메뉴 건너뛰기




Volumn 32, Issue 12, 1996, Pages 2155-2163

Human antibodies against the polymorphic epithelial mucin in ovarian cancer patients recognise a novel sequence in the tandem repeat region

Author keywords

epitope mapping; human antibodies; immune response; polymorphic epithelial mucin; tumour associated antigens

Indexed keywords

EPITOPE; MUCIN; POLYMORPHIC EPITHELIAL MUCIN; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 0030298428     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(96)00254-7     Document Type: Article
Times cited : (21)

References (40)
  • 2
    • 0027595079 scopus 로고
    • Identifying strategies for immune intervention
    • 2. Lanzavecchia A. Identifying strategies for immune intervention. Science 1994, 260, 937-944.
    • (1994) Science , vol.260 , pp. 937-944
    • Lanzavecchia, A.1
  • 3
    • 0025029968 scopus 로고
    • Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin
    • 3. Gendler SJ, Lancaster CA, Taylor-Papadimitriou J, et al. Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin. J Biol Chem 1990, 265, 15286-15293.
    • (1990) J Biol Chem , vol.265 , pp. 15286-15293
    • Gendler, S.J.1    Lancaster, C.A.2    Taylor-Papadimitriou, J.3
  • 4
    • 0024353046 scopus 로고
    • A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas
    • 4. Girling A, Bartkova J, Burchell J, Gendler S, Gillett C, Taylor-Papadimitriou J. A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas. Int J Cancer 1989, 43, 1072-1076.
    • (1989) Int J Cancer , vol.43 , pp. 1072-1076
    • Girling, A.1    Bartkova, J.2    Burchell, J.3    Gendler, S.4    Gillett, C.5    Taylor-Papadimitriou, J.6
  • 5
    • 0023741252 scopus 로고
    • A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats
    • 5. Gendler SJ, Taylor-Papadimitriou J, Duhig T, Rothbard J, Burchell J. A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats. J Biol Chem 1988, 263, 12820-12823.
    • (1988) J Biol Chem , vol.263 , pp. 12820-12823
    • Gendler, S.J.1    Taylor-Papadimitriou, J.2    Duhig, T.3    Rothbard, J.4    Burchell, J.5
  • 6
    • 0023617395 scopus 로고
    • Development and characterisation of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin
    • 6. Burchell J, Gendler S, Taylor-Papadimitriou J, et al. Development and characterisation of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin. Cancer Res 1987, 47, 5476-5482.
    • (1987) Cancer Res , vol.47 , pp. 5476-5482
    • Burchell, J.1    Gendler, S.2    Taylor-Papadimitriou, J.3
  • 7
    • 0025916187 scopus 로고
    • Expression of the gene coding for a human mucin in mouse mammary tumor cells can affect their tumorigenicity
    • 7. Lalani EN, Berdichevsky F, Boshell M, et al. Expression of the gene coding for a human mucin in mouse mammary tumor cells can affect their tumorigenicity. J Biol Chem 1991, 266, 15420-15426.
    • (1991) J Biol Chem , vol.266 , pp. 15420-15426
    • Lalani, E.N.1    Berdichevsky, F.2    Boshell, M.3
  • 8
    • 0026629044 scopus 로고
    • Second generation anti-MUC1 peptide monoclonal antibodies
    • 8. Xing PX, Prenzoska J, Quelch K, McKenzie IFC. Second generation anti-MUC1 peptide monoclonal antibodies. Cancer Res 1992, 52, 2310-2317.
    • (1992) Cancer Res , vol.52 , pp. 2310-2317
    • Xing, P.X.1    Prenzoska, J.2    Quelch, K.3    McKenzie, I.F.C.4
  • 9
    • 0027234998 scopus 로고
    • Immunogenicity of synthetic peptides related to the core peptide sequence encoded by the human MUC-1 mucin gene: Effect of immunization on the growth of murine mammary adenocarcinoma cells transfected with the human MUC-1 gene
    • 9. Ding L, Lalani EN, Reddish M, et al. Immunogenicity of synthetic peptides related to the core peptide sequence encoded by the human MUC-1 mucin gene: effect of immunization on the growth of murine mammary adenocarcinoma cells transfected with the human MUC-1 gene. Cancer Immun Immunother 1993, 36, 9-17.
    • (1993) Cancer Immun Immunother , vol.36 , pp. 9-17
    • Ding, L.1    Lalani, E.N.2    Reddish, M.3
  • 10
    • 0027195386 scopus 로고
    • Human B-cell immune response to the polymorphic epithelial mucin
    • 10. Rughetti A, Turchi V, Apollonj Ghetti C, et al. Human B-cell immune response to the polymorphic epithelial mucin. Cancer Res 1993, 53, 2457-2459.
    • (1993) Cancer Res , vol.53 , pp. 2457-2459
    • Rughetti, A.1    Turchi, V.2    Apollonj Ghetti, C.3
  • 11
    • 0028235908 scopus 로고
    • Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic and colon cancer patients
    • 11. Kotera Y, Fontenot JD, Pecher G, Metzgar RS, Finn OJ. Humoral immunity against a tandem repeat epitope of human mucin MUC-1 in sera from breast, pancreatic and colon cancer patients. Cancer Res 1994, 54, 2856-2860.
    • (1994) Cancer Res , vol.54 , pp. 2856-2860
    • Kotera, Y.1    Fontenot, J.D.2    Pecher, G.3    Metzgar, R.S.4    Finn, O.J.5
  • 12
    • 0028840265 scopus 로고
    • Polymorphic epithelial mucin (MUC-1)-containing circulating immune complexes in carcinoma patients
    • 12. Gourevitch MM, Mensdorff-Pouilly SV, Litvinov SV, et al. Polymorphic epithelial mucin (MUC-1)-containing circulating immune complexes in carcinoma patients. Br J Cancer 1995, 72, 934-938.
    • (1995) Br J Cancer , vol.72 , pp. 934-938
    • Gourevitch, M.M.1    Mensdorff-Pouilly, S.V.2    Litvinov, S.V.3
  • 13
    • 0030017992 scopus 로고    scopus 로고
    • Humoral immune response to polymorphic epithelial mucin (MUC-1) in patients with benign and malignant breast tumours
    • 13. Von Mensdorff-Pouilly S, Gourevitch MM, Kenemans P, et al. Humoral immune response to polymorphic epithelial mucin (MUC-1) in patients with benign and malignant breast tumours. Eur J Cancer 1996, 32A, 1325-1331.
    • (1996) Eur J Cancer , vol.32 A , pp. 1325-1331
    • Von Mensdorff-Pouilly, S.1    Gourevitch, M.M.2    Kenemans, P.3
  • 14
    • 0024454148 scopus 로고
    • Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells
    • 14. Band LD, Lan MS, Metzgar RS, Finn OJ. Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells. Proc Natl Acad Sci USA 1989, 86, 7159-7163.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 7159-7163
    • Band, L.D.1    Lan, M.S.2    Metzgar, R.S.3    Finn, O.J.4
  • 15
    • 0025834851 scopus 로고
    • Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells
    • 15. Jerome KR, Barnd DL, Bendt KM, et al. Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells. Cancer Res 1991, 51, 2908-2916.
    • (1991) Cancer Res , vol.51 , pp. 2908-2916
    • Jerome, K.R.1    Barnd, D.L.2    Bendt, K.M.3
  • 16
    • 0027383267 scopus 로고
    • Biophysical of one-, two-, and three-tandem repeats of human mucin (MUC-1) protein core
    • 16. Fontenot JD, Tjandra N, Bu D, Ho C, Montelaro RC, Finn OJ. Biophysical of one-, two-, and three-tandem repeats of human mucin (MUC-1) protein core. Cancer Res 1993, 53, 5386-5394.
    • (1993) Cancer Res , vol.53 , pp. 5386-5394
    • Fontenot, J.D.1    Tjandra, N.2    Bu, D.3    Ho, C.4    Montelaro, R.C.5    Finn, O.J.6
  • 18
    • 0019426220 scopus 로고
    • Monoclonal antibodies to epithelium specific components of the human milk fat globule membrane: Production and reaction with cells in culture
    • 18. Taylor-Papadimitriou J, Peterson JA, Arklie J, Burchell J, Ceriani RL, Bodmer WF. Monoclonal antibodies to epithelium specific components of the human milk fat globule membrane: production and reaction with cells in culture. Int J Cancer 1981, 28, 17-21.
    • (1981) Int J Cancer , vol.28 , pp. 17-21
    • Taylor-Papadimitriou, J.1    Peterson, J.A.2    Arklie, J.3    Burchell, J.4    Ceriani, R.L.5    Bodmer, W.F.6
  • 19
    • 0026689696 scopus 로고
    • Characterisation of monoclonal antibody 436 recognising the ARG-PRO-ALA-PRO sequence of the polymorphic epithelial mucin (PEM) protein core in breast carcinoma cells
    • 19. Nuti M, Turchi V, Rughetti A, et al. Characterisation of monoclonal antibody 436 recognising the ARG-PRO-ALA-PRO sequence of the polymorphic epithelial mucin (PEM) protein core in breast carcinoma cells. Int J Biol Markers 1992, 7, 71-79.
    • (1992) Int J Biol Markers , vol.7 , pp. 71-79
    • Nuti, M.1    Turchi, V.2    Rughetti, A.3
  • 22
    • 0027484287 scopus 로고
    • Effect of modification of carbohydrate side chains on the reactivity of antibodies with core-protein epitopes of the MUC-1 gene product
    • 22. Burchell J, Taylor-Papadimitriou J. Effect of modification of carbohydrate side chains on the reactivity of antibodies with core-protein epitopes of the MUC-1 gene product. Epith Cell Biol 1993, 2, 155-162.
    • (1993) Epith Cell Biol , vol.2 , pp. 155-162
    • Burchell, J.1    Taylor-Papadimitriou, J.2
  • 23
    • 0024795060 scopus 로고
    • Inhibition of mucin glycosylation by aryl-N-acetyl-alpha-galactosaminides in human colon cancer cells
    • 23. Kuan SF, Byrd JC, Kim YS. Inhibition of mucin glycosylation by aryl-N-acetyl-alpha-galactosaminides in human colon cancer cells. J Biol Chem 1989, 264, 19271-19277.
    • (1989) J Biol Chem , vol.264 , pp. 19271-19277
    • Kuan, S.F.1    Byrd, J.C.2    Kim, Y.S.3
  • 24
    • 0027431402 scopus 로고
    • Tumor immunity as autoimmunity: Tumor antigens include normal self proteins which stimulate anergic peripheral T cells
    • 24. Parmiani G. Tumor immunity as autoimmunity: tumor antigens include normal self proteins which stimulate anergic peripheral T cells. Immunol Today 1993, 14, 536-538.
    • (1993) Immunol Today , vol.14 , pp. 536-538
    • Parmiani, G.1
  • 25
    • 43949158638 scopus 로고
    • Can anti-tumor immune responses discriminate between self and nonself?
    • 25. Moudgil KD, Sercarz EE. Can anti-tumor immune responses discriminate between self and nonself? Immunol Today 1994, 15, 353-355.
    • (1994) Immunol Today , vol.15 , pp. 353-355
    • Moudgil, K.D.1    Sercarz, E.E.2
  • 26
    • 0029055849 scopus 로고
    • Induction of anti-self-immunity to cure cancer
    • 26. Nanda NK, Sercarz EE. Induction of anti-self-immunity to cure cancer. Cell 1995, 82, 13-17.
    • (1995) Cell , vol.82 , pp. 13-17
    • Nanda, N.K.1    Sercarz, E.E.2
  • 27
    • 0024450187 scopus 로고
    • A short sequence, within the tandem repeat of a cancer-associated mucin, contains immunodominant epitopes
    • 27. Burchell J, Taylor-Papadimitriou J, Boshell M, Gendler S, Duhig T. A short sequence, within the tandem repeat of a cancer-associated mucin, contains immunodominant epitopes. Int J Cancer 1989, 44, 691-696.
    • (1989) Int J Cancer , vol.44 , pp. 691-696
    • Burchell, J.1    Taylor-Papadimitriou, J.2    Boshell, M.3    Gendler, S.4    Duhig, T.5
  • 28
    • 0027930505 scopus 로고
    • N-acetylgalactosamine glycosylation of MUC1 tandem repeat peptides by pancreatic tumor cell extracts
    • 28. Nishimori I, Perini F, Mountjoy KP, et al. N-acetylgalactosamine glycosylation of MUC1 tandem repeat peptides by pancreatic tumor cell extracts. Cancer Res 1994, 54, 3738-3744.
    • (1994) Cancer Res , vol.54 , pp. 3738-3744
    • Nishimori, I.1    Perini, F.2    Mountjoy, K.P.3
  • 29
    • 0028963728 scopus 로고
    • Studies on the order and site specificity of Ga1NAc transfer to MUC1 tandem repeats by UDP-Ga1NAc: Polypeptide N-acetyl-galactosaminyltransferase from milk or mammary carcinoma cells
    • 29. Stadie TR, Chai W, Lawson AM, Byfield PG, Hanish FG. Studies on the order and site specificity of Ga1NAc transfer to MUC1 tandem repeats by UDP-Ga1NAc: polypeptide N-acetyl-galactosaminyltransferase from milk or mammary carcinoma cells. Eur J Biochem 1995, 229, 140-147.
    • (1995) Eur J Biochem , vol.229 , pp. 140-147
    • Stadie, T.R.1    Chai, W.2    Lawson, A.M.3    Byfield, P.G.4    Hanish, F.G.5
  • 30
    • 0027146671 scopus 로고
    • Antibody response against the c-erbB-2 oncoprotein in breast carcinoma patients
    • 30. Pupa SM, Ménard S, Andreola S, Colnaghi MI. Antibody response against the c-erbB-2 oncoprotein in breast carcinoma patients. Cancer Res 1993, 53, 5864-5866.
    • (1993) Cancer Res , vol.53 , pp. 5864-5866
    • Pupa, S.M.1    Ménard, S.2    Andreola, S.3    Colnaghi, M.I.4
  • 31
    • 0028144438 scopus 로고
    • Existent T-cell and antibody immunity to HER-2/neu protein in patients with breast cancer
    • 31. Disis ML, Calenoff E, McLaughlin G, et al. Existent T-cell and antibody immunity to HER-2/neu protein in patients with breast cancer. Cancer Res 1994, 54, 16-20.
    • (1994) Cancer Res , vol.54 , pp. 16-20
    • Disis, M.L.1    Calenoff, E.2    McLaughlin, G.3
  • 33
    • 0028986986 scopus 로고
    • Expression of monoclonal-antibody-denned antigens in fractions isolated from human breast carcinomas and patients' serum
    • 33. Croce MV, Price MR, Segal-Eiras AE. Expression of monoclonal-antibody-denned antigens in fractions isolated from human breast carcinomas and patients' serum . Cancer Immun Immunother 1995, 40, 132-137.
    • (1995) Cancer Immun Immunother , vol.40 , pp. 132-137
    • Croce, M.V.1    Price, M.R.2    Segal-Eiras, A.E.3
  • 34
    • 0027136829 scopus 로고
    • Analysis of p53 antibodies in patients with various cancers define B-cell epitopes of human p53: Distribution on primary structure and exposure on protein surface
    • 34. Lubin R, Schlichtholz B, Bengoufa D, et al. Analysis of p53 antibodies in patients with various cancers define B-cell epitopes of human p53: distribution on primary structure and exposure on protein surface. Cancer Res 1993, 53, 5872-5876.
    • (1993) Cancer Res , vol.53 , pp. 5872-5876
    • Lubin, R.1    Schlichtholz, B.2    Bengoufa, D.3
  • 35
    • 0026674937 scopus 로고
    • Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation
    • 35. Winter SF, Minna JD, Johnson BE, Takahashi T, Gazdar AF, Carbone DP. Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation. Cancer Res 1992, 52, 4168-4174.
    • (1992) Cancer Res , vol.52 , pp. 4168-4174
    • Winter, S.F.1    Minna, J.D.2    Johnson, B.E.3    Takahashi, T.4    Gazdar, A.F.5    Carbone, D.P.6
  • 36
    • 0025744449 scopus 로고
    • Does antibody-dependent epitope masking permit progressive tumor growth in the face of cell-mediated cytotoxicity?
    • 36. Manson LA. Does antibody-dependent epitope masking permit progressive tumor growth in the face of cell-mediated cytotoxicity? Immunol Today 1991, 12, 352-355.
    • (1991) Immunol Today , vol.12 , pp. 352-355
    • Manson, L.A.1
  • 37
    • 0021956416 scopus 로고
    • Antigen-specific interaction between T and B cells
    • 37. Lanzavecchia A. Antigen-specific interaction between T and B cells. Nature 1985, 314, 537-539.
    • (1985) Nature , vol.314 , pp. 537-539
    • Lanzavecchia, A.1
  • 38
    • 0024320379 scopus 로고
    • Epitope-directed processing of specific antigen by B lymphocytes
    • 38. Davidson HW, Watts C. Epitope-directed processing of specific antigen by B lymphocytes. J Cell Biol 1989, 109, 85-92.
    • (1989) J Cell Biol , vol.109 , pp. 85-92
    • Davidson, H.W.1    Watts, C.2
  • 39
    • 0029035307 scopus 로고
    • Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants
    • 39. Simitsek PD, Campbell DG, Lanzavecchia A, Fairweather N, Watts C. Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants. J Exp Med 1995, 181, 1957-1963.
    • (1995) J Exp Med , vol.181 , pp. 1957-1963
    • Simitsek, P.D.1    Campbell, D.G.2    Lanzavecchia, A.3    Fairweather, N.4    Watts, C.5
  • 40
    • 0028875822 scopus 로고
    • Identification of an HLA-A11-restricted epitope from the tandem repeat domain of the epithelial tumor antigen mucin
    • 40. Domenech N, Henderson RA, Finn OJ. Identification of an HLA-A11-restricted epitope from the tandem repeat domain of the epithelial tumor antigen mucin. J Immunol 1995, 155, 4766-4774.
    • (1995) J Immunol , vol.155 , pp. 4766-4774
    • Domenech, N.1    Henderson, R.A.2    Finn, O.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.