Gastrointestinal safety of nitric oxide-derived aspirin is related to inhibition of ICE-like cysteine proteases in rats

Gastroenterology

Volumn 116, Issue 5, 1999, Pages 1089-1106

  Fiorucci, S ^a   Antonelli, E ^a   Santucci, L ^a   Morelli, O ^a   Miglietti, M ^a   Federici, B ^a   Mannucci, R ^a   Del Soldato, P ^a   Morelli, A ^a  

^a POLICLINICO MONTELUCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID 3 (NITROXYMETHYL)PHENYL ESTER; CASPASE; CYCLIC GMP; CYSTEINE PROTEINASE; DNA NUCLEOTIDYLEXOTRANSFERASE; INTERLEUKIN 1BETA CONVERTING ENZYME; MONOCLONAL ANTIBODY; NITRIC OXIDE; NONSTEROID ANTIINFLAMMATORY AGENT; TUMOR NECROSIS FACTOR ALPHA RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; DOSE RESPONSE; DRUG INDUCED DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUOROMETRY; GASTROINTESTINAL TOXICITY; GEL ELECTROPHORESIS; INFLAMMATION; LONG TERM CARE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; STOMACH DISEASE; STOMACH MUCOSA;

EID: 0032907875     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(99)70012-0     Document Type: Article

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