: Article

References (47)

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4. Elongation arrest is a physiologically important function of signal recognition particle
5. Adenylation of small RNAs in human cells. Development of a cell-free system for accurate adenylation on the 3'-end of human signal recognition particle RNA
6. Nuclear export of signal recognition particle RNA is a facilitated process that involves the Alu sequence domain
7. The nucleolus: An old factory with unexpected capabilities
8. The nucleolus and the four ribonucleoproteins of translation
9. Like attracts like: Getting RNA processing together in the nucleus
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12. The signal recognition particle in S. cerevisiae
13. Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression
14. SEC65 gene product is a subunit of the yeast signal recognition particle required for its integrity
15. GTP binding and hydrolysis by the signal recognition particle during initiation of protein translocation
16. Transport of proteins and RNAs in and out of the nucleus
17. Yeast genetics to dissect the nuclear pore complex and nucleocytoplasmic trafficking
18. Transport between the cell nucleus and the cytoplasm
19. Identification and characterization of a yeast nucleolar protein that is similar to a rat liver nucleolar protein
20. Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores
21. A conditional allele of the novel repeat-containing yeast nucleoporin RATT/NUP159 causes both a rapid cessation of mRNA export and reversible clustering of nuclear pore complexes
22. Rna1p, a Ran/TC4 GTPase-activating protein, is required for nuclear import
23. A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in chromosome condensation
24. A conditional yeast mutant deficient in mRNA transport from the nucleus to cytoplasm
25. Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: Possible coupling of mRNA processing and chromatin structure
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27. + RNA transport and nuclear pore distribution
28. Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins
29. A novel in vivo assay reveals inhibition of ribosomal nuclear export in Rancycle and nucleoporin mutants
30. Exportin 1 (Crm1p) is an essential nuclear export factor
31. Crm1 is an export receptor for leucine-rich nuclear export signals
32. CRM1 is responsible for intracellular transport mediated by the nuclear export signal
33. The NES-Crm1p export pathway is not a major mRNA export route in Saccharomyces cerevisiae
34. A member of the Ran-binding protein family, Yrb2p, is involved in nuclear protein export
35. Yrb2p, a Nup2p-related yeast protein, has a functional overlap with Rna1p, a yeast Ran-GTPase-activating protein
36. Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue
37. Disruption of the YRB2 gene retards nuclear protein export, causing a profound mitotic delay, and can be rescued by overexpression of XPO1/CRM1
38. The most abundant small cytoplasmic RNA of Saccharomyces cerevisiae has an important function required for normal cell growth
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41. PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation
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43. Transcribed genes are localized according to chromosomal position within polarized Drosophila embryonic nuclei
44. Visualizing fluorescence in Drosophila - Optimal detection in thick specimens
45. Reconstitution of endoplesmic reticulum to Golgi transport in yeast: In vitro assay to cherecterise secretory mutants end functional transport vesicles
46. Isolation and characterization of nuclear envelopes from the yeast Saccharomyces
47. The S. cerevisiae SEC65 gene encodes a component of yeast signal recognition particle with homology to SRP19