Inactivation of p33INGl Tumor suppressor affects the function of the cell cycle "checkpoints" and stability of the genome

Genetika

Volumn 36, Issue 3, 2000, Pages 385-392

  Turovets, N A ^a   Agapova, L S ^b   Kopnin, P B ^a   Tulina, N M ^b   Chumakov, P M ^b   Kopnin, B P ^a  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^b ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CELL CYCLE PROTEIN; DEMECOLCINE; DNA BINDING PROTEIN; DRUG DERIVATIVE; ING1 PROTEIN, HUMAN; MESYLIC ACID ETHYL ESTER; NUCLEAR PROTEIN; PHOSPHONOACETIC ACID; PROTEIN; SIGNAL PEPTIDE; SPARFOSIC ACID; TUMOR SUPPRESSOR PROTEIN;

ANIMAL; ARTICLE; CELL CYCLE; DNA REPLICATION; DRUG EFFECT; GENETIC TRANSDUCTION; GENETICS; GENOME; HUMAN; POLYPLOIDY; RAT; SISTER CHROMATID EXCHANGE; TUMOR SUPPRESSOR GENE;

ANIMALS; ASPARTIC ACID; CELL CYCLE; CELL CYCLE PROTEINS; DEMECOLCINE; DNA REPLICATION; DNA-BINDING PROTEINS; ETHYL METHANESULFONATE; GENES, TUMOR SUPPRESSOR; GENOME; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NUCLEAR PROTEINS; PHOSPHONOACETIC ACID; POLYPLOIDY; PROTEINS; RATS; SISTER CHROMATID EXCHANGE; TRANSDUCTION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 0034149901     PISSN: 00166758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Garkavtsev J.. Ka:an>v A.. Gudkov A., Riahowol K. Supression of the novel growth inhibitor p33INGI promotes neoplastic transformation // Nature Genet. 1996. V. 14. p. 415-420.
2. ING1 cooperates with p53 in cell growth control // Nature. 1998. V. 391. P. 295-298.
3. Levine A.J. p53. the cellular gatekeeper for growth and division // Cell. 1997. V. 88. P. 323-331.
4. Jacks T.. Weinberg R.A. Cell-cycle control and its watchman // Nature. 1996. V. 381. P. 643-644.
5. Ko L.J.. Prives C. p53: puzzle and paradism // Genes Dev. 1996. V. 10. P. 1054-1072.
6. Chernova O.B., Chernov M.V.. Agarwal M.L. et al. The role of p53 in regulating genomic stability when DNA and RNA synthesis are inhibited // Trends. Biochem. Sci. 1995. V. 20. P. 431-434.
7. Giaccia A.J.. Kastan M.B. The complexity of p53 modulation: emerging patterns from divergent signals//Genes ans Development. 1998. V. 12. P. 2973-2983.
8. Annmdson S.A..Myers T.G., Fornace A.,J.,//'. Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress // Oncogene. 1998. V. 17. P. 3287-3299.
9. Taylor W., Agarwal M., Agarwa-l A. et ill. p53 inhibits entery into mitosis whin DNA synthesis is blocked // Oncogene. 1998. V. 18. P. 283-295.
10. Agarwal M.. Agarwal A.. Taylor W. et al. A p53-dependent S-phase checkpoint helps to protect cell from DNA damage in response to starvation for pyrimidine nucleotides // Proc. Natl Acad. Sei. USA. 1998. V. 95. p. 14775-14780.
11. Livingstone L.R., White A., Sprouse.J. et al. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53 //Cell. 1992. V. 70. P. 923-935.
12. Yin Y.. Tainsky MA., Bishoff FZ. et al. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells mutant p53 alleles // Cell. 1992. V. 70. P. 937-948.
13. Harvey M., Sands A.T., Weiss R.S. et al. In vitro growth characteristics of embryo fibroblasts isolated from p53deficient mice // Oncogene. 1993. V. 8. P. 2456-2467.
14. Lee J.M.,Abralwmson L.A., Kandel R. eîal. Susceptibility to radiation carcinogenesis and accumulation of chromosome breakage in p53-deficient mice // Oncogene. 1994. V. 9. P. 3731-3736.
15. Agapova L.S., llyinskaya G.V., Turovets N.A. et al. Chromosome changes caused by alterations of p53 expression//Mut. Res. 1996. V. 354. P. 129-138.
16. Fukaxawa K., Wiener F.. Woud G.F.V., Mai S. Genomic instability and apoptosis are frequent in p53 deficient young mice//Oncogene. 1997. V. 15. P. 1295-1302.
17. Ishi:aka Y., Chernov M.V., Burns CM.. Stark G.R. p53dependent growth arrest of REF52 cells containing newly amplified DNA // Proc. Natl Acad. Sei. USA. 1995. V. 92. P. 3224-3228.
18. Agapova L.S., Ivanov AV., Sablina A.A. et al. p53-dependent effects of RAS oncogene on chromosome stability and cell cycle checkpoints // Oncogene. 1999. V. 18. P. 3135-3142.
19. Ossovskaya V.S., Ma:o I.A., Chernov M.V. et al. Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains // Proc. Natl Acad. Sei. USA. 1996. V. 93. P. 10309-10314.
20. Sablina A., Agapova L.S., Chumakov P.M., Kopnin B.P. p53 does not control spindle assembly cell cycle checkpoint but mediates G] arrest in response to disruption of microtubule system // Cell Biol. Int. 1999. V. 23.
21. Stark G.R. Regulation and mechanisms of mammalian gene amplification // Adv. Cancer Res. 1993. V. 61. P. 87-113.
22. Kelman Z. PCNA: structure, functions and interactions // Oncogene. 1997. V. 14. P. 629-640.
23. Dutta A.,RuppertJ.M.,AsterJ.C., Winchester E. Inhibition of DNA replication factor RPA by p53 // Nature. 1993. V. 365. P. 79-82.
24. Merritt A., Allen T., Pötten C., Hickman J. Apoptosis in small intestinal epithelia from p53-null mice: evidence for a delayed, p53-idependent G2/M-assodated cell death after y-irradiation // Oncogene. 1997. V. 14. P. 2759-2766.
25. Di Leonardo A., Linke S.P.,Clarkin K., Wahl G.M. DNA damage triggers a prolonged p53-dependent G, arrest and long term induction of Cipl in normal human fibroblasts//Genes Dev. 1994. V. 8. P. 2540-2551.
26. Khan S.H., Wahl G.M. p53 and pRb prevent rereplication in response to microtubule inhibitors by mediating a reversible G, arrest//Cancer Res. 1998. V. 58. P. 396-401.
27. Lanni J.S., Jacks T. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption // Mol. Cell. Biol. 1998. V. 18. P. 1055-1064.
28. Notterman D., Young S., Wainger B., Levine A.J. Prevention of mammalian DNA reduplication, following the release from the mitotic spindle checkpoint, requires p53 protein, but not p53-mediated transcriptional activity//Oncogene. 1998. V. 17. P. 2743-2751.
29. Perry M.E.. Commane M., Stark G.R. Simian virus 40 large tumor antigène alone or two cooperating oncogenes convert REF52 cells to a state permissive for gene amplification // Proc. Natl Acad. Sei. USA. 1992. V. 89. P. 8112-8116.
30. Chcrnova O., Chernov M., Ishizaka Y. et al. MYC abroates p53-mediated cell cycle arrest in N-(phosphoacetyl)-L-aspartate-treated cells, permitting CAD gene amplification//Mol. Cell. Biol. 1998. V. 18. P. 536-545.
31. Ouchi T., Monteiro A.N.A., August A. et al. BRCAI regulates p53-dependent gene expression // Proc. Natl Acad. Sei. USA. 1998. V. 95. P. 2302-2306.
32. Zhang H., Somasundaram K., Peng Y. et al. BRCAI physically associates with p53 and stimulates its transcriptional activity//Oncogene. 1998. V. 16. P. 1713-1721.
33. Englert C., Maheswaran S., Garvin A.J. et al. Induction of p21 by the Wilms' tumor suppressor gene WT1 // Cancer Res. 1997. V. 57. P. 1429-1434.