Promotion by mixtures of dichloroacetic acid and trichloroacetic acid of N-methyl-N-nitrosourea-initiated cancer in the liver of female B6C3F1 mice

Cancer Letters

Volumn 115, Issue 1, 1997, Pages 15-23

  Pereira, Michael A ^a   Li, Kewa ^a   Kramer, Paula M ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Dichloroacetic acid; Liver carcinogenesis; Mixtures; Trichloroacetic acid; Tumor promotion

Indexed keywords

DICHLOROACETIC ACID; GLUTATHIONE TRANSFERASE; METHYLNITROSOUREA; TRICHLOROACETIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASOPHIL; CELL PROLIFERATION; CONTROLLED STUDY; EOSINOPHIL; FEMALE; LIVER CARCINOGENESIS; LIVER CELL; LIVER TUMOR; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; TUMOR PROMOTION;

ANIMALS; BODY WEIGHT; CARCINOGENS; COCARCINOGENESIS; DICHLOROACETATE; DRUG COMBINATIONS; FEMALE; GLUTATHIONE TRANSFERASE; IMMUNOHISTOCHEMISTRY; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; METHYLNITROSOUREA; MICE; ORGAN SIZE; TIME FACTORS; TRICHLOROACETIC ACID; WATER POLLUTANTS, CHEMICAL;

ANIMALIA;

EID: 0031148563     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)04699-5     Document Type: Article

References (37)

1. [1] Uden, P.C. and Miller, J.W. (1983) Chlorinated acids and chloral in drinking water, J. Am. Water Works Assoc., 75, 524-527.
2. [2] Krasner, S.W., McGuire, M.J., Jacangelo, J.G., Patania, N.L., Reagen, K.M. and Ajeta, E.M. (1989) The occurrence of disinfection by-products in U.S. drinking water, J. Am. Water Works Assoc., 81, 41-53.
3. [3] Miller, J.W. and Uden, P.C. (1983) Characterization of non-volatile aqueous chlorination products of humic substances, Environ. Sci. Technol., 17, 150-157.
4. [4] Coleman, E.W., Munch, J.W., Kaylor, W.H., Streicher, R.P., Ringhand, H.P. and Meier, J.R. (1984) Gas chromatography/mass spectroscopy analysis of mutagenic extracts of aqueous chlorinated humic acid. A comparison of the byproducts to drinking water contaminants, Environ. Sci. Technol., 18, 674-678.
5. [5] International Agency for Research on Cancer (1979) Trichloroethylene. In: IARC Monograph on the Evaluation of the Carcinogenic Risk of Chemicals to Human. Vol. 20, pp. 545-788. IARC, Lyon, France.
6. [6] Dekant, W., Metzler, M. and Henschler, D. (1984) Novel metabolites of trichloroethylene through dechlorination reactions in mice and humans, Biochem. Pharmacol., 33, 2021-2027.
7. [7] Bruckner, J.V., Davis, B.D. and Blancato, J.N. (1989) Metabolism, toxicity, and carcinogenicity of trichloroethylene, CRC Crit. Rev. Toxicol., 20, 31-50.
8. [8] Elcombe, C.R. (1985) Species differences in carcinogenicity and peroxisome proliferation due to trichloroethylene: a biochemical human hazard assessment, Arch. Toxicol. Suppl., 8, 6-17.
9. [9] Elcombe, C.R., Rose, M.S. and Pratt, I.S. (1985) Biochemical, histological, and ultrastructural changes in rat and mouse liver following the administration of trichloroethylene: possible relevance to species differences in hepatocarcinogenicity, Toxicol. Appl. Pharmacol., 79, 365-376.
10. [10] Goldsworthy, T.L. and Popp, J.A. (1987) Chlorinated hydrocarbon-induced peroxisomal enzyme activity in relation to species and organ carcinogenicity, Toxicol. Appl. Pharmacol., 88, 225-233.
11. [11] Odum, J., Green, T., Foster, J.R. and Hext, P.M. (1988) The role of trichloroacetic acid and peroxisome proliferation in the differences in carcinogenicity of perchloroethylene in the mouse and rat, Toxicol. Appl. Pharmacol., 92, 103-112.
12. [12] Bull, R.J., Sanchez, I.M., Nelson, M.A., Larson, J.L. and Lansing, A.J. (1990) Liver tumor induction in B6C3F1 mice by dichloroacetate and trichloroacetate, Toxicology, 63, 341-359.
13. [13] Pereira, M.A. (1996) Carcinogenic activity of dichloroacetic acid and trichloroacetic acid in the liver of female B6C3F1 mice, Fundam. Appl. Toxicol., 31, 192-199.
14. [14] Herren-Freund, S.L., Pereira, M.A., Khoury, M.D. and Olson, G. (1987) The carcinogenicity of trichloroethylene and its metabolites, trichloroacetic and dichloroacetic acid, in mouse liver, Toxicol. Appl. Pharmacol., 90, 183-189.
15. [15] DeAngelo, A.B., Daniel, F.B., Stober, L.A. and Olson, G.R. (1991) The carcinogenicity of dichloroacetic acid in the male B6C3F1 mouse, Fundam. Appl. Toxicol., 16, 337-347.
16. [16] Anna, C.H., Maronpot, R.R., Pereira, M.A., Foley, J.F., Malarkey, D.E. and Anderson, M.W. (1994) Ras proto-oncogene activation in dichloroacetic acid-, trichloroethylene- and tetrachloroethylene-induced liver tumors in B6C3F1 mice, Carcinogenesis, 15, 2255-2261.
17. [17] Pereira, M.A. and Phelps, J.B. (1996) Promotion by dichloroacetic acid and trichloroacetic acid of methylnitrosurea-induced cancer in the liver of female B6C3F1 mice, Cancer Lett., 102, 133-141.
18. [18] National Cancer Institute (1976) Carcinogenesis Bioassay of Trichloroethylene, CAS No. 79-01-6 NCI-CG-TR-2. NCI, Washington, DC.
19. [19] National Toxicology Program (1983) Carcinogenesis Bioassay of Trichloroethylene (Without Epichlorohydrin) in F344/N rats and B6C3F1/N mice (Gavage Studies), Tech. Rep. 243, NIH Publ. No. 83-1799. US Department of Health and Human Services, Washington, DC.
20. [20] National Toxicology Program (1988) Toxicology and Carcinogenesis Studies of Trichloroethylen in Four Strains of Rats (ACI, August, Marshell, Osborne-Mendel), NTP TR 273, NIH Publ. No. 88-2529. US Department of Health and Human Services, Bethesda, MD.
21. [21] National Toxicology Program (1990) Carcinogenesis Studies of Trichloroethylene in F344/N Rats and B6C3F1 Mice, NTP Technical Report No. 243. US Department of Health and Human Services, Bethesda, MD.
22. [22] Fukuda, K., Takemoto, K. and Tsuruta, H. (1983) Inhalation carcinogenicity of trichloroethylene in mice and rats, Ind. Health., 21, 243-252.
23. [23] Rapson, W.H., Nazar, M.A. and Butsky, V.V. (1980) Mutagenicity produced by aqueous chlorination of organic compounds, Bull. Environ. Contam. Toxicol., 24, 590-597.
24. [24] Herbert, V., Gardner, A. and Coleman, N. (1980) Mutagenicity of dichloroacetate, an ingredient of some formulations of pangamic acid (tradename 'vitamin B15'), Am. J. Clin. Nutr., 33, 1179-1182.
25. [25] Chang, L.W., Daniel, F.B. and DeAngelo, A.B. (1992) Analysis of DNA strand breaks induced in rodent liver in vivo, hepatocytes in primary culture, and a human cell line by chlorinated acetic acids and chlorinated acetaldehydes, Environ. Mol. Mutagenesis, 20, 277-288.
26. [26] Fox, A.W., Yang, X., Murli, H., Lawlor, T.E., Cifone, M.A. and Reno, F.E. (1996) Absence of mutagenic effects of sodium dichloroacetate, Fundam. Appl. Toxicol., 32, 87-95.
27. [27] Ferreira-Gonzalez, A., DeAngelo, A.B., Nasim, S. and Garrett, C.T. (1995) Ras oncogene activation during hepatocarcinogenesis in B6C3F1 male mice by dichloroacetic and trichloroacetic acids, Carcinogenesis, 16, 495-500.
28. [28] Moody, D.E., Reddy, J.K., Lake, B.C., Poop, J.A. and Reese, D.H. (1991) Peroxisome proliferation and nongenotoxic carcinogenesis: commentary on a symposium, Fundam. Appl. Toxicol., 16, 233-248.
29. [29] Reddy, J.K. and Rao, M.S. (1992) Peroxisome proliferation and hepatocarcinogenesis, IARC Sci. Publ., 116, 225-235.
30. [30] Goodman, J.I., Ward, J.M., Popp, J.A., Klauning, J.E. and Fox, T.R. (1991) Mouse liver Carcinogenesis: mechanisms and relevance, Fundam. Appl. Toxicol., 17, 651-665.
31. [31] Ward, J.M., Rice, J.M., Creasia, D., Lynch, P. and Riggs, C. (1983) Dissimilar patterns of promotion by di(2-ethylhexyl)phthalate and phenobarbital of hepatocellular neoplasia initiated by diethylnitrosamine in B6C3F1 mice, Carcinogenesis, 4, 1021-1029.
32. [32] Dragani, T.A., Manenti, G., Galliani, G. and Della Porta, G. (1985) Promoting effects of 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene in mouse hepatocarcinogenesis, Carcinogenesis, 6, 225-228.
33. [33] Weghorst, C.M. and Klaunig, J.E. (1989) Phenobarbital promotion in diethylnitrosamine-initiated infant B6C3F1 mice: influence of gender, Carcinogenesis, 10, 609-612.
34. [34] Hatayama, I., Nishimura, S., Narita, T. and Sato, K. (1993) Sex-dependent expression of class pi glutathione S-transferase during chemical hepatocarcinogenesis in BC3F1 mice, Carcinogenesis, 14, 537-538.
35. [35] Diwan, B.A., Lubet, R.A., Ward, J.M., Hrabie, J.A. and Rice, J.M. (1992) Tumor-promoting and hepatocarcinogenic effects of 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP) in DBA/2NCr and C57BL/6NO mice and an apparent promoting effect on nasal cavity tumors but not on hepatocellular tumors in F344/NCr rats initiated with N-nitronitrosodiethelamine, Carcinogenesis, 13, 1893-1901.
36. [36] Marsman, D.S. and Popp, J.A. (1994) Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, Wy-14,643, Carcinogenesis, 15, 111-117.
37. [37] Dunnett, C.W. (1955) A multiple comparison procedure for comparing several treatments with a control, J. Am. Stat. Assoc., 50, 1096-1121.