Salmonella infection does not increase expression and activity of the high affinity IL-12 receptor

Journal of Immunology

Volumn 165, Issue 6, 2000, Pages 3324-3332

  Elhofy, A ^a   Marriott, I ^a   Bost, K L ^a  

^a UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12 RECEPTOR; MESSENGER RNA; STAT4 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; HELPER CELL; MACROPHAGE; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SALMONELLA; SALMONELLOSIS; SPLEEN; T LYMPHOCYTE;

SALMONELLA;

EID: 0034665102     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.6.3324     Document Type: Article

References (77)

1. Salmonella as an intracellular parasite
2. + dendritic cells initiating cytokine expression
3. Exploitation of mammalian host cell functions by bacterial pathogens
4. Endogenous and exogenous interleukin-12 augment the protective immune response in mice orally challenged with Salmonella dublin
5. Effect of interleukin 12 neutralization on host resistance and γ interferon production in mouse typhoid
6. Severe mycobacterial and Salmonella infections in interleukin-12 receptor-deficient patients
7. Capacity of recombinant γ interferon to activate macrophages for Salmonella-killing activity
8. Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency
9. IL-12 and IFN-γ in host defense against mycobacteria and Salmonella in mice and men
10. Inherited interleukin 12 deficiency in a child with bacille Calmette-Guerin and Salmonella enteritidis disseminated infection
11. Characterization of IL-12 receptor β1 chain (IL-12Rβ1)-deficient mice: IL-12Rβ1 is an essential component of the functional mouse IL-12 receptor
12. Molecular biology of interleukin-12 receptors
13. Cloning and characterization of a mouse IL-12 receptor-β component
14. A functional interleukin 12 receptor complex is composed of two β-type cytokine receptor subunits
15. Selective expression of an interleukin-12 receptor component by human T helper 1 cells
16. + T cells that expands in patients receiving interleukin-12
17. Regulation of the interleukin (IL)-12R β2 subunit expression in developing T helper 1 (Th1) and Th2 cells
18. Characterization of cytokine differential induction of STAT complexes in primary human T and NK cells
19. Biological function and distribution of human interleukin-12 receptor β chain
20. Autocrine regulation of IL-12 receptor expression is independent of secondary IFN-γ secretion and not restricted to T and NK cells
21. Regulation of the IL-12/IL-12R axis: A critical step in T-helper cell differentiation and effector function
22. Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes
23. Signal transduction by interleukin-12 and interleukin-2: A comparison and contrast
24. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
25. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
26. The role of Stat4 in species-specific regulation of Th cell development by type I IFNs
27. The role of interleukin-12 in acquired immunity to Mycobacterium tuberculosis infection
28. Recombinant interleukin 12 cures mice infected with Leishmania major
29. IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection
30. Interleukin 12 is effective treatment for an established systemic intracellular infection: Experimental visceral leishmaniasis
31. Interleukin-12 is required for control of the growth of attenuated aromatic-compound-dependent salmonellae in BALB/c mice: Role of γ interferon and macrophage activation
32. Interferon γ (IFN-γ) production by gut-associated lymphoid tissue and spleen following oral Salmonella typhimurium challenge
33. Generation of γ interferon responses in murine Peyer's patches following oral immunization
34. Salmonella typhimurium induces IFN-γ production in murine splenocytes: Role of natural killer cells and macrophages
35. Lymphokine mRNA expression by transplantable murine B lymphocytic malignancies: Tumor-derived IL-10 as a possible mechanism for modulating the anti-tumor response
36. In vivo induction of interleukin-12 mRNA expression after oral immunization with Salmonella dublin or the B subunit of Escherichia coli heat-labile enterotoxin
37. Thapsigargin and cyclopiazonic acid initiate rapid and dramatic increases of IL-6 mRNA expression and IL-6 secretion in murine peritoneal macrophages
38. Increased susceptibility of mice to Salmonella infection following in vivo treatment with the substance P antagonist, spantide II
39. T-cell enrichment by nonadherence to nylon
40. Limited interleukin-18 response in Salmonella-infected murine macrophages and in Salmonella-infected mice
41. Altered receptor expression and decreased sensitivity of T-cells to the stimulatory cytokines IL-2, IL-7 and IL-12 in HIV infection
42. Increased expression of IL-12 receptor mRNA in active pulmonary tuberculosis and sarcoidosis
43. In BALB/c mice, IL-4 production during the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease
44. 9-Tetrahydrocannabinol treatment suppresses immunity and early IFN-γ, IL-12, and IL-12 receptor β2 responses to Legionella pneumophila infection
45. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4
46. c-Maf Promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms
47. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines
48. Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella
49. Limited role of CD28-mediated signals in T helper subset differentiation
50. T helper subset differentiation in the absence of invariant chain
51. A critical role for IL-4 in regulating disease severity in experimental allergic encephalomyelitis as demonstrated in IL-4-deficient C57BL/6 mice and BALB/c mice
52. + TCR-αβ cells and IFN-γ in bacterial clearance independent of intracellular location
53. Th1 response in Salmonella typhimurium-infected mice with a high or low rate of bacterial clearance
54. - T lymphocytes induces increased immunity to experimental Salmonella typhimurium infections in rats
55. The adjuvant effect of interleukin-12 in a vaccine against Leishmania major
56. Role of γ interferon and tumor necrosis factor α in resistance to Salmonella typhimurium infection
57. Substance P-induced IL-12 production by murine macrophages
58. CD40 ligand/CD40 stimulation regulates the production of IFN-γ from human peripheral blood mononuclear cells in an IL- 12- and/or CD28-dependent manner
59. Toxoplasma gondii: Evidence for interleukin-12-dependent and- independent pathways of interferon-γ production induced by an attenuated parasite strain
60. Secondary response to Listeria infection requires IFN-γ but is partially independent of IL-12
61. Salmonella typhimurium induces epithelial IL-8 expression via Ca(2+)-mediated activation of the NF-κB pathway
62. Differential production of interleukin-12 mRNA by murine macrophages in response to viable or killed Salmonella spp
63. IL-1α and TNF-α are required for IL-12-induced development of Th1 cells producing high levels of IFN-γ in BALB/c but not C57BL/6 mice
64. Susceptibility of CBA/N mice to infection with Salmonella typhimurium: Influence of the X-linked gene controlling B lymphocyte function
65. Genetic control of in vitro natural cell-mediated activity against Salmonella typhimurium by intestinal and splenic lymphoid cells in mice
66. + T cells resulting in a state of unresponsiveness to IL-12
67. Differential regulation of the interleukin-12 receptor during the innate immune response to Leishmania major
68. In vivo IL-12 production and IL-12 receptors β1 and β2 mRNA expression in the spleen are differentially up-regulated in resistant B6 and susceptible A/J mice during early blood-stage Plasmodium chabaudi AS malaria
69. T-helper 1 and T-helper 2 cytokine responses in gut-associated lymphoid tissue following enteric reovirus infection
70. The interleukin-12/interleukin-12-receptor system: Role in normal and pathologic immune responses
71. Early events controlling T-helper cell differentiation: The role of the IL-12 receptor
72. Genetically resistant (Ityr) and susceptible (Itys) congenic mouse strains show similar cytokine responses following infection with Salmonella dublin
73. In vivo production and function of IL-12 p40 homodimers
74. Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation
75. Cholera toxin and Salmonella typhimurium induce different cytokine profiles in the gastrointestinal tract
76. Interleukin-12: A bridge between innate resistance and adaptive immunity with a role in infection and acquired immunodeficiency
77. Interleukin-12: A proinflammatory cytokine with immuno-regulatory functions that bridge innate resistance and antigen-specific adaptive immunity