Mechanism of topoisomerase II inhibition by staurosporine and other protein kinase inhibitors

Journal of Biological Chemistry

Volumn 271, Issue 42, 1996, Pages 26418-26423

  Lassota, Piotr ^a   Singh, Guyanand ^a   Kramer, Robert ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 PROPANEDIAMINE N,N' DIACETAMIDE N,N' DIACETIC ACID; ADENOSINE TRIPHOSPHATE; ADENYLYLIMIDODIPHOSPHATE; ANTINEOPLASTIC AGENT; CINNAMIC ACID DERIVATIVE; DNA TOPOISOMERASE (ATP HYDROLYSING); ESSENTIAL AMINO ACID; ETOPOSIDE; GENISTEIN; KINETOPLAST DNA; MALEIMIDE DERIVATIVE; MITOXANTRONE; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; STAUROSPORINE;

ARTICLE; COVALENT BOND; DNA ALKYLATION; DNA CLEAVAGE; DNA DRUG COMPLEX; DRUG DNA INTERACTION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ADENYLYL IMIDODIPHOSPHATE; ANIMALS; CINNAMATES; CRITHIDIA FASCICULATA; DNA; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; ETOPOSIDE; INDOLES; MALEIMIDES; PIPERAZINES; PROTEIN KINASE INHIBITORS; STAUROSPORINE;

EUKARYOTA;

EID: 0029911526     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.42.26418     Document Type: Article

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