Enhanced pulmonary allergic responses to Aspergillus in CCR2(-/-) mice

Journal of Immunology

Volumn 165, Issue 5, 2000, Pages 2603-2611

  Blease, K ^a   Mehrad, B ^a   Standiford, T J ^a   Lukacs, N W ^a   Gosling, J ^a   Boring, L ^a   Charo, I F ^a   Kunkel, S L ^a   Hogaboam, C M ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; CHEMOKINE; EOTAXIN; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 5; RANTES; SPASMOGEN;

ALLERGIC REACTION; ARTICLE; ASPERGILLUS FUMIGATUS; ASTHMA; CONTROLLED STUDY; CYSTIC FIBROSIS; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; INFLAMMATION; LUNG LAVAGE; MOUSE; NONHUMAN; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL;

EID: 0034283964     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.5.2603     Document Type: Article

References (41)

1. Review of fungus-induced asthmatic reactions
2. Clinical and serological survey of pulmonary aspergillosis in patients with cystic fibrosis
3. Increased antigen-specific Th-2 response in allergic bronchopulmonary aspergillosis (ABPA) in patients with cystic fibrosis
4. J Allergy Clin. Immunol.
5. Allergic bronchopulmonary aspergillosis: Model of bronchopulmonary disease with defined serologic, radiologic, pathologic and clinical findings from asthma to fatal destructive lung disease
6. Chemokines and their role in human disease
7. Role of CCR5 and CCR2 polymorphisms in HIV-1 transmission and disease progression
8. Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1
9. Role of CCR5 in organ-specific and innate immunity to Cryptococcus neoformans
10. Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
11. Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor
12. Chronic inflammation upregulates chemokine receptors and induces neutrophil migration to monocyte chemoattractant protein-1
13. Chemokine-leukocyte interactions: The voodoo that they do so well
14. Chronic airway hyperreactivity, goblet cell hyperplasia, and peribronchial fibrosis during allergic airway disease induced by Aspergillus fumigatus
15. Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice
16. Immunomodulatory role of C10 chemokine in a murine model of allergic bronchopulmonary aspergillosis
17. A sensitive ELISA for the detection of human monocyte chemoattractant protein-1 (MCP-I)
18. Neutralization of the CXC chemokine, macrophage inflammatory protein-2, attenuates bleomycin-induced pulmonary fibrosis
19. IgE down regulation and cytokine induction by Aspergillus antigens in human allergic bronchopulmonary aspergillosis
20. Allergic bronchopulmonary aspergillosis
21. Selective protection against conidia by mononuclear and against mycelia by polymorphonuclear phagocytes in resistance to Aspergillus: Observations on these two lines of defense in vivo and in vitro with human and mouse phagocytes
22. Role of TNFα in pulmonary host defense in murine invasive aspergillosis
23. Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
24. IL-5-dependent conversion of normodense human eosinophils to the hypodense phenotype uses 3T3 fibroblasts for enhanced viability, accelerated hypodensity, and sustained antibody-dependent cytotoxicity
25. Requirement for IL-13 independently of IL-4 in experimental asthma
26. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
27. Coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness
28. Mouse monocyte-derived chemokine is involved in airway hyperreactivity and lung inflammation
29. Animal models of asthma and chronic bronchitis
30. Pulmonary aspergillosis: A survey of its occurrence in patients with chronic lung disease and a discussion of the significance of diagnostic tests
31. Allergic bronchopulmonary aspergillosis in cystic fibrosis
32. Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice
33. Aspergillosis and lung defenses
34. Inhibition of lymphocyte adhesion to cytokine-activated synovial fibroblasts by glucocorticoids involves the attenuation of vascular cell adhesion molecule I and intercellular adhesion molecule 1 gene expression
35. Activated T cells and cytokines in bronchoalveolar lavages from patients with various lung diseases associated with eosinophilia
36. Aspergillus fumigatus antigen exposure results in pulmonary airway resistance in wild-type but not in IL-4 knockout mice
37. Aspergillus fumigatus antigen induced eosinophilia in mice is abrogated by anti-IL-5 antibody
38. Immunopathologic responses to Aspergillus antigen in interleukin-4 knockout mice
39. Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergiltosis
40. Tumor necrosis factor-α and interteukln-1 α expression in a murine model of allergic bronchopulmonary aspergillosis
41. STCP-1 (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13