Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain

EMBO Journal

Volumn 19, Issue 6, 2000, Pages 1195-1206

  Barbato, G ^b   Cicero, D O ^b   Cordier, F ^a   Narjes, F ^b   Gerlach, B ^b   Sambucini, S ^b   Grzesiek, S ^a   Matassa, V G ^b   De Francesco, R ^b   Bazzo, R ^b  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b IRBM   (Italy)

Author keywords

Hepatitis C virus; NS3; Serine protease; Viral hydrolases; ketoacid

Indexed keywords

CHYMOTRYPSIN; ENZYME INHIBITOR; SERINE PROTEINASE; SOLVENT; VIRUS ENZYME;

AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE; HYDROGEN BOND; LIFE CYCLE; NONHUMAN; PRIORITY JOURNAL;

CYTOMEGALOVIRUS; HEPATITIS C VIRUS; SEMLIKI FOREST VIRUS;

EID: 0034654305     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.6.1195     Document Type: Article

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