Mechanistic role of an NS4A peptide cofactor with the truncated NS3 protease of hepatitis C virus: Elucidation of the NS4A stimulatory effect via kinetic analysis and inhibitor mapping

Biochemistry

Volumn 36, Issue 31, 1997, Pages 9340-9348

  Landro, James A ^a   Raybuck, Scott A ^a   Luong, Yu Ping C ^a   O'Malley, Ethan T ^a   Harbeson, Scott L ^a   Morgenstern, Kurt A ^a   Rao, Govinda ^a   Livingston, David J ^a  

^a VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CHRONIC HEPATITIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; GENE MAPPING; HEPATITIS C; HEPATITIS C VIRUS; HYDROPHOBICITY; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN PROCESSING;

AMINO ACID SEQUENCE; KINETICS; MOLECULAR SEQUENCE DATA; PEPTIDES; SERINE ENDOPEPTIDASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; VIRAL NONSTRUCTURAL PROTEINS;

CANIDAE; FELIS CATUS; HEPATITIS C VIRUS;

EID: 0030871616     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi963054n     Document Type: Article

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