메뉴 건너뛰기




Volumn 12, Issue 2, 1998, Pages 139-146

HIV-1 p24 but not proviral load is increased in the intestinal mucosa compared with the peripheral blood in HIV-infected patients

Author keywords

HIV antigen; Intestinal mucosa; Nef; p24; Polymerase chain reaction; Viral load

Indexed keywords

GAG PROTEIN; VIRUS DNA;

EID: 6844258844     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199802000-00003     Document Type: Article
Times cited : (38)

References (36)
  • 1
    • 0030578662 scopus 로고    scopus 로고
    • Gastrointestinal manifestations of HIV infection
    • Sharpstone D, Gazzard B: Gastrointestinal manifestations of HIV infection. Lancet 1996, 348:379-383.
    • (1996) Lancet , vol.348 , pp. 379-383
    • Sharpstone, D.1    Gazzard, B.2
  • 2
    • 0025942043 scopus 로고
    • Lymphoid organs function as major reservoir for human immunodeficiency virus
    • Pantaleo G, Graziosi C, Butini L, et al.: Lymphoid organs function as major reservoir for human immunodeficiency virus. Proc Natl Acad Sci USA 1991, 88:9838-9842.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 9838-9842
    • Pantaleo, G.1    Graziosi, C.2    Butini, L.3
  • 3
    • 0027538456 scopus 로고
    • HIV infection is active and progressive in lymphoid tissues during clinically latent stage of disease
    • Pantaleo G, Graziosi C, Demarest JF, et al.: HIV infection is active and progressive in lymphoid tissues during clinically latent stage of disease. Nature 1993, 362:355-358.
    • (1993) Nature , vol.362 , pp. 355-358
    • Pantaleo, G.1    Graziosi, C.2    Demarest, J.F.3
  • 4
    • 0027516822 scopus 로고
    • Massive covert infection of helper T lymphoycytes and macrophages by HIV during the incubation period of AIDS
    • Embretson J, Zupanic M, Ribas JL, et al.: Massive covert infection of helper T lymphoycytes and macrophages by HIV during the incubation period of AIDS. Nature 1993, 362:359-362.
    • (1993) Nature , vol.362 , pp. 359-362
    • Embretson, J.1    Zupanic, M.2    Ribas, J.L.3
  • 5
    • 0025949779 scopus 로고
    • Detection, localization, and quantitation of HIV-associated antigens in intestinal biopsies from patients with HIV
    • Kotler DP, Reka S, Borcich A, Cronin WJ: Detection, localization, and quantitation of HIV-associated antigens in intestinal biopsies from patients with HIV. Am J Pathol 1991, 139:823-830.
    • (1991) Am J Pathol , vol.139 , pp. 823-830
    • Kotler, D.P.1    Reka, S.2    Borcich, A.3    Cronin, W.J.4
  • 6
    • 0028811367 scopus 로고
    • Loss of CD4 lymphocytes in patients infected with human immunodeficiency virus type 1 is more pronounced in the duodenal mucosa than in the peripheral blood
    • Schneider T, Jahn HU, Schmidt W, et al.: Loss of CD4 lymphocytes in patients infected with human immunodeficiency virus type 1 is more pronounced in the duodenal mucosa than in the peripheral blood. Gut 1995, 37:524-529.
    • (1995) Gut , vol.37 , pp. 524-529
    • Schneider, T.1    Jahn, H.U.2    Schmidt, W.3
  • 7
    • 0013470173 scopus 로고    scopus 로고
    • Mucosal HIV infection: A paradigm for dysregulation of the mucosal immune system
    • Edited by MF Kagnoff, Kiyono H. San Diego: Academic Press
    • Zeitz M, Schneider T, Ullrich R: Mucosal HIV infection: a paradigm for dysregulation of the mucosal immune system. In Essentials of Mucosal Immunology. Edited by MF Kagnoff, Kiyono H. San Diego: Academic Press; 1997:421-436.
    • (1997) Essentials of Mucosal Immunology , pp. 421-436
    • Zeitz, M.1    Schneider, T.2    Ullrich, R.3
  • 8
    • 0024791277 scopus 로고
    • An efficient salt-chloroform extraction of DNA from blood and tissues
    • Mühlenbach R, Lagoda PJ, Welter C: An efficient salt-chloroform extraction of DNA from blood and tissues. Trends Genet 1989, 5:391.
    • (1989) Trends Genet , vol.5 , pp. 391
    • Mühlenbach, R.1    Lagoda, P.J.2    Welter, C.3
  • 9
    • 0027284889 scopus 로고
    • Human endogenous retroviral element K10 (HERV-K10) encodes a full length Gag 73 kDa protein and a functional protease
    • Mueller-Lantzsch N, Sauter M, Weiskircher A, et al.: Human endogenous retroviral element K10 (HERV-K10) encodes a full length Gag 73 kDa protein and a functional protease. AIDS Res Hum Retroviruses 1993, 9:343-350.
    • (1993) AIDS Res Hum Retroviruses , vol.9 , pp. 343-350
    • Mueller-Lantzsch, N.1    Sauter, M.2    Weiskircher, A.3
  • 11
    • 0029089406 scopus 로고
    • Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys
    • Du Z, Lang SM, Sasseville VG, et al.: Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys. Cell 1995, 82:665-674.
    • (1995) Cell , vol.82 , pp. 665-674
    • Du, Z.1    Lang, S.M.2    Sasseville, V.G.3
  • 13
    • 0028853962 scopus 로고    scopus 로고
    • Functional characterization of human immunodeficiency virus type 1 nef genes in patients with divergent rates of disease progression
    • Michael NL, Chang G, d'Arcy LA, Tseng CJ, Birx DL, Sheppard HW: Functional characterization of human immunodeficiency virus type 1 nef genes in patients with divergent rates of disease progression. J Virol 69:6758-6769.
    • J Virol , vol.69 , pp. 6758-6769
    • Michael, N.L.1    Chang, G.2    D'Arcy, L.A.3    Tseng, C.J.4    Birx, D.L.5    Sheppard, H.W.6
  • 14
    • 0029846223 scopus 로고    scopus 로고
    • High frequency of defective nef alleles in a long-term survivor with non progressive human immunodeficiency virus type 1 infection
    • Mariani R, Kirchhoff F, Greenough TC, Sullivan JL, Desrosiers RC, Skowronski J: High frequency of defective nef alleles in a long-term survivor with non progressive human immunodeficiency virus type 1 infection. J Virol 70:7752-7764.
    • J Virol , vol.70 , pp. 7752-7764
    • Mariani, R.1    Kirchhoff, F.2    Greenough, T.C.3    Sullivan, J.L.4    Desrosiers, R.C.5    Skowronski, J.6
  • 17
    • 0026493503 scopus 로고
    • Expression and localization of the Nef protein from human immunodeficiency virus-1 in stably transfected B-cells
    • Kienzle N, Bachmann M, Müller WE, Mueller-Lantzsch N: Expression and localization of the Nef protein from human immunodeficiency virus-1 in stably transfected B-cells. Arch Virol 1992, 124:123-132.
    • (1992) Arch Virol , vol.124 , pp. 123-132
    • Kienzle, N.1    Bachmann, M.2    Müller, W.E.3    Mueller-Lantzsch, N.4
  • 18
    • 0021717961 scopus 로고
    • Molecular chararcterization of human T-cell leukemia (lymphotropic) virus type III in the acquired immune deficiency syndrome
    • Shaw GM, Hahn BH, Arya SK, Groopman JE, Gallo RC, Wong-Staal F: Molecular chararcterization of human T-cell leukemia (lymphotropic) virus type III in the acquired immune deficiency syndrome. Science 1984, 226: 1165-1171.
    • (1984) Science , vol.226 , pp. 1165-1171
    • Shaw, G.M.1    Hahn, B.H.2    Arya, S.K.3    Groopman, J.E.4    Gallo, R.C.5    Wong-Staal, F.6
  • 19
    • 0028835788 scopus 로고
    • Brief report: Absence of intact nef sequences in a long-term survivor with non-progressive HIV-1 infection
    • Kirchhoff F, Greenough TC, Brettler DB, Sullivan JL. Desrosiers RC: Brief report: absence of intact nef sequences in a long-term survivor with non-progressive HIV-1 infection. N Engl J Med 1995, 332:228-232.
    • (1995) N Engl J Med , vol.332 , pp. 228-232
    • Kirchhoff, F.1    Greenough, T.C.2    Brettler, D.B.3    Sullivan, J.L.4    Desrosiers, R.C.5
  • 20
    • 0028804160 scopus 로고    scopus 로고
    • Genomic structure of an attenuated quasispecies of HIV-1 from a blood transfusion donor and recipients
    • Deacon NJ, Tsykin A, Solomon A, et al.: Genomic structure of an attenuated quasispecies of HIV-1 from a blood transfusion donor and recipients. Science 1996, 270:988-991.
    • (1996) Science , vol.270 , pp. 988-991
    • Deacon, N.J.1    Tsykin, A.2    Solomon, A.3
  • 21
    • 0028879189 scopus 로고
    • Potential applications of proviral load measurement in clinical retrovirology
    • Conway B, Monpetit M, Raboud J, et al.: Potential applications of proviral load measurement in clinical retrovirology. J Acquir Immune Defic Syndr 1995, 10 (suppl 2):S45-S50.
    • (1995) J Acquir Immune Defic Syndr , vol.10 , Issue.2 SUPPL.
    • Conway, B.1    Monpetit, M.2    Raboud, J.3
  • 22
    • 0002243359 scopus 로고
    • Characteristics and functions of mucosa-associated lymphoid tissue
    • Edited by Ogra PL, Mesterchy J, Lamm ME, Strober W, McGhee JR, Bienenstock J. San Diego: Academic Press
    • Croitorun K, Bienenstock J: Characteristics and functions of mucosa-associated lymphoid tissue. In Handbook of Mucosal Immunology. Edited by Ogra PL, Mesterchy J, Lamm ME, Strober W, McGhee JR, Bienenstock J. San Diego: Academic Press; 1994:141-149
    • (1994) Handbook of Mucosal Immunology , pp. 141-149
    • Croitorun, K.1    Bienenstock, J.2
  • 23
    • 0027941411 scopus 로고
    • Quantitative analysis of mononuclear cells expressing human immunodeficiency virus type 1 RNA in esophageal mucosa
    • Smith PD, Fox CH, Masur H, Winter HS, Alling DW: Quantitative analysis of mononuclear cells expressing human immunodeficiency virus type 1 RNA in esophageal mucosa. J Exp Med 1994, 180:1541-1546.
    • (1994) J Exp Med , vol.180 , pp. 1541-1546
    • Smith, P.D.1    Fox, C.H.2    Masur, H.3    Winter, H.S.4    Alling, D.W.5
  • 25
    • 0029016740 scopus 로고
    • Decreased human immunodeficiency virus type 1 plasma viremia during antiretroviral therapy reflects downregulation of viral replication in lymphoid tissue
    • Cohen OJ, Pantaleo G, Holodniy M, et al.: Decreased human immunodeficiency virus type 1 plasma viremia during antiretroviral therapy reflects downregulation of viral replication in lymphoid tissue. Proc Natl Acad Sci USA 1995, 92:6017-6021.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6017-6021
    • Cohen, O.J.1    Pantaleo, G.2    Holodniy, M.3
  • 26
    • 0023176085 scopus 로고
    • An inducible transcription factor activates expression of human immunodeficiency virus in T cells
    • Nabel G, Baltimore D: An inducible transcription factor activates expression of human immunodeficiency virus in T cells Nature 1987, 326:711-713.
    • (1987) Nature , vol.326 , pp. 711-713
    • Nabel, G.1    Baltimore, D.2
  • 27
    • 0023871935 scopus 로고
    • Lymphocytes isolated from the intestinal lamia propria of normal non-human primates have increased expression of genes associated with T-cell activation
    • Zeitz M, Greene WC, Peffer NJ, James SP: Lymphocytes isolated from the intestinal lamia propria of normal non-human primates have increased expression of genes associated with T-cell activation. Gastroenterology 1988, 94:647-655.
    • (1988) Gastroenterology , vol.94 , pp. 647-655
    • Zeitz, M.1    Greene, W.C.2    Peffer, N.J.3    James, S.P.4
  • 28
    • 0028650308 scopus 로고
    • Cell differentiation and proliferation in the gastrointestinal tract with respect to the local immune system
    • Zeitz M, Ullrich R, Schneider T, Schieferdecker HL, Riecken EO: Cell differentiation and proliferation in the gastrointestinal tract with respect to the local immune system. Ann NY Acad Sci 1994, 733:75-86.
    • (1994) Ann NY Acad Sci , vol.733 , pp. 75-86
    • Zeitz, M.1    Ullrich, R.2    Schneider, T.3    Schieferdecker, H.L.4    Riecken, E.O.5
  • 29
    • 0025277210 scopus 로고
    • Lipopolysaccharide is a potent monocyte/macrophage-specific stimulator of human immunodeficiency virus type 1 expression
    • Pomerantz RJ, Feinberg MB, Trono O, Baltimore D: Lipopolysaccharide is a potent monocyte/macrophage-specific stimulator of human immunodeficiency virus type 1 expression. J Exp Med 1990, 172:253-261.
    • (1990) J Exp Med , vol.172 , pp. 253-261
    • Pomerantz, R.J.1    Feinberg, M.B.2    Trono, O.3    Baltimore, D.4
  • 30
    • 0026642177 scopus 로고
    • CD14 is involved in control of human immunodeficiency virus type 1 expression in latently infected cells by lipopolysaccharide
    • Bagasra O, Wright SD, Seshamma T, Oakes JW, Pomerantz RJ: CD14 is involved in control of human immunodeficiency virus type 1 expression in latently infected cells by lipopolysaccharide. Proc Natl Acad Sci USA 1992, 89:6285-6289.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6285-6289
    • Bagasra, O.1    Wright, S.D.2    Seshamma, T.3    Oakes, J.W.4    Pomerantz, R.J.5
  • 31
    • 0025012838 scopus 로고
    • Tumor necrosis factor-α functions in an autocrine manner in the induction of human immunodeficiency virus expression
    • Poli G, Kinter A, Justement JS, et al.: Tumor necrosis factor-α functions in an autocrine manner in the induction of human immunodeficiency virus expression Proc Natl Acad Sci USA 1990, 87:782.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 782
    • Poli, G.1    Kinter, A.2    Justement, J.S.3
  • 32
    • 0026588510 scopus 로고
    • Human cytomegalovirus-stimulated peripheral blood mononulear cells induce HIV-1 replication via a tumor necrosis factor-α-mediated mechanism
    • Peterson PK, Gekker G, Chao CC, et al.: Human cytomegalovirus-stimulated peripheral blood mononulear cells induce HIV-1 replication via a tumor necrosis factor-α-mediated mechanism J Clin Invest 1992, 89:574-580.
    • (1992) J Clin Invest , vol.89 , pp. 574-580
    • Peterson, P.K.1    Gekker, G.2    Chao, C.C.3
  • 33
    • 0025160079 scopus 로고
    • Preferential infection of CD4+ memory T-cells by human immunodeficiency virus type 1: Evidence for a role in the selective T-cell functional defects observed in infected individuals
    • Schnittman SM, Lane HC, Greenhouse J, Justment JS, Baseler M, Fauci AS: Preferential infection of CD4+ memory T-cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals. Proc Natl Acad Sci USA 1990, 87:6058-6062.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6058-6062
    • Schnittman, S.M.1    Lane, H.C.2    Greenhouse, J.3    Justment, J.S.4    Baseler, M.5    Fauci, A.S.6
  • 34
    • 0025052645 scopus 로고
    • Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persisitent human immunodeficiency virus type 1 infection of CEM cells
    • Pauza CD, Galindo JE, Richman DD: Reinfection results in accumulation of unintegrated viral DNA in cytopathic and persisitent human immunodeficiency virus type 1 infection of CEM cells. J Exp Med 1990, 172:1035-1042.
    • (1990) J Exp Med , vol.172 , pp. 1035-1042
    • Pauza, C.D.1    Galindo, J.E.2    Richman, D.D.3
  • 35
    • 0027743583 scopus 로고
    • HIV-1 infection in the lymphoid organs
    • Graziosi C, Pantaleo G, Demarest JF, et al.: HIV-1 infection in the lymphoid organs. AIDS 1993, 7 (suppl 2):S53-S58.
    • (1993) AIDS , vol.7 , Issue.2 SUPPL.
    • Graziosi, C.1    Pantaleo, G.2    Demarest, J.F.3
  • 36
    • 0029773395 scopus 로고    scopus 로고
    • Viral load and immunophenotype of cells obtained from lymph nodes by fine needle aspiration as compared with peripheral blood cells in HIV-infected patients
    • Meylan RRA, Bügisser P, Weyrich-Suter C, Spertini F: Viral load and immunophenotype of cells obtained from lymph nodes by fine needle aspiration as compared with peripheral blood cells in HIV-infected patients. J Acquir Immune Defic Syndr 1996, 13:39-47.
    • (1996) J Acquir Immune Defic Syndr , vol.13 , pp. 39-47
    • Meylan, R.R.A.1    Bügisser, P.2    Weyrich-Suter, C.3    Spertini, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.