Identification of four novel interleukin-13 gene polymorphisms

Genes and Immunity

Volumn 1, Issue 5, 2000, Pages 341-345

  Pantelidis, P ^a   Jones, M G ^a   Welsh, K I ^b   Newman Taylor, A ^a   Du Bois, R M ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

Allergy; Haplotype; Interleukin 13; Polymorphisms; SSP PCR

Indexed keywords

INTERLEUKIN 13; PRIMER DNA;

ALLELE; ARTICLE; ASTHMA; CHROMOSOME 5; EXON; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETICS; HAPLOTYPE; HUMAN; IMMUNOLOGY; INTRON; NUCLEOTIDE SEQUENCE; PROMOTER REGION; UNITED KINGDOM;

ALLELES; ASTHMA; BASE SEQUENCE; CHROMOSOMES, HUMAN, PAIR 5; DNA PRIMERS; EXONS; GENE FREQUENCY; GREAT BRITAIN; HAPLOTYPES; HUMANS; INTERLEUKIN-13; INTRONS; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS);

EID: 0034208147     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6363679     Document Type: Article

References (31)

1. Robinson D, Hamid Q, Bentley A et al. Activation of CD4+ T-cells, increased T(H2)-type cytokine messenger-RNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma. J Allergy Clin Immunol 1993; 92: 313-324.
2. Robinson DS, Ying S, Bentley AM et al. Relationships among numbers of bronchoalveolar lavage cells expressing messenger-ribonucleic-acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma. J Allergy Clin Immunol 1993; 92: 397-403.
3. Robinson DS, Hamid Q, Ying S et al. Predominant TH2-like bronchoalveolar lymphocyte-t population in atopic asthma. N Engl J Med 1992; 326; 298-304.
4. Ying S, Durham SR, Corrigan CJ et al. Phenotype of cells expressing messenger-RNA for TH2-type (interleukin-4 and interleukin-5) and TH1-type (interleukin-2 and interferon-gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects. Am J Resp Cell Mol Biol 1995; 12: 477-487.
5. Punnonen J, Aversa G, Cocks BG et al. Interleukin-13 induces interleukin-4-independent IgG4 and IgE synthesis and CD23 expression by human B-cells. Proc Natl Acad Sci USA 1993; 90: 3730-3734.
6. McKenzie ANJ, Culpepper JA, Malefyt RD et al. Interleukin-13, a T-cell-derived cytokine that regulates human monocyte and B-cell function. Proc Natl Acad Sci USA 1993; 90: 3735-3739.
7. Sornasse T, Larenas PV, Davis KA et al. Differentiation and stability of T helper 1 and 2 cells derived from naive human neonatal CD4(+) T cells analyzed at the single-cell level. J Exp Med 1996; 184: 473-483.
8. Lefort S, Vita N, Reeb R et al. IL-13 and IL-4 share signal-transduction elements as well as receptor components in TF-1 cells. FEBS Lett 1995; 366: 122-126.
9. Malefyt RD, Abrams JS, Zurawski SM et al. Differential regulation of IL-13 and IL-4 production by human CD8(+) and CD4(+) T(H)0, T(H)1 and T(H)2 T-cell clones and EBV-transformed B-cells. Int Immunol 1995; 7: 1405-1416.
10. Emson CL, Bell SE, Jones A et al. Interleukin (IL)-4-independent induction of immunoglobulin (Ig)E, and perturbation of T cell development in transgenic mice expressing IL-13. J Exp Med 1998; 188: 399-404.
11. Dolecek C, Steinberger P, Susani M et al. Effects of IL-4 and IL-13 on total and allergen-specific IgE production by cultured PBMC from allergic patients determined with recombinant pollen allergens. Clin Exp Allergy 1995; 25: 879-889.
12. Punnonen J, Yssel H, deVries JE. The relative contribution of IL-4 and IL-13 to human IgE synthesis induced by activated CD4(+) or CD8(+) T cells. J Allergy Clin Immunol 1997; 100: 792-801.
13. WillsKarp M, Luyimbazi J, Xu XY et al. Interleukin-13: central mediator of allergic asthma. Science 1998; 282: 2258-2261.
14. Grunig G, Warnock M, Wakil AE et al. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 1998; 282: 2261-2263.
15. Zhu Z, Homer RJ, Wang Z et al. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999; 103: 779-788.
16. Naseer T, Minshall EM, Martin RJ et al. Expression of IL-12 and IL-13 mRNA in asthma and their modulation in response to steroid therapy. Am J Resp Crit Care Med 1997; 155: 845-851.
17. Esnault S, Benbernou N, Lavaud F et al. Differential spontaneous expression of mRNA for IL-4, IL-10, IL-13, IL-2 and interferon-gamma (IFN-gamma) in peripheral blood mononuclear cells (PBMC) from atopic patients. Clin Exp Immunol 1996; 103: 111-118.
18. Palmer LJ, Daniels SE, Rye PJ et al. Linkage of chromosome 5q and 11q gene markers to asthma-associated quantitative traits in Australian children. Am J Resp Crit Care Med 1998; 158: 1825-1830.
19. Rosenwasser LJ. The genetics of atopy. Allergy 1998; 53: 8-11.
20. Noguchi E, Shibasaki M, Arinami T et al. Evidence for linkage between asthma/atopy in childhood and chromosome 5q31-q33 in a Japanese population. Am J Resp Crit Care Med 1997; 156: 1390-1393.
21. Bleecker ER, Postma DS, Meyers DA. Genetic susceptibility to asthma in a changing environment. Ciba Found Symp 1997; 206: 90-105.
22. Symula DJ, Kelly AF, Yukihiko U et al. Functional screening of an asthma QTL in YAC transgenic mice. Nature Genet 1999; 23: 241-244.
23. van der Pow Kraan TCTM, van Veen A, Boeije LCM et al. An IL-13 promoter polymorphism associated with increased risk of allergic asthma. Genes and Immunity 1999; 1: 61-65.
24. Anderson KL, Mathieson PW, Gillespie KM. Polymorphisms not found in the IL-13 gene promoter. Science 1999; 284: 1431a.
25. McKenzie ANJ, Li X, Largaespada DA et al. Structural comparison and chromosomal localization of the human and mouse IL-13 genes. J Immunol 1993; 150: 5436.
26. Pantelidis P, Lympany PA, Foley PJ et al. Polymorphic analysis of the high affinity tumor necrosis factor receptor 2. Tissue Antigens 1999; 54: 585-591.
27. Bunce M, O'Neill CM, Barnardo CNM et al. Phototyping: comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 &DQB1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP). Tissue Antigens 1995; 46: 355-367.
28. SWISS-MODEL an automated protein modeling server running at the GlaxoWellcome Site (URL): http://www.expasy.ch/ swissmod/SWISS-MODEL.html
29. Peitsch MC. Protein modeling by e-mail. Bio-Technology 1995; 13: 658-660.
30. Peitsch MC. ProMod and Swiss-Model. Internet-based tools for automated comparative protein modelling. Biochem Soc Trans 1996; 24: 274-279.
31. Guex N, Peitsch MC. SWISS-MODEL and the Swiss-PdbViewer. An environment for comparative protein modelling. Electrophoresis 1997; 18: 2714-2723.