The genetics of atopy

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 53, Issue SUPPL. 46, 1998, Pages 8-11

  Rosenwasser, L J ^a  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; TRANSCRIPTION FACTOR;

ASTHMA; ATOPY; CONFERENCE PAPER; FOOD ALLERGY; GENE CONTROL; GENETIC PREDISPOSITION; HELPER CELL; HUMAN; PRIORITY JOURNAL;

ANIMALS; ASTHMA; HUMANS; HYPERSENSITIVITY; INTERLEUKIN-4;

EID: 0031757365     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.1998.tb04950.x     Document Type: Article

References (20)

1. Collins FS. Positional cloning: let's not call it reverse anymore. Nat Genet 1992;1:3-6.
2. Lander ES, Schork NJ. Genetic dissection of complex traits. Science 1994;265:2037-48.
3. Young RP, Dekker JW, Wordsworth PB, et al. HLA-DR and HLA-DP genotypes and immunoglobulin E responses to common major allergens. Clin Exp Allergy 1994 24 431-9
4. Moffatt MF, Hill MR, Cornelis F, et al. Genetic linkage of T-cell receptor a h complex to specific IgE responses. Lancet 1994;343:1597-1600.
5. . Cookson WO, Sharp PA, Faux JA, et al. Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome llq. Lancet 1989;1:1292-5.
6. Shirakawa T, Li A, Dubowitz M, et al. Association between atopy and variants of the b subunit of the high-affinity immunoglobulin E receptor. Nat Genet 1994;7:125-30.
7. Marsh DG, Neely JD, Breazeale DR, et al. Linkage analysis of IL-4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 1994;264: 1152-6.
8. Meyers DA, Postma DS, Panhuysen CIM, et al. Evidence for a locus regulating total serum IgE levels mapping to chromosome 5. Genomics 1994;23:464-70.
9. Postma DS, Bleecker ER, Amelung PJ, et al. Genetic susceptibility to asthma - bronchial hyperresponsiveness coinherited with a major gene for atopy. N Engl J Med 1995;333;894-900.
10. Hall IP, Wheatley A, Wilding P, et al. Association of GIu 27 P,-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects. Lancet 1995;345:1213-14.
11. n r k i J, Pak J, Martin RJ, et al. Genetic polymorphisms of the P,-adrenergic receptor in nocturnal and non-nocturnal asthma. J Clin Invest 1995;95:1635-41.
12. Daniels SE, Bhattacharrya S, James A, et al. A genomewide search for quantitative trait loci underlying asthma. Nature 1996;383:247-50.
13. Collaborative Study on the Genetics of Asthma (CSGA). A genome-wide search for asthma susceptibility loci in ethnically diverse populations. Nat Genet 1997;15:389-92.
14. Paul WE, Seder RA. Lymphocyte responses and cytokines. Cell 199+76:241-51.
15. Borish L, Mascali JJ, Klinnert M, et al. SSC polymorphisms in interleukin genes. Hum Mol Genet 1994;3:1710.
16. Rosenwasser LJ, Klemm DJ, Dresback JK, et al. Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin Exp Allergy 1995;25 Suppl 2:74-8.
17. Hershey GKK, Friedrich MF, Esswein LA, et al. The association of atopy with a gain-of-function mutation in the a subunit of the interleukin-4 receptor. N Engl J Med 1997;337:1720-5.
18. Pritchard MA, Baker E, Whitmore SA, et al. The interleukin- 4 receptor gene (IL4R) maps to 16~11.2-16~12i.n1 humans and to the distal region of mouse chromosome 7. Genomics 1991;10801-6.
19. Deichmann KA, Heinzmann A, Forster J, et al. Linkage and allelic association of atopy and markers flanking the IL4-receptor gene. Clin Exp Allergy 1998 (in press).
20. Doull IJM, Lawrence S, Watson M, et al. Allelic association of gene markers on chromosomes 5q and llq with atopy and bronchial hyperresponsiveness. Am J Respir Crit Care Med 1996;153:1280-4.