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An authoritative and thorough review of the several facets of DCs
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Banchereau J., Steinman R.M. Dendritic cells and the control of immunity. Nature. 392:1998;245-252. An authoritative and thorough review of the several facets of DCs.
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Banchereau, J.1
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Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: Downregulation by cytokines and bacterial products
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Sallusto F., Cella M., Danieli C., Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med. 182:1995;389-400.
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6
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Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes
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5 integrin and cross-presentation on MHC class I molecules
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5 integrin and cross-presentation on MHC class I molecules.
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Cyster, J.G.1
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Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells
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Macatonia S.E., Hosken N.A., Litton M., Vieira P., Hsieh C.S., Culpepper J.A., Wysocka M., Trinchieri G., Murphy K.M., O'Garra A. Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J Immunol. 154:1995;5071-5079.
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10
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0029812593
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Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
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Cella M., Scheidegger D., Palmer-Lehmann K., Lane P., Lanzavecchia A., Alber G. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Med. 184:1996;747-752.
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Cella, M.1
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11
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High level IL-12 production by murine dendritic cells: Upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10
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Koch F., Stanzl U., Jennewein P., Janke K., Heufler C., Kampgen E., Romani N., Schuler G. High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10. J Exp Med. 184:1996;741-746.
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12
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0030963666
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Human dendritic cells require exogenous interleukin-12-inducing factors to direct the development of naive T-helper cells toward the Th1 phenotype
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Hilkens C.M., Kalinski P., de Boer M., Kapsenberg M.L. Human dendritic cells require exogenous interleukin-12-inducing factors to direct the development of naive T-helper cells toward the Th1 phenotype. Blood. 90:1997;1920-1926.
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Hilkens, C.M.1
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13
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0031814098
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Th1 cells induce and Th2 inhibit antigen dependent IL-12 secretion by dendritic cells
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Antigen-specific Th1 cells induce the production of IL-12 from DCs, whereas IL-10 produced by Th2 cells can prevent IL-12 secretion
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Ria F., Penna G., Adorini L. Th1 cells induce and Th2 inhibit antigen dependent IL-12 secretion by dendritic cells. Eur J Immunol. 28:1998;2003-2016. Antigen-specific Th1 cells induce the production of IL-12 from DCs, whereas IL-10 produced by Th2 cells can prevent IL-12 secretion.
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Ria, F.1
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14
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0033370612
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Relative efficiency of microglia, astrocytes, dendritic cells and B cells in naive CD4+ T cell priming and Th1/Th2 cell restimulation
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+ T cells. Microglia functionally resemble DCs, except for an inferior capacity to prime naïve T cells
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+ T cells. Microglia functionally resemble DCs, except for an inferior capacity to prime naïve T cells.
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Aloisi, F.1
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15
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Dendritic cells: Unique leukocyte populations which control the primary immune response
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Hart D.N. Dendritic cells: unique leukocyte populations which control the primary immune response. Blood. 90:1997;3245-3287.
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Hart, D.N.1
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16
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0026481133
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Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
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Inaba K., Inaba M., Romani N., Aya H., Deguchi M., Ikehara S., Muramatsu S., Steinman R.M. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med. 176:1992;1693-1702.
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Inaba, K.1
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17
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0031570952
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Dendritic cell subtypes in mouse lymphoid organs: Cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes
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Vremec D., Shortman K. Dendritic cell subtypes in mouse lymphoid organs: cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes. J Immunol. 159:1997;565-573.
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Vremec, D.1
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18
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2642714927
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Heterogeneity of mouse spleen dendritic cells: In vivo phagocytic activity, expression of macrophage markers, and subpopulation turnover
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This paper (with [17]) describes DC subsets from mouse secondary lymphoid organs, with a fairly comprehensive description of their phenotype
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Leenen P.J., Radosevic K., Voerman J.S., Salomon B., van Rooijen N., Klatzmann D., van Ewijk W. Heterogeneity of mouse spleen dendritic cells: in vivo phagocytic activity, expression of macrophage markers, and subpopulation turnover. J Immunol. 160:1998;2166-2173. This paper (with [17]) describes DC subsets from mouse secondary lymphoid organs, with a fairly comprehensive description of their phenotype.
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Leenen, P.J.1
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19
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0031225999
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Developmental pathways of dendritic cells in vivo: Distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice
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Pulendran B., Lingappa J., Kennedy M.K., Smith J., Teepe M., Rudensky A., Maliszewski C.R., Maraskovsky E. Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice. J Immunol. 159:1997;2222-2231.
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Pulendran, B.1
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Maliszewski, C.R.7
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20
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0028949219
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Mouse thymus dendritic cells: Kinetics of development and changes in surface markers during maturation
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Wu L., Vremec D., Ardavin C., Winkel K., Suss G., Georgiou H., Maraskovsky E., Cook W., Shortman K. Mouse thymus dendritic cells: kinetics of development and changes in surface markers during maturation. Eur J Immunol. 25:1995;418-425.
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21
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0030456366
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Dendritic cell development in culture from thymic precursor cells in the absence of granulocyte/macrophage colony-stimulating factor
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Saunders D., Lucas K., Ismaili J., Wu L., Maraskovsky E., Dunn A., Shortman K. Dendritic cell development in culture from thymic precursor cells in the absence of granulocyte/macrophage colony-stimulating factor. J Exp Med. 184:1996;2185-2196.
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Saunders, D.1
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22
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0033068180
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- subclasses of dendritic cells direct the development of distinct T helper cells in vivo
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+ DCs
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+ DCs.
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Maldonado-López, R.1
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Moser, M.10
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23
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0033514364
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Distinct dendritic cell subsets differentially regulate the class of immune response in vivo
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- DCs inducing Th2 responses in vivo. Experiments were also performed using Flt-3L and GM-CSF-treated mice, which preferentially expand the lymphoid and myeloid populations, respectively. Additionally, the humoral response was measured, demonstrating that LDCs and MDCs are able to generate Th1- and Th2-type antibody responses
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- DCs inducing Th2 responses in vivo. Experiments were also performed using Flt-3L and GM-CSF-treated mice, which preferentially expand the lymphoid and myeloid populations, respectively. Additionally, the humoral response was measured, demonstrating that LDCs and MDCs are able to generate Th1- and Th2-type antibody responses.
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Proc Natl Acad Sci USA
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Pulendran, B.1
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Maliszewski, C.R.7
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24
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0033074360
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Antigen-pulsed CD8alpha+ dendritic cells generate an immune response after subcutaneous injection without homing to the draining lymph node
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+ DCs did not travel to the draining lymph node following injection into the hind footpad, but were still able to prime T cells
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+ DCs did not travel to the draining lymph node following injection into the hind footpad, but were still able to prime T cells.
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Smith, A.L.1
Fazekas De St Groth, B.2
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25
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0030852624
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Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells
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Kurts C., Kosaka H., Carbone F.R., Miller J.F., Heath W.R. Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells. J Exp Med. 186:1997;239-245.
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Kurts, C.1
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Heath, W.R.5
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26
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0029920922
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A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis
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Suss G., Shortman K. A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis. J Exp Med. 183:1996;1789-1796.
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Suss, G.1
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27
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0032189552
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The evolution of self-tolerance: A new cell arises to meet the challenge of self-reactivity
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Fazekas de St Groth B. The evolution of self-tolerance: a new cell arises to meet the challenge of self-reactivity. Immunol Today. 19:1998;448-454.
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Fazekas De St Groth, B.1
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28
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0031798137
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Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells
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The authors demonstrate that mouse, immature dendritic cells phagocytose both necrotic and apoptotic human and mouse B cell blasts, and present MHC derived peptides
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Inaba K., Turley S., Yamaide F., Iyoda T., Mahnke K., Inaba M., Pack M., Subklewe M., Sauter B., Sheff D.et al. Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells. J Exp Med. 188:1998;2163-2173. The authors demonstrate that mouse, immature dendritic cells phagocytose both necrotic and apoptotic human and mouse B cell blasts, and present MHC derived peptides.
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Inaba, K.1
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29
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0029812040
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Constitutive class I-restricted exogenous presentation of self antigens in vivo
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Kurts C., Heath W.R., Carbone F.R., Allison J., Miller J.F., Kosaka H. Constitutive class I-restricted exogenous presentation of self antigens in vivo. J Exp Med. 184:1996;923-930.
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Kurts, C.1
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30
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0344527868
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Functional skewing of bone marrow-derived dendritic cells by Th1- Or Th2-inducing cytokines
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Sato M., Iwakabe K., Kimura S., Nishimura T. Functional skewing of bone marrow-derived dendritic cells by Th1- or Th2-inducing cytokines. Immunol Lett. 67:1999;63-68.
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Sato, M.1
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31
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0000060327
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In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas
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Sousa C.R., Hieny S., Scharton-Kersten T., Jankovic D., Charest H., Germain R.N., Sher A. In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas. J Exp Med. 186:1997;1819-1829.
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Sousa, C.R.1
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Sher, A.7
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32
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0033591630
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Interleukin 12-dependent interferon gamma production by CD8alpha+ lymphoid dendritic cells
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LDCs from RAG-2-deficient, natural-killer-cell-depleted mice produce IFN-γ
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Ohteki T., Fukao T., Suzue K., Maki C., Ito M., Nakamura M., Koyasu S. Interleukin 12-dependent interferon gamma production by CD8alpha+ lymphoid dendritic cells. J Exp Med. 189:1999;1981-1986. LDCs from RAG-2-deficient, natural-killer-cell-depleted mice produce IFN-γ.
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Ohteki, T.1
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33
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0032479869
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Activated murine B lymphocytes and dendritic cells produce a novel CC chemokine which acts selectively on activated T cells
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+ blasts
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+ blasts.
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Schaniel, C.1
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34
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0033120969
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The CC chemokine receptor-7 ligands 6Ckine and macrophage inflammatory protein-3 beta are potent chemoattractants for in vitro- And in vivo-derived dendritic cells
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Kellermann S.A., Hudak S., Oldham E.R., Liu Y.J., McEvoy L.M. The CC chemokine receptor-7 ligands 6Ckine and macrophage inflammatory protein-3 beta are potent chemoattractants for in vitro- and in vivo-derived dendritic cells. J Immunol. 162:1999;3859-3864.
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Kellermann, S.A.1
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35
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10144260007
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CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha
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Caux C., Vanbervliet B., Massacrier C., Dezutter-Dambuyant C., de Saint-Vis B., Jacquet C., Yoneda K., Imamura S., Schmitt D., Banchereau J. CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha. J Exp Med. 184:1996;695-706.
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Caux, C.1
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36
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0028285230
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Proliferating dendritic cell progenitors in human blood
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Romani N., Gruner S., Brang D., Kampgen E., Lenz A., Trockenbacher B., Konwalinka G., Fritsch P.O., Steinman R.M., Schuler G. Proliferating dendritic cell progenitors in human blood. J Exp Med. 180:1994;83-93.
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37
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0029961746
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CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells
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Zhou L.J., Tedder T.F. CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells. Proc Natl Acad Sci USA. 93:1996;2588-2592.
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Zhou, L.J.1
Tedder, T.F.2
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38
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0033103128
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Maturation, activation, and protection of dendritic cells induced by double-stranded RNA
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This work describes the maturation of DCs by influenza virus and double-stranded RNA, their production of type I interferons and the expression of MxA, which protects against the cytopathic effects of viral infection
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Cella M., Salio M., Sakakibara Y., Langen H., Julkunen I., Lanzavecchia A. Maturation, activation, and protection of dendritic cells induced by double-stranded RNA. J Exp Med. 189:1999;821-829. This work describes the maturation of DCs by influenza virus and double-stranded RNA, their production of type I interferons and the expression of MxA, which protects against the cytopathic effects of viral infection.
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J Exp Med
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Cella, M.1
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39
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0033168630
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Polyriboinosinic polyribocytidylic acid (poly[I:C]) induces stable maturation of functionally active human dendritic cells
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Poly(I:C) can lead to the maturation of DCs, increasing their co-stimulatory molecule expression, production of IL-12 and the capacity to induce strong alloresponses
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Verdijk R.M., Mutis T., Esendam B., Kamp J., Melief C.J., Brand A., Goulmy E. Polyriboinosinic polyribocytidylic acid (poly[I:C]) induces stable maturation of functionally active human dendritic cells. J Immunol. 163:1999;57-61. Poly(I:C) can lead to the maturation of DCs, increasing their co-stimulatory molecule expression, production of IL-12 and the capacity to induce strong alloresponses.
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Verdijk, R.M.1
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40
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0033135451
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Coordinated events during bacteria-induced DC maturation
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Rescigno M., Granucci F., Citterio S., Foti M., Ricciardi-Castagnoli P. Coordinated events during bacteria-induced DC maturation. Immunol Today. 20:1999;200-203.
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Rescigno, M.1
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41
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Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures
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Winzler C., Rovere P., Rescigno M., Granucci F., Penna G., Adorini L., Zimmermann V.S., Davoust J., Ricciardi-Castagnoli P. Maturation stages of mouse dendritic cells in growth factor-dependent long-term cultures. J Exp Med. 185:1997;317-328.
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