A defect in interleukin 12-induced activation and interferon γ secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes mellitus

Journal of Experimental Medicine

Volumn 190, Issue 7, 1999, Pages 963-972

  Falcone, Marika ^a   Yeung, Brian ^a   Tucker, Lee ^a   Rodriguez, Enrique ^a   Sarvetnick, Nora ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Autoimmunity; Interferon ; Interleukin 4; Natural killer T cells; Regulatory cells

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4; T LYMPHOCYTE RECEPTOR;

AGE; ANIMAL CELL; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DIABETOGENESIS; IMMUNOMODULATION; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SPLEEN CELL; STRAIN DIFFERENCE; T LYMPHOCYTE ACTIVATION; THYMOCYTE;

ANIMALS; AUTOIMMUNITY; CELL DIFFERENTIATION; DIABETES MELLITUS, TYPE 1; INFLAMMATION; INTERFERON TYPE II; INTERLEUKIN-12; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, SCID; PHENOTYPE; RECEPTORS, ANTIGEN, T-CELL; TH2 CELLS;

EID: 0033523666     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.190.7.963     Document Type: Article

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