Bcl-X(L) induction during terminal differentiation of Friend erythroleukaemia cells correlates with delay of apoptosis and loss of proliferative capacity but not with haemoglobinization

Cell Death and Differentiation

Volumn 6, Issue 2, 1999, Pages 166-174

  Hafid Medheb, Khalid ^a   Poindessous Jazat, Virginie ^a   Augery Bourget, Yvette ^a   Hanania, Nicole ^a   Robert Lézénès, Jacqueline ^a  

^a HÔPITAL PAUL BROUSSE   (France)

Author keywords

Apoptosis; Bcl X(L); Erythroid differentiation; Friend erythroleukaemia; Haemoglobin synthesis

Indexed keywords

DEXAMETHASONE; DIMETHYL SULFOXIDE; HEMOGLOBIN; HEXAMETHYLENEBISACETAMIDE; IMIDAZOLE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X; SUCCINYLACETONE; ACETAMIDE DERIVATIVE; BCL2L1 PROTEIN, MOUSE; HEPTANOIC ACID DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DENSITY; CELL DIFFERENTIATION; CELL DIVISION; CELL PROLIFERATION; ERYTHROID CELL; ERYTHROLEUKEMIA CELL; HEMOGLOBIN SYNTHESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL CYCLE; CELL SURVIVAL; DRUG EFFECT; ERYTHROLEUKEMIA; METABOLISM;

ANIMALIA; MURINAE;

ACETAMIDES; ANIMALS; APOPTOSIS; BCL-X PROTEIN; CELL CYCLE; CELL DIFFERENTIATION; CELL DIVISION; CELL SURVIVAL; DEXAMETHASONE; DIMETHYL SULFOXIDE; HEMOGLOBINS; HEPTANOATES; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MICE; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR CELLS, CULTURED;

EID: 0032588672     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400466     Document Type: Article

References (33)

1. Friend C, Scher W, Holland JG and Sato T (1971) Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulaticn of erythroid differentiation by dimethyl sulfoxide. Proc. Natl. Acad. Sci. USA 68: 378-382
2. Sassa S (1976) Sequential induction of heme pathway enzymes during erythroid differentiation of mouse Friend leukemia virus-infected cells. J. Exp. Med. 143: 305-315
3. Tsiftsoglou AS and Wong W (1985) Molecular and cellular mechanisms of leukemic hemopoietic cell differentiation: an analysis of the Friend system. Anticancer Res. 5: 81-100
4. Ramsay RG, Ikeda K, Rifkind RA and Marks PA (1986) Changes in gene expression associated with induced differentiation of erythroleukemia: protooncogenes, globin genes, and cell division. Proc. Natl. Acad. Sci. USA 83: 6849-6853
5. Marks PA, Sheffery M and Rifkind RA (1987) Induction of transformed cells to terminal differentiation and the modulation of gene expression. Cancer Res. 47: 657-666
6. Gusella JF, Tsiftsoglou ASS, Volloch V, Weil SC, Neumann J and Housman DE (1982) Dissociation of hemoglobin accumulation and commitment during murine erythroleukemia cell differentiation by treatment with imidazole. J. Cell. Physiol. 113: 179-185
7. Ebert PS, Hess RA, Fryklhom BC and Tschudy DP (1979) Succinylacetone, a potent inhibitor of heme biosynthesis : effect on cell growth, heme content and δ-aminolevulinic acid dehydratase activity of malignant murine erythroleukemia cells. Biochem. Biophys. Res. Commun. 88: 1382-1390
8. Grandchamp B, Beaumont C, de Verneuil H and Nordmann Y (1985) Accumulation of porphobilinogen deaminase, uroporphyrinogen decarboxylase, and α-and β-globin mRNAs during differentiation of mouse erythroleukemic cells. Effects of succinylacetone. J Biol. Chem. 260: 9630-9635
9. L. Cell Growth Differ. 8: 1083-1089
10. L is downregulated during differentiation of human hematopoietic progenitor cells along the granulocyte but not the monocyte/macrophage lineage. Blood 89: 3199-3204
11. Yang E and Korsmeyer J (1996) Molecular thanatopsis : a discourse on the BCL2 family and cell death. Blood 88: 386-401
12. Motoyama N, Wang F, Roth KA, Sawa H, Nakayama K, Negishi I, Senju S, Zhang Q, Fujii S and Loh DY (1995) Massive cell death of immature hematopoietic cells and neurons in Bcl-X-deficient mice. Science 267: 1506-1510
13. L and apopain in the control of erythropoiesis by erythropoietin. Blood 90: 630-640
14. Koury MJ and Bondurant MC (1990) Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells. Science 248: 378-381
15. Yu H, Bauer G, Lipke K, Phillips RL and VanZant G (1993) Apoptosis and hematopoiesis in murine fetal liver. Blood 81: 373-384
16. Ruscetti SK, Janesch NJ, Chakraborti A, Sawyer ST and Hankins WD (1990) Friend spleen focus-forming virus induces factor independence in an erythropoietin-dependent erythroleukemia cell line. J. Virol. 64: 1057-1062
17. Francastel C, Poindessous-Jazat V, Augery-Bourget Y and Robert-Lézénès J (1997) NF-E2p18/mafK is required in DMSO-induced differentiation of Friend erythroleukemia cells by enhancing NF-E2 activity. Leukemia 11: 273-280
18. Tsiftsoglou AS, Gusella JF, Volloch V and Housman DE (1979) Inhibition by dexamethasone of commitment to erythroid differentiation in murine erythroleukemia cells. Cancer Res. 39: 3849-3855
19. Boise LH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nunez G and Thompson CB (1993) Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74: 597-608
20. L and Bcl-2. Blood 88: 1576-1582
21. Fairbairn LJ, Cowling GJ, Reipert BM and Dexter TM (1993) Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors. Cell 74: 823-832
22. Rodel JE and Link DC (1996) Suppression of during cytokine derivation of 32D cells is not sufficient to induce complete granulocytic differentiation. Blood 87: 858-864
23. Lagasse E and Weissman IL (1997) Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice. Cell 89: 1021-1031
24. Gusella J, Geller R, Clarke B, Weeks V and Housman D (1976) Commitment to erythroid differentiation by Friend erythroleukemia cells : a stochastic analysis. Cell 9: 221-229
25. L. Blood 87: 3837-3843
26. Terui Y, Furukawa Y, Kikuchi J, Iwase S, Hatake K and Miura Y (1998) Bcl-X is a regulatory factor of apoptosis and differentiation in megakaryocytic lineage cells. Exp. Hematol. 26: 236-244
27. Toffoli G, Viel A, Bevilacqua C, Maestro R, Tumiotto L and Boiocchi M (1989) In K562 leukemia cells treated with doxorubicin and hemin, a decrease in c-myc mRNA expression correlates with loss of self-renewal capability but not with erythroid differentiation. Leuk. Res. 13: 279-287
28. Vairo G, Innes KM and Adams JM (1996) Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival. Oncogene 13: 1511-1519
29. Huang DCS, O'Reilly LA, Strasser A and Cory S (1997) The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry. Embo J. 16: 4628-4638
30. Robert-Lézénès J, Meneceur P, Ray D and Moreau-Gachelin F (1988) Protooncogene expression in normal, preleukemic, and leukemic murine erythroid cells and its relationship to differentiation and proliferation. Cancer Res 48: 3972-3976
31. Francastel C, Mazouzi Z and Robert-Lézénès J (1992) Co-induction of c-fos and junB during the latent period preceding commitment of Friend erythroleukemia cells to differentiation. Leukemia 6: 935-939
32. Francastel C, Groisman R, Pfarr CM and Robert-Lézénès J (1994) Antisense c-jun overcomes a differentiation block in a murine erythroleukemia cell line. Oncogene 9: 1957-1964
33. Gunji H, Kharbanda S and Kufe D (1991) Induction of internucleosomal DNA fragmentation in human myeloid leukemia cells by 1-β-D-arabinofuranosylcytosine. Cancer Res. 51: 741-743