Possible role of protein kinase C ζ in muscarinic receptor-induced proliferation of astrocytoma cells

Biochemical Pharmacology

Volumn 60, Issue 10, 2000, Pages 1457-1466

  Guizzetti, Marina ^a   Costa, Lucio G ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

132 1N1 astrocytoma cells; Cell proliferation; Muscarinic receptor; Protein kinase C

Indexed keywords

CARBACHOL; CELL DNA; G PROTEIN COUPLED RECEPTOR; INHIBITOR PROTEIN; ISOENZYME; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M5 RECEPTOR; PEPTIDE Z; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE D; PROTEIN KINASE C; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTOMA; ASTROCYTOMA CELL; CANCER GROWTH; CANCER INHIBITION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; DOSE TIME EFFECT RELATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; MITOGENESIS; PRIORITY JOURNAL; RECEPTOR BINDING; TRANSCRIPTION REGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ASTROCYTOMA; CELL DIVISION; HUMAN; MUSCARINIC AGONISTS; PHOSPHATIDIC ACIDS; PHOSPHOLIPASE D; PROTEIN KINASE C; RECEPTORS, MUSCARINIC; SUPPORT, U.S. GOV'T, P.H.S.; TUMOR CELLS, CULTURED;

EID: 0034670168     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00468-8     Document Type: Article

References (51)

1. Gutkind J.S., Crespo P., Xu N., Teramoto H., Coso O.A. The pathway connecting m2 receptors to the nucleus involves small GTP-binding proteins acting on divergent MAP kinase cascades. Life Sci. 60:1997;999-1006.
2. van Biesen T., Luttrell L.M., Hawes B.E., Lefkowitz R.J. Mitogenic signaling via G protein-coupled receptors. Endocr Rev. 17:1996;698-714.
3. Bonner T.I. Domains of muscarinic acetylcholine receptors that confer specificity to G protein coupling. Trends Pharmacol Sci. 13:1992;48-50.
4. Wess J. Molecular basis of muscarinic acetylcholine receptor function. Trends Pharmacol Sci. 14:1993;308-313.
5. Cohen R.I., Molina H.-E., Almazan G. Carbachol stimulates c-fos expression and proliferation in oligodendrocyte progenitors. Mol Brain Res. 43:1996;193-201.
6. Ashkenazi A., Ramachandran J., Capon D.J. Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes. Nature. 340:1989;146-150.
7. Fucile S., Napolitano M., Mattei E. Cholinergic stimulation of human microcytoma cell line H69. Biochem Biophys Res Commun. 230:1997;501-504.
8. Guizzetti M., Costa P., Peters J., Costa L.G. Acetylcholine as a mitogen Muscarinic receptor-mediated proliferation of rat astrocytes and human astrocytoma cells . Eur J Pharmacol. 297:1996;265-273.
9. Luthin G.R., Wang P., Zhou H., Dhanasekaran D., Ruggieri M.R. Role of m1 receptor-G protein coupling in cell proliferation in the prostate. Life Sci. 60:1997;963-968.
10. Rayford W., Noble M.J., Austenfeld M.A., Weigel J., Mebust W.K., Shah G.V. Muscarinic cholinergic receptors promote growth of human prostate cancer cells. Prostate. 30:1997;160-166.
11. Gutkind J.S., Novotny E.A., Brann M.R., Robbins K.C. Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes. Proc Natl Acad Sci USA. 88:1991;4703-4707.
12. Post G.R., Collins L.R., Kennedy E.D., Moskowitz S.A., Aragay A.M., Goldstein D., Brown J.H. Coupling of the thrombin receptor to G12 may account for selective effects of thrombin on gene expression and DNA synthesis in 1321N1 astrocytoma cells. Mol Biol Cell. 7:1996;1679-1690.
13. Gafni J., Munsch J.A., Lam T.H., Catlin M.C., Costa L.G., Molinski T.F., Pessah I.N. Xestospongins Potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor . Neuron. 19:1997;723-733.
14. Guizzetti M., Wei M., Costa L.G. The role of protein kinase C α and ε isozymes in DNA synthesis induced by muscarinic receptors in a glial cell line. Eur J Pharmacol. 359:1998;223-233.
15. ras and protein kinase C ζ in primary endothelial cells. J Biol Chem. 274:1999;13594-13603.
16. Diaz-Meco M.T., Lallena M.-J., Monjas A., Frutos S., Moscat J. Inactivation of the inhibitory κB protein kinase/nuclear factor κB pathway by Par-4 expression potentiates tumor necrosis factor α-induced apoptosis. J Biol Chem. 274:1999;19606-19612.
17. Sanz L., Sanchez P., Lallena M.-J., Diaz-Meco M.T., Moscat J. The interaction of p62 with RIP links the atypical PKCs to NF-κB activation. EMBO J. 18:1999;3044-3053.
18. Sontag E., Sontag J.-M., Garcia A. Protein phosphatase 2A is a critical regulator of protein kinase C ζ signaling targeted by SV40 small t to promote cell growth and NF-κB activation. EMBO J. 16:1997;5662-5671.
19. Berra E., Díaz-Meco M.T., Lozano J., Frutos S., Municio M.M., Sánchez P., Sanz L., Moscat J. Evidence for a role of MEK and MAPK during signal transduction by protein kinase C ζ EMBO J. 14:1995;6157-6163.
20. Schonwasser D.C., Marais R.M., Marshall C.J., Parker P.J. Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes. Mol Cell Biol. 18:1998;790-798.
21. Romanelli A., Martin K.A., Toker A., Blenis J. p70 S6 kinase is regulated by protein kinase C ζ and participates in a phosphoinositide 3-kinase-regulated signalling complex. Mol Cell Biol. 19:1999;2921-2928.
22. Bandyopadhyay G., Standaert M.L., Galloway L., Moscat J., Farese R.V. Evidence for involvement of protein kinase C (PKC)-ζ and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes. Endocrinology. 138:1997;4721-4731.
23. Tang S.H., Sharp G.W.G. Atypical protein kinase C isozyme zeta mediates carbachol-stimulated insulin secretion in RINm5F cells. Diabetes. 47:1998;905-912.
24. Laudanna C., Mochly-Rosen D., Liron T., Constantin G., Butcher E.C. Evidence of ζ protein kinase C involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis. J Biol Chem. 273:1998;30306-30315.
25. Shih S.C., Mullen A., Abrams K., Mukhopadhyay D., Claffey K.P. Role of protein kinase C isoforms in phorbol ester-induced vascular endothelial growth factor expression in human glioblastoma cells. J Biol Chem. 274:1999;15407-15414.
26. Díaz-Meco M.T., Municio M.M., Frutos S., Sanchez P., Lozano J., Sanz L., Moscat J. The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C. Cell. 86:1996;777-786.
27. Frutos S., Moscat J., Diaz-Meco M.T. Cleavage of ζ PKC but not λ/ιPKC by caspase-3 during UV-induced apoptosis. J Biol Chem. 274:1999;10765-10770.
28. Dominguez I., Diaz-Meco M.T., Municio M.M., Berra E., García de Herreros A., Cornet M.E., Sanz L., Moscat J. Evidence for a role of protein kinase C ζ subspecies in maturation of Xenopus laevis oocytes. Mol Cell Biol. 12:1992;3776-3783.
29. Berra E., Diaz-Meco M.T., Dominguez I., Municio M.M., Lozano J., Chapkin R.S., Moscat J. Protein kinase C ζ isoform is critical for mitogenic signal transduction. Cell. 74:1993;555-563.
30. Wellner M., Maasch C., Kupprion C., Lindschau C., Luft F.C., Haller H. The proliferative effect of vascular endothelial growth factor requires protein kinase C-alpha and protein kinase C-zeta. Arterioscler Thromb Vasc Biol. 19:1999;178-185.
31. Carlin S., Yang K.X.F., Donnelly R., Black J.L. Protein kinase C isoforms in human airway smooth muscle cells Activation of PKC-ζ during proliferation . Am J Physiol. 276:1999;L506-L512.
32. Montaner S., Ramos A., Perona R., Esteve P., Carnero A., Lacal J.C. Overexpression of PKC ζ in NIH3T3 cells does not induce cell transformation nor tumorigenicity and does not alter NFκB activity. Oncogene. 10:1995;2213-2220.
33. Crespo P., Mischak H., Gutkind J.S. Overexpression of mammalian protein kinase C ζ does not affect the growth characteristics of NIH 3T3 cells. Biochem Biophys Res Commun. 213:1995;266-272.
34. Limatola C., Schaap D., Moolenaar W.H., van Blitterswijk W.J. Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells Comparison with other protein kinase C isotypes and other acidic lipids . Biochem J. 304:1994;1001-1008.
35. Nakanishi H., Brewer K.A., Exton J.H. Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem. 268:1993;13-16.
36. Chou M.M., Hou W., Johnson J., Graham L.K., Lee M.H., Chen C.-S., Newton A.C., Schaffhausen B.S., Toker A. Regulation of protein kinase C ζ by PI 3-kinase and PDK-1. Curr Biol. 8:1998;1069-1077.
37. Allen B.G., Andrea J.E., Walsh M.P. Identification and characterization of protein kinase C ζ-immunoreactive proteins. J Biol Chem. 269:1994;29288-29298.
38. Marais R.M., Parker P.J. Purification and characterisation of bovine brain protein kinase C isotypes α, β and γ Eur J Biochem. 182:1989;129-137.
39. Guizzetti M., Costa L.G. Inhibition of muscarinic receptor-stimulated glial cell proliferation by ethanol. J Neurochem. 67:1996;2236-2245.
40. Majumdar M., Seasholtz T.M., Goldstein D., de Lanerolle P., Brown J.H. Requirement for Rho-mediated myosin light chain phosphorylation in thrombin-stimulated cell rounding and its dissociation from mitogenesis. J Biol Chem. 273:1998;10099-10106.
41. Martinson E.A., Trilivas I., Brown J.H. Rapid protein kinase C-dependent activation of phospholipase D leads to delayed 1,2-diglyceride accumulation. J Biol Chem. 265:1990;22282-22287.
42. Mitchell R., McCulloch D., Lutz E., Johnson M., MacKenzie C., Fennell M., Fink G., Zhou W., Sealfon S.C. Rhodopsin-family receptors associate with small G proteins to activate phospholipase D. Nature. 392:1998;411-414.
43. Gustavsson L. Phosphatidylethanol formation Specific effects of ethanol mediated via phospholipase D . Alcohol Alcohol. 30:1995;391-406.
44. Galve-Roperh I., Malpartida J.M., Haro A., Diaz-Laviada I. Addition of phosphatidylcholine-phospholipase C induces cellular redistribution and phosphorylation of protein kinase C ζ in C 6 glial cells. Neurosci Lett. 219:1996;68-70.
45. Galve-Roperh I., Haro A., Diaz-Laviada I. Ceramide-induced translocation of protein kinase C ζ in primary cultures of astrocytes. FEBS Lett. 415:1997;271-274.
46. Standaert M.L., Galloway L., Karnam P., Bandyopadhyay G., Moscat J., Farese R.V. Protein kinase C ζ as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport. J Biol Chem. 272:1997;30075-30082.
47. Duronio V., Scheid M.P., Ettinger S. Downstream signalling events regulated by phosphatidylinositol 3-kinase activity. Cell Signal. 10:1998;233-239.
48. Kotter K., Klein J. Ethanol inhibits astroglial cell proliferation by disruption of phospholipase D-mediated signaling. J Neurochem. 73:1999;2517-2523.
49. Baumgold J., Dyer K.D. Muscarinic receptor-mediated increase in ζ PKC expression in SK-N-SH human neuroblastoma cells. Neurochem Res. 19:1994;135-138.
50. 2 muscarinic receptors to membrane ion channels via phosphoinositide 3-kinase γ and atypical protein kinase C. J Biol Chem. 274:1999;13859-13864.
51. Chou M.M., Blenis J. The 70 kDa S6 kinase Regulation of a kinase with multiple roles in mitogenic signalling . Curr Opin Cell Biol. 7:1995;806-814.