Transcribed genes are localized according to chromosomal position within polarized Drosophila embryonic nuclei

Current Biology

Volumn 9, Issue 21, 1999, Pages 1263-1266

  Wilkie, Gavin S ^a   Shermoen, Antony W ^b   O'Farrell, Patrick H ^b   Davis, Ilan ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMOSOME; GENETIC ANALYSIS; LOCALIZATION; MESSENGER RNA;

DROSOPHILA; DROSOPHILA MELANOGASTER;

EID: 0033523949     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(99)80509-0     Document Type: Article

References (15)

1. Brown KE, Guest SS, Smale ST, Hanm K, Merkenschlager M, Fisher AG, et al.: Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell 1997, 91:845-854.
2. Brown KE, Baxter J, Graf D, Merkenschlager M, Fisher AG: Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division. Mol Cell 1999, 3:207-217.
3. Singer RH, Green MR: Compartmentalization of eukaryotic gene expression: Causes and effects. Cell 1997, 91:291 -294.
4. Marshall WF, Sedat JW: Nuclear architecture. In Genomic Imprinting, An Interdisciplinary Approach. Edited by Ohlsson R. Berlin: Springer-Verlag; 1999:283-301.
5. Wilkie GS, Davis I: High resolution and sensitive mRNA in situ hybridisation using fluorescent tyramide signal amplification. Technical Tips Online 1998, t01458 (http://www.biomednet.com/db/tto).
6. Marshall WF, Dernburg AF, Harmon B, Agard DA, Sedat JW: Specific interactions of chromatin with the nuclear envelope: Positional determination within the nucleus in Drosophila melanogaster. Mol Biol Cell 1996, 7:825-842.
7. Davis I, Francis-Lang H, Ish-Horowicz D: Mechanisms of intracellular transcript localization and export in early Drosophila embryos. Cold Spring Harbor Symp Quant Biol 1993, 58:793-798.
8. Andrulis ED, Neiman AM, Zappulla DC, Sternglanz R: Perinuclear localization of chromatin facilitates transcriptional silencing. Nature 1998, 394:592-595.
9. Croft JA, Bridger JM, Boyles S, Perry P, Teague P, Bickmore WA: Differences in the localization and morphology of chromosomes in the human nucleus. J Cell Biol 1999, 145:1119-1131.
10. Klingler M, Soong J, Butler B, Gergen JP: Disperse versus compact elements for the regulation of runt stripes in Drosophila. Dev Biol 1996, 177:73-84.
11. Shermoen AW, O'Farrell PH: Progression of the cell-cycle through mitosis leads to abortion of nascent transcripts. Cell 1991, 67:303-310.
12. Gemkow M, Verveer P, Arndt-Jovin D: Homologous association of the bithorax-complex during embryogenesis: Consequences for transvection in Drosophila melanogaster. Development 1998, 125:4541-4552.
13. Hama C, Ali Z, Kornberg TB: Region-specific recombination and expression are directed by portions of the Drosophila engrailed promoter. Genes Dev 1990, 4:1079-1093.
14. Davis I, Ish-Horowicz D: Apical localization of pair-rule transcripts requires 3′ sequences and limits protein diffusion in the Drosophila blastoderm embryo. Cell 1991, 67:927-940.
15. Dernburg AF, Sedat JW: Mapping three-dimensional chromosome architecture in situ. Meth Cell Biol 1998, 53:187.