CD1d on myeloid dendritic cells stimulates cytokine secretion from and cytolytic activity of Vα24JαQ T cells: A feedback mechanism for immune regulation

Journal of Immunology

Volumn 165, Issue 7, 2000, Pages 3756-3762

  Yang, O O ^a   Racke, F K ^a   Phuong Thi Nguyen, ^a   Gausling, R ^a   Severino, M E ^a   Horton, H F ^a   Byrne, M C ^a   Strominger, J L ^a   Brian Wilson, S ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD1 ANTIGEN; CYTOKINE; INTERLEUKIN 12; INTERLEUKIN 4; MONOCLONAL ANTIBODY;

ANTIGEN EXPRESSION; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOLYSIS; DENDRITIC CELL; FEEDBACK SYSTEM; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREGULATION; LYMPHOCYTE CLONE; LYMPHOCYTE DIFFERENTIATION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0034292330     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.7.3756     Document Type: Article

References (57)

1. Isolation and characterization of a cDNA and gene coding for a fourth CD1 molecule
2. CD1d-restricted and TCR-mediated activation of vα14 NKT cells by glycoceramides
3. Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove
4. Binding and antigen presentation of ceramide-containing glycolipids by soluble mouse and human CD1d molecules
5. Mouse CD1-specific NK1 T cells: Development, specificity, and function
6. Overexpression of natural killer T cells protects Vα14-Jα281 transgenic nonobese diabetic mice against diabetes
7. - T-cell deficiency and IDDM in NOD/Lt mice
8. - (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10
9. Extreme Th 1 bias of invariant Vα24JαQ T cells in type I diabetes
10. + T cell IL-4 production is revealed in IL-4 receptor-deficient mice
11. A defect in interleukin 12-induced activation and interferon-γ secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes
12. CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4
13. Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells
14. Murine natural killer cells contribute to the granulomatous reaction caused by mycobacterial cell walls
15. + cells as effectors of IFN-γ dependent immunity to Toxoplasma gondii in MHC class I-deficient mice
16. + effector function against intracellular infection
17. Involvement of decidual Vα14 NKT cells in abortion
18. CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site
19. Requirement for Vα14 NKT cells in IL-12-mediated rejection of tumors
20. Cutting edge: Inhibition of experimental tumor metastasis by dendritic cells pulsed with α-galactosylceramide
21. Differential tumor surveillance by natural killer (NK) and NKT cells
22. The natural killer (NKT) cell ligand α-galactosylceramide demonstrates its immunopotentiating effect by inducing interleukin (IL)-12 production by dendritic cells and IL-12 receptor expression on NKT cells
23. +NKT cells: Atimulation of IL-12 production by antigen-presenting cells in the innate immune system
24. The CD1 system: Antigen-presenting molecules for T cell recognition of lipids and glycolipids
25. CD1d structure and regulation on human thymocytes, peripheral blood T cells, B cells and monocytes
26. Multiple differences in gene expression in regulatory Vα24JαQ T cells from identical twins discordant for type I diabetes
27. Dendritic cells and the control of immunity
28. - T cells
29. Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium
30. Association of PI 3-kinase with a specific motifin the T cell receptor ζ chain upon T cell activation
31. CD161 (NKR-P1A) costimulation of CD1d-dependent activation of human T cells expressing invariant Vα24JαQ T cell receptor a chains
32. Chemokines and the homing of dendritic cells to the T cell areas of lymphoid organs
33. Improved method for the generation of dendritic cells from nonproliferating progenitors in human blood
34. Mobilizing dendritic cells for tolerance, priming, and chronic inflammation
35. Protective immunity induced by tumor vaccines requires interaction between CD40 and its ligand CD154
36. + T cells
37. CD137 induces proliferation and endomitosis in monocytes
38. The CTL's kiss of death
39. CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells
40. β chemokines are released from HIV-1-specific cytolytic T cell granules complexed to proteoglycans
41. Human dendritic cells and macrophages: In situ immunophenotypic definition of subsets that exhibit morphologic and microenvironmental characteristics
42. Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells
43. + natural killer T-cell cytotoxic activity: An important immune regulatory function
44. - subclasses of dendritic cells direct the development of distinct T helper cells in vivo
45. Reciprocal control of T helper cell and dendritic cell differentiation
46. The control of T cell responses by dendritic cell subsets
47. Triggering of natural killer cells by the costimulatory molecule CD80 (rfpag B7-10
48. Dendritic cells directly trigger NK cell functions: Cross-talk relevant in innate anti-tumor immune responses in vivo
49. Recognition of autologous dendritic cells by human NK cells
50. Targeting of human dendritic cells by autologous NK cells
51. Cutting edge: Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells
52. Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue
53. Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes
54. Inherited human caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II
55. +-like thymocytes in the NOD mouse
56. + NK T cells associated with disease development in autoimmune-prone mice
57. Selective reduction of T cells bearing invariant Vα24JαQ antigen receptor in patients with systemic sclerosis