SCF(β-TrCP) ubiquitin ligase-mediated processing of NF-κB p105 requires phosphorylation of its C-terminus by IκB kinase

EMBO Journal

Volumn 19, Issue 11, 2000, Pages 2580-2591

  Orian, Amir ^a   Gonen, Hedva ^a   Bercovich, Beatrice ^a   Fajerman, Ifat ^a   Eytan, Esther ^a   Israël, Alain ^b   Mercurio, Frank ^c   Iwai, Kazuhiro ^e   Schwartz, Alan L ^d   Ciechanover, Aaron ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b INSTITUT PASTEUR   (France)

^c CELGENE CORPORATION   (United States)

^d ST LOUIS CHILDREN S HOSPITAL   (United States)

^e KYOTO UNIVERSITY   (Japan)

Author keywords

TrCP; I B kinase (I K); NF B; P105; Ubiquitin

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHOTRANSFERASE; PROTEIN P105; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING;

ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; HELA CELLS; HUMANS; I-KAPPA B KINASE; I-KAPPA B PROTEINS; MACROMOLECULAR SUBSTANCES; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; PEPTIDE SYNTHASES; PHOSPHORYLATION; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; SKP CULLIN F-BOX PROTEIN LIGASES; TRANSCRIPTION, GENETIC;

EID: 0034212379     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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