The relative contribution of IL-4 and IL-13 to human IgE synthesis induced by activated CD4+ or CD8+ T cells

Journal of Allergy and Clinical Immunology

Volumn 100, Issue 6 I, 1997, Pages 792-801

  Punnonen, Juha ^a   Yssel, Hans ^a   De Vries, Jan E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Allergy; B lymphocytes; Cytokines; Isotype switching; T helper cells

Indexed keywords

CD4 ANTIGEN; CD40 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 4; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY;

ALLERGY; ARTICLE; ATOPIC DERMATITIS; CYTOKINE PRODUCTION; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; NORMAL HUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; T LYMPHOCYTE SUBPOPULATION;

EID: 0031398265     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(97)70276-8     Document Type: Article

References (58)

1. Armitage RJ, Fanslow WC, Strockbine L, Sato TA, Clifford KN, Macduff BM, et al. Molecular and biological characterization of a murine ligand for CD40. Nature 1992;357:80-2.
2. Hollenbaugh D, Grosmaire LS, Kullas CD, Chalupny NJ, Braesch-Andersen S, Noelle RJ, et al. The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity. EMBO J 1992;11:4313-21.
3. Fuleihan RN, Ramesh N, Loh R, Jabara H, Rosen RS, Chatila T, et al. Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM. Proc Natl Acad Sci USA 1993;90:2170-3.
4. Di Santo JP, Bonnefoy JY, Gauchat JF, Fischer A, De Saint Basile G. CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM. Nature 1993;361:541-3.
5. Allen RC, Armitage RJ, Conley ME, Rosenblatt H, Jenkins NA, Copeland NG, et al. CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome. Science 1993;259:990-3.
6. Aruffo A, Farrington M, Hollenbaugh D, Li X, Milatovich A, Nonoyama S, et al. The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome. Cell 1993;72:291-300.
7. + T cell clones provides a costimulatory signal for human B cell activation. J Exp Med 1993;177:1575-85.
8. Macchia D, Almerigogna F, Parronchi F, Ravina A, Maggi E, Romagnani S. Membrane tumour necrosis factor-alpha is involved in the polyclonal B-cell activation induced by HIV-infected human T cells. Nature 1993;363:464-6.
9. Life P, Gauchat JF, Schnuriger V, Estoppey S, Mazzei G, Durandy A, et al. T cell clones from an X-linked hyper-immunoglobulin (IgM) patient induce IgE synthesis in vitro despite expression of nonfunctional CD40 ligand. J Exp Med 1994;180:1775-84.
10. Rickert RC, Rajewsky K, Roes J. Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice. Nature 1995;376:352-5.
11. Stamenkovic I, Sgroi D, Aruffo A, Sy MS, Anderson T. The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and alpha 2-6 sialyltransferase, CD75, on B cells. Cell 1991;66:1133-44.
12. Diaz-Sanchez, D, Chegini S, Zhang K, Saxon A. CD58 (LFA-3) stimulation provides a signal for human isotype switching and IgE production distinct from CD40. J Immunol 1994;153:10-20.
13. 2. Proc Natl Acad Sci USA 1988;85:6880-4.
14. Thyphronitis G, Tsokos GC, June CH, Levine AD, Finkelman FD. IgE secretion by Epstein-Barr virus-infected purified human B lymphocytes is stimulated by interleukin 4 and suppressed by interferon gamma. Proc Natl Acad Sci USA 1989;86:5580-4.
15. Vercelli D, Jabara HH, Arai K, Geha RS. Induction of human IgE synthesis requires interleukin 4 and T/B cell interactions involving the T cell receptor/CD3 complex and MHC class II antigens. J Exp Med 1989;169:1295-307.
16. Claassen JL, Levine AD, Buckley RH. Recombinant human IL-4 induces IgE and IgG synthesis by normal and atopic donor mononuclear cells. Similar dose response, time course, requirement for T cells, and effect of pokeweed mitogen. J Immunol 1990;144:2123-30.
17. Zhang K, Clark EA, Saxon A. CD40 stimulation provides an IFN-gamma-independent and IL-4-dependent differentiation signal directly to human B cells for IgE production. J Immunol 1991;146: 1836-42.
18. Punnonen J, Aversa G, Cocks BG, McKenzie AN J, Menon S, Zurawski G, et al. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci USA 1993;90:3730-4.
19. Punnonen J, de Vries JE. IL-13 induces proliferation, Ig isotype switching, and Ig synthesis by immature human fetal B cells. J Immunol 1994;152:1094-102.
20. McKenzie AN J, Li ANX, Largaespada DA, Sato A, Kaneda A, Zurawski SM, et al. Structural comparison and chromosomal localization of the human and mouse IL-13 genes. J Immunol 1993;150: 5436-44.
21. Smirnov DV, Smirnova MG, Korobko G, Frolova EL. Tandem arrangement of human genes for interleukin-4 and interleukin-13: resemblance in their organization. Gene 1995;155:277-81.
22. Minty A, Chalon P, Derocq JM, Dumont X, Guillemot JC, Kaghad M, et al. Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses. Nature 1993;362:248-50.
23. McKenzie ANJ, Culpepper JA, de Waal Malefyt R, Briere F, Punnonen J, Aversa G, et al. Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function. Proc Natl Acad Sci USA 1993;90:3735-9.
24. Zurawski SM, Vega Jr F, Huyghe B, Zurawski G. Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction. EMBO J 1993;12: 2663-70.
25. Kruse N, Tony HP, Sebald W. Conversion of human interleukin-4 into a high affinity antagonist by a single amino acid replacement. EMBO J 1992;11:3237-44.
26. Aversa G, Punnonen J, Cocks BG, de Waal Malefyt R, Vega Jr FJ, Zurawski SM, et al. An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors. J Exp Med 1993; 178:2213-8.
27. Zurawski SM, Chomarat P, Djossou O, Bidaud C, McKenzie ANJ, Miossec P, et al. The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor. J Biol Chem 1995;270:13869-78.
28. Hilton DJ, Zhang JG, Metcalf D, Alexander WS, Nicola NA, Willson TA. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc Natl Acad Sci USA 1996;93:497-501.
29. Caput D, Laurent P, Kaghad M, Lelias JM, Lefort S, Vita N, et al. Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha-chain. J Biol Chem 1996;271:16921-6.
30. + T cells, analyzed at the single-cell level. J Exp Med 1996;184:473-83.
31. Punnonen J, Cocks BG, de Vries JE. IL-4 induces germline IgE heavy chain gene transcription in human fetal pre-B cells: evidence for differential expression of functional IL-4 and IL-13 receptors during B cell ontogeny. J Immunol 1995;155:4248-54.
32. Zhang X, Polla B, Hauser C, Zubler RH. T cells from atopic individuals produce IgE-inducing activity incompletely blocked by anti-interleukin-4 antibody. Eur J Immunol 1992;22:829-33.
33. + 45RO-T cells develop into effector cells that secrete IL-13, IL-5, and IFN-gamma, but no IL-4, and help efficient IgE production by B cells. J Immunol 1995;154:3078-87.
34. + T cells: modulation by interleukin-4 and interleukin-12. Eur J Immunol 1996;26:571-7.
35. Kimata H, Fujimoto M, Furusho K. Involvement of interleukin (IL)-3, but not IL-4, in spontaneous IgE and IgG4 production in nephrotic syndrome. Eur J Immunol 1995;25:1497-501.
36. Kaltoft K, Hansen BH, Pedersen CB, Pedersen S, Thestrup-Pedersen K. Common clonal chromosome aberrations in cytokinedependent continuous human T-lymphocyte cell lines. Cancer Genet Cytogenet 1995;85:68-71.
37. + T cell clones. J Immunol 1992;148:738-45.
38. Manetti R, Parronchi P, Giudizi MG, Piccinni MP, Maggi E, Trinchieri G, et al. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Thl)-specific immune responses and inhibits the development of IL-4-producing Th cells. J Exp Med 1993;177:1199-1204.
39. + T lymphocytes. J Immunol 1995;155:111-7.
40. Spits H, Keizer G, Borst J, Terhorst C, Hekman A, de Vries JE. Characterization of monoclonal antibodies against cell surface molecules associated with cytotoxic activity of natural and activated killer cells and cloned CTL lines. Hybridoma 1983;2:423.
41. Chretien I, Van Kimmenade A, Pearce M, Banchereau J, Abrams JS. Development of polyclonal and monoclonal antibodies for immunoassay and neutralization of human interleukin-4. J Immunol Methods 1989;117:6781.
42. + Th0, Th1 and Th2 T cell clones and EBV-transformed B cells. Int Immunol 1995;7:1405-16.
43. + T cell clones. J Exp Med 1991;173:747-50.
44. Lundgren M, Persson U, Larsson P, Magnusson C, Smith CI, Hammarstrom L, et al. Interleukin 4 induces synthesis of IgE and IgG4 in human B cells. Eur J Immunol 1989;19:1311-5.
45. Xu L, Rothman P. IFN-gamma represses epsilon germline transcription and subsequently down-regulates switch recombination to epsilon. Int Immunol 1994;6:515-21.
46. + T lymphocytes provide helper activity for IgE synthesis in human immunodeficiency virus-infected patients with hyper-IgE. J Exp Med 1995;181:423-8.
47. + T cells showing B cell helper function and reduced cytolytic activity in human immunodeficiency virus type 1 infection. J Exp Med 1994;180:489-95.
48. Kuhn R, Rajewsky K, Muller W. Generation and analysis of interleukin-4 deficient mice. Science 1991;254:707-10.
49. vonder Weld T, Kopf M, Kohler G, Langhorne J. The immune response to Plasmodium chabaudi malaria in interleukin-4-deficient mice. Eur J Immunol 1994;24:2285-93.
50. Noben-Trauth N, Kropf P, Muller I. Susceptibility to Leishmania major infection in interleukin-4-deficient mice. Science 1996;271: 987-90.
51. Shimoda K, Kvan Deursen J, Sangster MY, Sarawar SR, Carson RT, Tripp RA, et al. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat 6 gene. Nature 1996;380:630-3.
52. Lin JX, Migone TS, Tsang M, Friedmann M, Weatherbee JA, Zhou L, et al. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-5. Immunity 1995;2:331-9.
53. Matthew DJ, Clark PA, Herbert J, Morgan G, Armitage RJ, Kinnon C, et al. Function of the interleukin-2 (IL-2) receptor gamma-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, ILl 3, and IL-15. Blood 1995;85:38-42.
54. Gauchat JF, Lebman DA, Coffman RL, Gascan H, de Vries JE. Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production. J Exp Med 1990;172:463-73.
55. Kimata H, Fujimoto M. Growth hormone and insulin-like growth factor I induce immunoglobulin (Ig)E and IgG4 production by human B cells. J Exp Med 1994;180:727-32.
56. Huang SK, Xiao HQ, Kleine-Tebbe J, Paciotti G, Marsh DG, Lichtenstein LM, et al. IL-13 expression at the sites of allergen challenge in patients with asthma. J Immunol 1995;155:2688-94.
57. + T cell clones can provide B cell help. J Immunol 1995;154:3118-27.
58. + T cell. Immunol Today 1994;15:107-10.