-
1
-
-
0028049247
-
The adjuvant effect of interleukin-12 in a vaccine against Leishmania majoi
-
Afonso, L. C. C., T. M. Scharton, L. Q. Vieira, M. Wysocka, G. Trinchieri, and P. Scott, 1994. The adjuvant effect of interleukin-12 in a vaccine against Leishmania majoi. Science 263:235-237.
-
(1994)
Science
, vol.263
, pp. 235-237
-
-
Afonso, L.C.C.1
Scharton, T.M.2
Vieira, L.Q.3
Wysocka, M.4
Trinchieri, G.5
Scott, P.6
-
2
-
-
0029099391
-
Effects of IL-12 on immune responses to microbial infections: A key mediator in regulating disease out-come
-
Biron, C. A., and R. T. Gazzinelli. 1995 Effects of IL-12 on immune responses to microbial infections: a key mediator in regulating disease out-come. Curr. Opin Immunol 7:485-496.
-
(1995)
Curr. Opin Immunol
, vol.7
, pp. 485-496
-
-
Biron, C.A.1
Gazzinelli, R.T.2
-
3
-
-
0028944532
-
In vivo induction of interleukin-12 mRNA expression after oral immunization with Salmonella dublin or the B subunit of Escherichia coli heat-labile enterotoxin
-
Bost, K. L., and J. D. Clements. 1995 In vivo induction of interleukin-12 mRNA expression after oral immunization with Salmonella dublin or the B subunit of Escherichia coli heat-labile enterotoxin. Infect Immun 63:1076-1083.
-
(1995)
Infect Immun
, vol.63
, pp. 1076-1083
-
-
Bost, K.L.1
Clements, J.D.2
-
4
-
-
0029879162
-
Differential production of interleukin-12 mRNA by murine macrophages in response to viable or killed Salmonella spp
-
Chong, C., K. L. Bost, and J. D. Clements. 1996. Differential production of interleukin-12 mRNA by murine macrophages in response to viable or killed Salmonella spp. Infect. Immun. 64:1154-1160.
-
(1996)
Infect. Immun.
, vol.64
, pp. 1154-1160
-
-
Chong, C.1
Bost, K.L.2
Clements, J.D.3
-
5
-
-
0028947010
-
The role of IL-12 in acquired immunity to Mycobacterium tuberculosis infection
-
Cooper, A. M., A. D. Roberts, E. R. Rhoades, J. E. Callahan, D. M. Getzy, and I. M. Orme. 1995. The role of IL-12 in acquired immunity to Mycobacterium tuberculosis infection Immunology 84:423-432.
-
(1995)
Immunology
, vol.84
, pp. 423-432
-
-
Cooper, A.M.1
Roberts, A.D.2
Rhoades, E.R.3
Callahan, J.E.4
Getzy, D.M.5
Orme, I.M.6
-
6
-
-
0029078676
-
IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection
-
Flynn, J. L., M. M. Goldstein, K. J. Triebold, J. Sypek, S. Wolf, and B. R. Bloom. 1995 IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection J. Immunol. 155:2515-2524.
-
(1995)
J. Immunol.
, vol.155
, pp. 2515-2524
-
-
Flynn, J.L.1
Goldstein, M.M.2
Triebold, K.J.3
Sypek, J.4
Wolf, S.5
Bloom, B.R.6
-
7
-
-
0027264849
-
IL-12 is required for the T-lymphocyte-independent induction of interferon-gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts
-
Gazzinelli, R. T., S. Hieny, T. A. Wynn, S. Wolf, and A. Sher. 1993. IL-12 is required for the T-lymphocyte-independent induction of interferon-gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts Proc. Natl. Acad Sci USA 90:6115-6119.
-
(1993)
Proc. Natl. Acad Sci USA
, vol.90
, pp. 6115-6119
-
-
Gazzinelli, R.T.1
Hieny, S.2
Wynn, T.A.3
Wolf, S.4
Sher, A.5
-
8
-
-
0025808629
-
Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor
-
Gubler, U., A. O. Chua, D. S. Schoenhaut, C. M. Dwyer, W. McComas, R. Motyka, N. Nabavi, A. G. Wolitzky, P. M. Quinn. P. C. Familletti, and M. K. Gately. 1991. Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor. Proc Natl. Acad. Sci USA 88:4143-4147.
-
(1991)
Proc Natl. Acad. Sci USA
, vol.88
, pp. 4143-4147
-
-
Gubler, U.1
Chua, A.O.2
Schoenhaut, D.S.3
Dwyer, C.M.4
McComas, W.5
Motyka, R.6
Nabavi, N.7
Wolitzky, A.G.8
Quinn, P.M.9
Familletti, P.C.10
Gately, M.K.11
-
9
-
-
0027528795
-
Recombinant IL-12 cures mice infected with Letshmama major
-
Heinzel, F. P., D. S. Schoenhaut, R. M. Rerko, L. E. Rosser, and M. K. Gately. 1993. Recombinant IL-12 cures mice infected with Letshmama major. J. Exp. Med. 177:1505-1509.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1505-1509
-
-
Heinzel, F.P.1
Schoenhaut, D.S.2
Rerko, R.M.3
Rosser, L.E.4
Gately, M.K.5
-
10
-
-
0027336689
-
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
-
Hsieh, C. S., S. E. Macatonia, C. S. Tripp, S. F. Wolf, A. O'Garra, and K. M. Murphy. 1993. Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages. Science 260:547-549
-
(1993)
Science
, vol.260
, pp. 547-549
-
-
Hsieh, C.S.1
Macatonia, S.E.2
Tripp, C.S.3
Wolf, S.F.4
O'Garra, A.5
Murphy, K.M.6
-
11
-
-
0024346776
-
Pathogenesis and immunity in murine salmonellosis
-
Hsu, H. S. 1989. Pathogenesis and immunity in murine salmonellosis. Microbiol. Rev. 53:390-409.
-
(1989)
Microbiol. Rev.
, vol.53
, pp. 390-409
-
-
Hsu, H.S.1
-
12
-
-
0028272528
-
Production of gamma Interferon by natural killer cells from Taxoplasma gondit-infected SCID mice
-
Hunter, C. A., C. S. Subauste, V. H. Van Cleave, and J. S. Remington. 1994. Production of gamma Interferon by natural killer cells from Taxoplasma gondit-infected SCID mice. Infect Immun. 62:2818-2824.
-
(1994)
Infect Immun.
, vol.62
, pp. 2818-2824
-
-
Hunter, C.A.1
Subauste, C.S.2
Van Cleave, V.H.3
Remington, J.S.4
-
13
-
-
0028348030
-
IL-12 enhances murine survival against acute toxoplasmosis
-
Khan, I. A., T. Matsuura, and L. H. Kasper. 1994. IL-12 enhances murine survival against acute toxoplasmosis. Infect. Immun 62:1639-1642.
-
(1994)
Infect. Immun
, vol.62
, pp. 1639-1642
-
-
Khan, I.A.1
Matsuura, T.2
Kasper, L.H.3
-
14
-
-
0024467154
-
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes
-
Kobayashi, M., L. Fitz, M. Ryan, R. M. Hewick, S. C. Clark, S. Chan, R. London, F. Sherman, B. Perussia, and G. Trinchieri. 1989. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes J. Exp. Med. 170:827-845
-
(1989)
J. Exp. Med.
, vol.170
, pp. 827-845
-
-
Kobayashi, M.1
Fitz, L.2
Ryan, M.3
Hewick, R.M.4
Clark, S.C.5
Chan, S.6
London, R.7
Sherman, F.8
Perussia, B.9
Trinchieri, G.10
-
15
-
-
0028265155
-
IL-12 induces stable priming for interferon gamma production during differentiation of human T helper (Th) cells and transient interferon-gamma production in established Th2 cell clones
-
Manetti, R., F. Gerosa, M. G. Giudizi, R. Biagiotti, P. Parronchi, M.-P. Piccinni, S. Sampognaro, E. Maggi, S. Romagnani, and G. Trinchieri. 1994. IL-12 induces stable priming for interferon gamma production during differentiation of human T helper (Th) cells and transient interferon-gamma production in established Th2 cell clones. J. Exp. Med 179:1273-1283.
-
(1994)
J. Exp. Med
, vol.179
, pp. 1273-1283
-
-
Manetti, R.1
Gerosa, F.2
Giudizi, M.G.3
Biagiotti, R.4
Parronchi, P.5
Piccinni, M.-P.6
Sampognaro, S.7
Maggi, E.8
Romagnani, S.9
Trinchieri, G.10
-
16
-
-
0027409793
-
Natural killer cell stimulatory factor (interleukin-12) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing cells
-
Manetti, R., P. Parronchi, M. G. Giudizi, M. P. Piccinni, E. Maggi, G. Trinchieri, and S. Romagnani. 1993. Natural killer cell stimulatory factor (interleukin-12) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4 producing cells. J. Exp. Med. 177: 1199-1204
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1199-1204
-
-
Manetti, R.1
Parronchi, P.2
Giudizi, M.G.3
Piccinni, M.P.4
Maggi, E.5
Trinchieri, G.6
Romagnani, S.7
-
17
-
-
0027200981
-
The p40 subunit of IL-12 inhibits bioactivity of the IL-12 heterodimer
-
Mattner, R., S. Fischer, S. Guckes, S. Jin, H. Kaulen, E. Schmitt, E. Rude, and T. Germann. 1993. The p40 subunit of IL-12 inhibits bioactivity of the IL-12 heterodimer. Eur. J. Immunol. 23:2202-2208.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 2202-2208
-
-
Mattner, R.1
Fischer, S.2
Guckes, S.3
Jin, S.4
Kaulen, H.5
Schmitt, E.6
Rude, E.7
Germann, T.8
-
18
-
-
0028950126
-
Interleukin-12 is effective treatment for an established systemic intracellular infection: Experimental visceral leishmaniasis
-
Murray, H. W., and J. Hariprashad. 1995. Interleukin-12 is effective treatment for an established systemic intracellular infection: experimental visceral leishmaniasis. J. Exp. Med. 181:387-391.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 387-391
-
-
Murray, H.W.1
Hariprashad, J.2
-
19
-
-
0028266819
-
Effects of IL-12 on the response and susceptibility to experimental viral infections
-
Orange, J. S., S. F. Wolf, and C. A. Biron. 1994. Effects of IL-12 on the response and susceptibility to experimental viral infections. J. Immunol. 152: 1253-1264.
-
(1994)
J. Immunol.
, vol.152
, pp. 1253-1264
-
-
Orange, J.S.1
Wolf, S.F.2
Biron, C.A.3
-
20
-
-
0027191230
-
Salmonella typhimurium induces interferon-gamma production in murine splenocytes
-
Ramarathinam, L., D. W. Neisel, and G. R. Klimpel. 1993. Salmonella typhimurium induces interferon-gamma production in murine splenocytes J. Immunol 150:3973-3981.
-
(1993)
J. Immunol
, vol.150
, pp. 3973-3981
-
-
Ramarathinam, L.1
Neisel, D.W.2
Klimpel, G.R.3
-
21
-
-
0029021419
-
IL-12 stimulates an antiviral type 1 cytokine response but lacks adjuvant activity in interferon gamma receptor deficient mice
-
Schijns, V. E. C. J., B. L. Haagmans, and M. C. Horzinek. 1995. IL-12 stimulates an antiviral type 1 cytokine response but lacks adjuvant activity in interferon gamma receptor deficient mice. J. Immunol 155:2525-2532
-
(1995)
J. Immunol
, vol.155
, pp. 2525-2532
-
-
Schijns, V.E.C.J.1
Haagmans, B.L.2
Horzinek, M.C.3
-
22
-
-
0027177008
-
IL-12: Initiation cytokine for cell-mediated immunity
-
Scott, P. 1993. IL-12: initiation cytokine for cell-mediated immunity. Science 260:496-497.
-
(1993)
Science
, vol.260
, pp. 496-497
-
-
Scott, P.1
-
23
-
-
0027491655
-
IL-12 acts directly on CD4+ T cells to enhance priming for gamma-interferon production and diminishes IL-4 inhibition of such priming
-
Seder, R. A., R. Gazzinelli, A. Sher, and W. E. Paul. 1993 IL-12 acts directly on CD4+ T cells to enhance priming for gamma-interferon production and diminishes IL-4 inhibition of such priming. Proc. Natl. Acad. Sci. USA 90: 10188-10192.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10188-10192
-
-
Seder, R.A.1
Gazzinelli, R.2
Sher, A.3
Paul, W.E.4
-
24
-
-
0025028960
-
Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells
-
Stern, A. S., F. J. Podlaski, J. D. Hulmes, Y. E. Pan, P. M. Quinn, A. G. Wolitsky, C. Familletti, D. L. Stremlo, T. Truitt, R. Chizzonite, and M. K. Gately. 1990. Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 87:6808-6812.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 6808-6812
-
-
Stern, A.S.1
Podlaski, F.J.2
Hulmes, J.D.3
Pan, Y.E.4
Quinn, P.M.5
Wolitsky, A.G.6
Familletti, C.7
Stremlo, D.L.8
Truitt, T.9
Chizzonite, R.10
Gately, M.K.11
-
25
-
-
0027309318
-
Resolution of cutaneous leishmaniasis: Interleukin-12 initiates a protective T helper type 1 immune response
-
Sypek, J. P., C. L. Chung, S. E. H. Mayor, J. M. Subramanyam, S. J. Goldman, D. S. Sieburth, S. F. Wolf, and R. G. Schaub. 1993 Resolution of cutaneous leishmaniasis: interleukin-12 initiates a protective T helper type 1 immune response. J. Exp. Med. 177:1797-1802.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1797-1802
-
-
Sypek, J.P.1
Chung, C.L.2
Mayor, S.E.H.3
Subramanyam, J.M.4
Goldman, S.J.5
Sieburth, D.S.6
Wolf, S.F.7
Schaub, R.G.8
-
26
-
-
0028209541
-
Neutralization of IL-12 decreases resistance to Listena in SCID and C.B-17 mice. Reversal by gamma-interferon
-
Tripp, C. S., M. K. Gately, J. Hakimi, P. Ling, and E. R. Unanue. 1994. Neutralization of IL-12 decreases resistance to Listena in SCID and C.B-17 mice. Reversal by gamma-interferon. J. Immunol. 152:1883-1887
-
(1994)
J. Immunol.
, vol.152
, pp. 1883-1887
-
-
Tripp, C.S.1
Gately, M.K.2
Hakimi, J.3
Ling, P.4
Unanue, E.R.5
-
27
-
-
0028359087
-
Infection with Leishmania major induces interleukin-12 production in vivo
-
Vieira, L. Q., B. D. Hondowicz, L. C. C. Afonso, M. Wysocka, G. Trinchieri, and P. Scott. 1994 Infection with Leishmania major induces interleukin-12 production in vivo. Immunol. Lett. 40:157-161.
-
(1994)
Immunol. Lett.
, vol.40
, pp. 157-161
-
-
Vieira, L.Q.1
Hondowicz, B.D.2
Afonso, L.C.C.3
Wysocka, M.4
Trinchieri, G.5
Scott, P.6
-
28
-
-
0025875022
-
Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells
-
Wolf, S. F., P. A. Temple, M. Kobayashe, D. Young, M. Dicig, L. Lowe, R. Dzialo, L. Fitz, C. Ferenz, R. M. Hewick, K. Kelleher, S. H. Herrmann, S. C. Clark, L. Azzoni, S. H. Chan, G. Trinchieri, and B. Perussia. 1991. Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. J. Immunol. 146: 3074-3081
-
(1991)
J. Immunol.
, vol.146
, pp. 3074-3081
-
-
Wolf, S.F.1
Temple, P.A.2
Kobayashe, M.3
Young, D.4
Dicig, M.5
Lowe, L.6
Dzialo, R.7
Fitz, L.8
Ferenz, C.9
Hewick, R.M.10
Kelleher, K.11
Herrmann, S.H.12
Clark, S.C.13
Azzoni, L.14
Chan, S.H.15
Trinchieri, G.16
Perussia, B.17
-
29
-
-
0028987562
-
Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice
-
Wysocka, M., M. Kubin, L. Q. Vieira, L. Ozmen, G. Garotta, P. Scott, and G. Trinchieri. 1995. Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. Eur. J. Immunol. 25:672-676.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 672-676
-
-
Wysocka, M.1
Kubin, M.2
Vieira, L.Q.3
Ozmen, L.4
Garotta, G.5
Scott, P.6
Trinchieri, G.7
-
30
-
-
0028960641
-
Endogenous interleukin-12 is involved in resistance to Brucella abortus infection
-
Zhan, Y., and C. Cheers. 1995. Endogenous interleukin-12 is involved in resistance to Brucella abortus infection. Infect. Immun. 63:1387-1390.
-
(1995)
Infect. Immun.
, vol.63
, pp. 1387-1390
-
-
Zhan, Y.A.1
Cheers, C.2
|