Animal models of asthma and chronic bronchitis

Clinical and Experimental Allergy, Supplement

Volumn 29, Issue 2, 1999, Pages 37-47

  Drazen, J M ^a,b   Takebayashi, T ^b   Long, N C ^b   De Sanctis, G T ^a   Shore, S A ^b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Capsaicin; Linkage analysis; Mice; Neuropeptides

Indexed keywords

CAPSAICIN; NEUROPEPTIDE; SULFUR DIOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ASTHMA; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; BRONCHUS MUCUS; CHRONIC BRONCHITIS; CONFERENCE PAPER; CONTROLLED STUDY; GENETIC LINKAGE; GENOME; MOUSE; NERVE FIBER C; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

ANIMALS; ASTHMA; BRONCHITIS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; MICE; RATS;

EID: 0032973829     PISSN: 09602178     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (76)

1. Douglas JS, Ridgway P, Brink C. Airway responses of the guinea pig in vivo and in vitro. J Pharmacol Exp Ther 1977; 202:116-24.
2. Snapper JR, Drazen JM, Loring SH, Schneider W, Ingram RH Jr. Distribution of pulmonary responsiveness to aerosol histamine in dogs. J Appl Physiol 1978; 44:738-42.
3. Levitt RC, Mitzner W. Expression of airway hyperreactivity to acetylcholine as a simple autosomal recessive trait in mice. FASEB J 1988; 2:2605-8.
4. Levitt RC, Mitzner W. Autosomal recessive inheritance of airway hyperreactivity to 5-hydroxytryptamine. J Appl Physiol 1989; 67:1125-32.
5. National Asthma Education Program. Guidelines for the diagnosis and management of asthma. Bethesda, Maryland: U.S. Department of Health and Human Services, 1991.
6. Cockcroft DW, Berscheid BA, Murdock KY. Unimodal distribution of bronchial responsiveness to inhaled histamine in a random human population. Chest 1983; 83:751-4.
7. Townley RG, Bewtra A, Wilson AF et al. Segregation analysis of bronchial response to methacholine inhalation challenge in families with and without asthma. J Allergy Clin Immunol 1986; 77:101-7.
8. Hopp RJ, Bewtra AK, Biven R, Nair NM, Townley RG. Bronchial reactivity pattern in nonasthmatic parents of asthmatics. Ann Allergy 1988; 61:184-6.
9. Lang DM, Hopp RJ, Bewtra AK et al. Distribution of methacholine inhalation challenge responses in a selected adult population. J Allergy Clin Immunol 1987; 79:533-40.
10. Longo G, Strinati R, Poli F, Fumi F. Genetic factors in nonspecific bronchial hyperreactivity. An epidemiologic study. Am J Dis Child 1987; 141:331-4.
11. Cockcroft DW, Hargreave FE. Airway hyperresponsiveness. Relevance of random population data to clinical usefulness. Am Rev Respir Dis 1990; 142:497-500.
12. Hopp RJ, Townley RG, Biven RE, Bewtra AK, Nair NM. The presence of airway reactivity before the development of asthma. Am Rev Respir Dis 1990; 141:2-8.
13. 20 determination in a random selection of young college students. J Allergy Clin Immunol 1992; 89:23-30.
14. Palmeiro EM, Hopp RJ, Biven RE et al. Probability of asthma based on methacholine challenge. Chest 1992; 101:630-3.
15. Ando A, Martin TR, Galli SJ. Effects of chronic treatment with the c-kit ligand, stem cell factor, on immunoglobulin-E dependent anaphylaxis in mice - Genetically mast cell deficient SI/SI (d) mice acquire anaphylactic responsiveness, but the congenic normal mice do not exhibit augmented responses. J Clin Invest 1993; 92:1639-49.
16. Oettgen HC, Martin TR, Wynshaw-Boris A et al. Active anaphylaxis in IgE-deficient mice. Nature 1994; 370:367-70.
17. Mehlhop PD, Vanderijn M, Goldberg AB et al. Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma. Proc Natl Acad Sci USA 1997; 94:1344-9.
18. Larsen GL, Renz H, Loader JE, Bradley KL, Gelfand EW. Airway response to electrical field stimulation in sensitized inbred mice. Passive transfer of increased responsiveness with peribronchial lymph nodes. J Clin Invest 1992; 89:747-52.
19. Renz H, Smith HR, Henson JE et al. Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse. J Allergy Clin Immunol 1992; 89:1127-38.
20. Hamelmann E, Vella AT, Oshiha A et al. Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice. Proc Natl Acad Sci USA 1997; 94:1350-5.
21. Hamelmann E, Oshiha A, Loader J et al. Anti-interleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization. Am J Respir Crit Care Med 1997; 155:819-25.
22. Hamelmann E, Oshiba A, Schwarze J et al. Allergen-specific IgE and IL-5 are essential for the development of airway hyperresponsiveness. Am J Respir Cell Molec Biol 1997; 16:674-82.
23. Takeda K, Hamelmann E, Joetham A et al. Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice. J Exp Med 1997; 186:449-54.
24. Corry DB, Folkesson HG, Warnock ML et al. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med 1996; 183:109-17.
25. Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J Exp Med 1996; 183:195-201.
26. Eum SY, Creminon C, Haile S, Lefort J, Vargaftig BB. Inhibition of airways inflammation by dexamethasone is followed by reduced bronchial hyperreactivity in BP2 mice. Clin Exp Allergy 1996; 26:971-9.
27. Konno S, Adachi M, Matsuura T et al. Bronchial reactivity to methacholine and serotonin in six inred mouse strains. Arerugi 1993; 42:42-7.
28. Ewart SL, Mitzner W, Disilvestre DA, Meyers DA, Levitt RC. Airway hyperresponsiveness to acetylcholine: segregation analysis and evidence for linkage to murine chromosome 6. Am J Respir Cell Molec Biol 1996; 14:487-95.
29. Nicolaides NC, Holroyd KJ, Ewart SL et al. Interleukin 9: a candidate gene for asthma. Proc Natl Acad Sci USA 1997; 94:13175-80.
30. De Sanctis GT, Merchant M, Beier DR et al. Quantitative locus anal airway hyperresponsiveness a/JC57BL/6J mice. Nat Genet 1995; 11:150-4.
31. Lander ES, Green P, Abrahamson J et al. MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics 1987; 1:174-81.
32. Dietrich W, Katz H, Lincoln SE et al. A genetic map of the mouse suitable for typing intraspecific crosses. Genet 1992; 131:423-47.
33. Martin TR, Gerard NP, Galli SJ, Drazen JM. Pulmonary responses to bronchoconstrictor agonists in the mouse. J Appl Physiol 1988; 64:2318-23.
34. Lander ES, Kruglyak L. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results. Nature Genet 1995; 11:241-7.
35. Man SF, Hulbert WC, Man G, Mok K, Williams DJ. Effects of SO2 exposure on canine pulmonary epithelial functions. Exp Lung Res 1989; 15:181-98.
36. 2 inhalation: an in vivo and in vitro study. Scanning Microscopy 1989; 3:369-78.
37. 2 induction of chronic bronchitis. Am Rev Respir Dis 1994; 147 (Suppl.):A72 (abstract).
38. Lamb D, Reid L. Mitotic rates, goblet cell increase and histochemical changes in mucus in rat bronchial epithelium during exposure to sulphur dioxide. J Pathol Bacteriol 1968; 96:97-111.
39. Miller ML, Andringa A, Rafales L, Vinegar A. Effect of exposure to 500 ppm sulfur dioxide on the lungs of the ferret. Respiration 1985; 48:346-54.
40. Vai F, Fournier MF, Lafuma JC, Touaty F, Pariente R. SO2-induced bronchopathy in the rat: abnormal permeability of the bronchial epithelium in vivo and in vitro after anatomic recovery. Am Rev Respir Dis 1980; 121:851-8.
41. Reid LM. An experimental study of hypersecretion of mucus in the bronchial tree. Br J Exp Path 1963; 44:437-45.
42. Shore S, Kobzik L, Long NC et al. Increased airway responsiveness to inhaled methacholine in a rat model of chronic bronchitis. Am J Respir Crit Care Med 1995; 151:1931-8.
43. Jany B, Gallup M, Tsuda T, Basbaum C. Mucin gene expression in rat airways following infection and irritation. Biochem Biophys Res Commun 1991; 181:1-8.
44. Knauss HJ, Medici TC, Chodosh S, Robinson WE. Cell vs. noncell airway temporal response in rats exposed to sulfur dioxide. Arch Environ Health 1976; 31:241-7.
45. Lightowler NM, Williams JR. Tracheal mucus flow rates in experimental bronchitis in rats. Br J Exp Pathol 1969; 50:139-49.
46. Broillet A, White R, Ventrone R, Giessinger N. Efficacy of fenspiride in alleviating SO2 induced chronic bronchitis in rats and allergic rhinitis in guinea pigs. Rhinol 1988; 4 (Suppl.):75-83.
47. Clark JN, Dalbey WE, Stephenson KB. Effect of sulfur dioxide on the morphology and mucin biosynthesis by the rat trachea. J Environ Pathol Toxicol 1980; 4:197-207.
48. Chakrin LW, Saunders LZ. Experimental chronic bronchitis. Pathol Dog Lab Invest 1974; 30:145-54.
49. Pon DJ, van Staden CJ, Rodger IW. Hypertrophic and hyperplastic changes of mucus-secreting epithelial cells in rat airways: assessment using a novel, rapid, and simple technique. Am J Respir Cell Mol Biol 1994; 10:625-34.
50. Bhaskar KR, Drazen JM, O'Sullivan DD, Scanlon PM, Reid LM. Transition from normal to hypersecretory bronchial mucus in a canine model of bronchitis: changes in yield and composition. Exp Lung Res 1988; 14:101-20.
51. Koshino T, Bhaskar KR, Reid LM et al. Recovery of an epitope recognized by a novel monoclonal antibody from airway lavage during experimental induction of chronic bronchitis. Am J Respir Cell Mol Biol 1990; 2:453-62.
52. Litt M, Khan MA, Chakrin LW, Sosnowski G, Wardell JR Jr Effect of chronic sulfur dioxide inhalation on rheological properties of tracheal mucus. Biorheol 1976; 13:107-14.
53. Sommerhoff CP, Nadel JA, Basbaum CB, Caughey GH. Neutrophil elastase and cathepsin G stimulate secretion from cultured bovine airway gland serous cells. J Clin Invest 1990; 85:682-9.
54. Breuer R, Christensen TG, Lucey EC et al. Elastase causes secretory discharge in bronchi of hamsters with clastase-induced secretory cell metaplasia. Exp Lung Res 1993; 19:273-82.
55. Farone A, Huang S, Paulauskis J, Kobzik L, Airway neutrophilia and chemokine mRNA expression in sulfur dioxide-induced bronchitis. Am J Respir Cell Mol Biol 1995; 12:345-50.
56. Dalhamm T, Strandberg L. Acute effect of sulfur dioxide on the rate of ciliary beat in the trachea of rabbit, in vivo and in vitro, with studies on the absorptional capacity of the nasal cavity. Int J Air Poll Water Poll 1961; 4:154-67.
57. Frank NR, Yoder RE, Brain JD, Yokoyama E. SO2 (35S labeled) absorption by the nose and mouth under conditions of varying concentration and flow. Arch Environ Health 1969; 18:315-22.
58. Shore SA, Kariya ST, Anderson K et al. Sulfur-dioxide-induced bronchitis in dogs. Effects on airway responsiveness to inhaled and intravenously administered methacholine. Am Rev Respir Dis 1987; 135:840-7.
59. Martin TR, Raghu G, Maunder RJ, Springmeyer SC. The effects of chronic bronchitis and chronic air-flow obstruction on lung cell populations recovered by bronchoalveolar lavage. Am Rev Respir Dis 1985; 132:254-60.
60. Thompson AB, Daughton D, Robbins RA et al. Intraluminal airway inflammation in chronic bronchitis. Characterization and correlation with clinical parameters. Am Rev Respir Dis 1989; 140:1527-37.
61. Seltzer J, Scanlon PD, Drazen JM, Ingram RH Jr, Reid L. Morphologic correlation of physiologic changes caused by SO2-induced bronchitis in dogs. The role of inflammation. Am Rev Respir Dis 1984; 129:790-7.
62. Saetta M, Di Stefano A, Maestrelli P et al. Activated T-lymphocytes and macrophages in bronchial mucosa of subjects with chronic bronchitis. Am Rev Respir Dis 1993; 147:301-6.
63. Fournier M, Lebargy F, Le Roy Ladurie F, Lenormand E, Pariente R. Intraepithelial T-lymphocyte subsets in the airways of normal subjects and of patients with chronic bronchitis. Am Rev Respir Dis 1989; 140:737-42.
64. Di Stefano A, Turato G, Maestrelli P et al. Airflow limitation in chronic bronchitis is associated with T-lymphocyte and macrophage infiltration of the bronchial mucosa. Am J Respir Crit Care Med 1996; 153:629-32.
65. Levrier J, Duval D, Lloyd KG. Study on the effect of oral administration of carbocysteine on ventilatory parameters in the SO2 inhalation model of bronchitis in the rat. Fundam Clin Pharmacol 1992; 6:231-6.
66. Mullen JB, Wiggs BR, Wright JL, Hogg JC, Pare PD. Non-specific airway reactivity in cigarette smokers. Relationship to airway pathology and baseline lung function. Am Rev Respir Dis 1986; 133:120-5.
67. Parker CW, Bilbo RE, Reed CE. Methacholine aerosol as a test for asthma. Arch Int Med 1965; 115:452-8.
68. McFadden ER Jr. Airway responsivity and chronic obstructive lung disease. In: Cheriack NS, eds. Chronic Obstructive Pulmonary Disease. Philadelphia: W.B. Saunders 1991:21-39.
69. Moreno RH, Hogg JC, Pare PD, Mechanics of airway narrowing. Am Rev Respir Dis 1986; 133:1171-80.
70. Sweeney TD, Skornik WA, Brain JD, Hatch V, Godleski JJ. Chronic bronchitis alters the pattern of aerosol deposition in the lung. Am J Respir Crit Care Med 1995; 151:482-8.
71. Touaty E, Gerber H, Fournier M, Pariente R. SO2-induced bronchopathy decreases airway sensitization with intratracheal ovalbumin in the rat. Bull Eur Physiopathol Respir 1986; 22:329-33.
72. Long NC, Martin JG, Pantano R, Shore SA. Airway hyperresponsiveness in a rat model of chronic bronchitis: role of C fibers. Am J Respir Crit Care Med 1997; 155:1222-9.
73. Shore SA, Lilly CM, Gaston B et al. Neural networks in the lung. In: Holgate ST, eds. Immunopharmacology of the respiratory system. San Diego: Academic Press 1995:123-45.
74. Jansco G, Kiraly E, Jansco-Gaabor A. Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones. Nature 1977; 270:741-3.
75. Tomaki M, Ichinose M, Miura M et al. Elevated substance p content in induced sputum from patients with asthma and patients with chronic bronchitis. Am J Respir Crit Care Med 1995; 151:613-7.
76. Killingsworth CR, Paulauskis JD, Shore SA. Substance P content and preprotachykinin gene-I mRNA expression in a rat model of chronic bronchitis. Am J Respir Cell Mol Biol 1996; 14:334-40.