Structure of semliki forest virus core protein

Proteins: Structure, Function and Genetics

Volumn 27, Issue 3, 1997, Pages 345-359

  Choi, Hok Kin ^a,c   Lu, Guoguang ^a,d   Lee, Sukyeong ^a   Wengler, Gerd ^b   Rossmann, Michael G ^a  

^a PURDUE UNIVERSITY   (United States)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c DUPONT COMPANY   (United States)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

alphavirus structure; autocatalysis; capsid assembly; conformational changes; Semliki Forest virus capsid protein

Indexed keywords

CORE PROTEIN; DIMER; MONOMER; VIRUS PROTEIN;

ALPHA VIRUS; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CATALYSIS; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; SEMLIKI FOREST ALPHAVIRUS; VIRUS ASSEMBLY; VIRUS CAPSID;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; VIRAL CORE PROTEINS; VIRAL ENVELOPE PROTEINS;

ALPHAVIRUS; INSECTA; MIRIDAE; RABBIT FIBROMA VIRUS; SEMLIKI FOREST VIRUS; SINDBIS VIRUS;

EID: 0030890291     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(199703)27:3<345::AID-PROT3>3.0.CO;2-C     Document Type: Article

References (43)

1. Strauss, J.H., Strauss, E.G. The alphaviruses: Gene expression, replication, and evolution. Microbiol. Rev. 58: 491-562, 1994.
2. Shope, R.E. Medical significance of togaviruses: An overview of diseases caused by togaviruses in man and in domestic and wild vertebrate animals. In: "The Togaviruses. Biology, Structure, Replication." Schlesinger, R.W. (ed.) New York: Academic Press, 1980:47-82.
3. Fuller, S.D., Berriman, J.A., Butcher, S.J., Gowen, B.E. Low pH induces swiveling of the glycoprotein heterodimers in the Semliki Forest virus spike complex. Cell 81:715-725, 1995.
4. Cheng, R.H., Kuhn, R.J., Olson, N.H., Rossmann, M.G., Choi, H.K., Smith, T.J., Baker, T.S. Nucleocapsid and glycoprotein organization in an enveloped virus. Cell 80:621-630, 1995.
5. Strauss, E.G., Strauss, J.H. Structure and replication of the Alphavirus genome. In: "The Togaviridae and Flaviviridae." Schlesinger, S. , Schlesinger, M.J. (eds.) New York: Plenum, 1986:35-90.
6. Hahn, C.S., Strauss, E.G., Strauss, J.H. Sequence analysis of three Sindbis virus mutants temperature-sensitive in the capsid protein autoprotease. Proc. Natl. Acad. Sci. USA 82:4648-4652, 1985.
7. Melancon, P., Garoff, H. Processing of the Semliki Forest virus structural polyprotein: Role of the capsid protease. J. Virol. 61:1301-1309, 1987.
8. Choi, H.K., Tong, L., Minor, W., Dumas, P., Boege, U., Rossmann, M.G., Wengler, G. Structure of Sindbis virus core protein reveals a chymotrypsin-like serine proteinase and the organization of the virion. Nature 354:37-43, 1991.
9. Tong, L., Choi, H.K., Minor, W., Rossmann, M.G. The structure determination of Sindbis virus core protein using isomorphous replacement and molecular replacement averaging between two crystal forms. Acta Crystallogr. A48: 430-442, 1992.
10. Hahn, C.S., Strauss, J.H. Site-directed mutagenesis of the proposed catalytic amino acids of the Sindbis virus capsid protein autoprotease. J. Virol. 64:3069-3073, 1990.
11. Tong, L., Wengler, G., Rossmann, M.G. Refined structure of Sindbis virus core protein and comparison with other chymotrypsin-like serine proteinase structures. J. Mol. Biol. 230:228-247, 1993.
12. Shirako, Y., Niklasson, B., Dalrymple, J.M., Strauss, E.G., Strauss, J.H. Structure of the Ockelbo virus genome and its relationship to other Sindbis viruses. Virology 182: 753-764, 1991.
13. Levinson, R.S., Strauss, J.H., Strauss, E.G. Complete sequence of the genomic RNA of O'Nyong-nyong virus and its use in the construction of alphavirus phylogenetic trees. Virology 175:110-123, 1990.
14. Kinney, R.M., Johnson, B.J.B., Brown, V.L., Trent, D.W. Nucleotide sequence of the 26S mRNA of the virulent Trinidad donkey strain of Venezuelan equine encephalitis virus and deduced sequence of the encoded structural proteins. Virology 152:400-413, 1986.
15. Hahn, C.S., Lustig, S., Strauss, E.G., Strauss, J.H. Western equine encephalitis virus is a recombinant virus. Proc. Natl. Acad. Sci. USA 85:5997-6001, 1988.
16. Garoff, H., Frischauf, A.-M., Simons, K., Lehrach, H., Delius, H. The capsid protein of Semliki Forest virus has clusters of basic amino acids and proteins in its amino-terminal region. Proc. Natl. Acad. Sci. USA 77:6376-6380, 1980.
17. Faragher, S.G., Meek, A.D.J., Rice, C.M., Dalgarno, L. Genome sequences of a mouse-avirulent and a mouse-virulent strain of Ross River virus. Virology 163:509-526, 1988.
18. Chang, G.-J., Trent, D.W. Nucleotide sequence of the genome region encoding the 26S mRNA of eastern equine encephalomyelitis virus and the decoded amino acid sequence of the viral structural proteins. J. Gen. Virol. 68: 2129-2142, 1987.
19. Boege, U., Wengler, G., Wengler, G., Wittmann-Liebold, B. Primary structure of the core proteins of the alphaviruses Semliki Forest virus and Sindbis virus. Virology 113:293-303, 1981.
20. Zhao, H., Lindqvist, B., Garoff, H., von Bonsdorff, C., Liljeström, P. A tyrosine-based motif in the cytoplasmic domain of the alphavirus envelope protein is essential for budding. EMBO J. 13:4204-4211, 1994.
21. Lee, H., Brown, D.T. Mutations in an exposed domain of Sindbis virus capsid protein result in the production of noninfectious virions and morphological variants. Virology 202:390-400, 1994.
22. Metsikkö, K., Garoff, H. Oligomers of the cytoplasmic domain of the p62/E2 membrane protein of Semliki Forest virus bind to the nucleocapsid in vitro. J. Virol. 64:4678-4683, 1990.
23. Vaux, D.J.T., Helenius, A., Mellman, I. Spike-nucleocapsid interaction in Semliki Forest virus reconstructed using network antibodies. Nature 336:36-42, 1988.
24. Skoging, U., Vihinen, M., Nilsson, L., Liljeström, P. Aromatic interactions define the binding of the alphavirus spike to its nucleocapsid. Structure 4:519-529, 1996.
25. Lee, S., Owen, K.E., Choi, H.K., Lee, H., Lu, G., Wengler, G., Brown, D.T., Rossmann, M.G., Kuhn, R.J. Identification of a protein binding site on the surface of the alpha-virus nucleocapsid and its implication in virus assembly. Structure 4:531-541, 1996.
26. Kabsch, W. Evaluation of single-crystal x-ray diffraction data from a position-sensitive detector. J. Appl. Crystallogr. 21:916-924, 1988.
27. Matthews, B.W. Solvent content of protein crystals. J. Mol. Biol. 33:491-497, 1968.
28. Ulmanen, I., Söderlund, H., Kääriäinen, L. Semliki Forest virus capsid protein associates with the 60S ribosomal sub-unit in infected cells. J. Virol. 20:203-210, 1976.
29. Rossmann, M.G., Blow, D.M. The detection of sub-units within the crystallographic asymmetric unit. Acta Crystallogr. 15:24-31, 1962.
30. Tong, L., Rossmann, M.G. The locked rotation function. Acta Crystallogr. A46:783-792, 1990.
31. Tong, L., Rossmann, M.G. Patterson-map interpretation with noncrystallographic symmetry. J. Appl. Crystallogr. 26:15-21, 1993.
32. Rossmann, M.G. The molecular replacement method. Acta Crystallogr. A46:73-82, 1990.
33. Brünger, A.T., Kuriyan, J., Karplus, M. Crystallographic R factor refinement by molecular dynamics. Science 235: 458-460, 1987.
34. Navaza, J. AMoRe: an automated package for molecular replacement. Acta Crystallogr. A50:157-163, 1994.
35. Engh, R.A., Huber, R. Accurate bond and angle parameters for x-ray protein structure refinement. Acta Crystallogr. A47:392-400, 1991.
36. Crowther, R.A. The fast rotation function. In: "The Molecular Replacement Method." Rossmann, M.G. (ed.) New York: Gordon & Breach, 1972:173-178.
37. Choi, H.K., Lee, S., Zhang, Y.P., McKinney, B.R., Wengler, G., Rossmann, M.G., Kuhn, R.J. Structural analysis of Sindbis virus capsid mutants involving assembly and catalysis. J. Mol. Biol. 262:151-167, 1996.
38. Boege, U., Cygler, M., Wengler, G., Dumas, P., Tsao, J., Luo, M., Smith, T.J., Rossmann, M.G. Sindbis virus core protein crystals. J. Mol. Biol. 208:79-82, 1989.
39. Coombs, K., Brown, D.T. Topological organization of Sindbis virus capsid protein in isolated nucleocapsids. Virus Res. 7:131-149, 1987.
40. Chapman, M.S. Mapping the surface properties of macromolecules. Prot. Sci. 2:459-469, 1993.
41. Rossmann, M.G., Palmenberg, A.C. Conservation of the putative receptor attachment site in picornaviruses. Virology 164:373-382, 1988.
42. Rossmann, M.G. Viral cell recognition and entry. Prot. Sci. 3:1712-1725, 1994.
43. Nicholls, A., Sharp, K.A., Honig, B. Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 11:281-296, 1991.